Exam Details
Subject | ||
Paper | paper 1 | |
Exam / Course | combined medical services examination | |
Department | ||
Organization | union public service commission | |
Position | ||
Exam Date | 2015 | |
City, State | central government, |
Question Paper
1. The following statements in relation to right ventricular myocardial infarction are correct except:
It may occur along with inferior wall myocardial infarction
The ECG shows segment elevation in right precordial leads
Prognosis in right ventricular infarction is worse than the left ventricular myocardial infarction
The treatment includes intravenous diltiazem
2. Atrial myxoma is associated with the following except:
Fever
Weight loss
Systolic murmur at apex
Subungual splinter haemorrhage
3. Match List I with List II and select the correct answer using the code given below the lists:
List I (Auscultatory findings) List II (Cardiac condition)
A. Wide fixed split in the second heart sound 1. Pulmonary hypertension hypertension
B. Continuous machinery murmur 2. Atrial septal defect
C. Muffled heart sounds 3. Patent ductus arteriousus
D. Wide variable split in the second heart sound 4. Pericardial effusion
Code: A B C D
2 4 3 1
2 3 4 1
1 4 3 2
1 3 4 2
4. Match List I with List II and select the correct answer using the code given below the lists:
List I (Emergency drugs) List II (Clinical condition)
A. Amiodarone 1. A-V Block, mobitz type II
B. Adenosine 2. Atrial fibrillation
C. Digoxin 3. Ventricular tachycardia
D. Atropine 4. Paroxysmal supraventricular tachycardia Code: A B C D
1 2 4 3
1 4 2 3
3 2 4 1
3 4 2 1
5. Klebsiella pneumonia has the following characteristics except:
Upper lobes are frequently involved
Pneumatocoele may occur commonly
Empyema is much more common
Lung abscess formation is very uncommon
6. Match List I with List II and select the correct answer using the code given below the lists:
List-I (Disease) List-II (Antigen leading to hypersensitivity pneumonitis)
A. Bagassosis 1. Oak, Cedar, Pine dust
B. Byssinosis 2. Moldy hay
C. Farmer's lung 3. Cotton
D. Wood worker's lung 4. Sugarcane dust
Code: A B C D
4 3 2 1
4 2 3 1
1 3 2 4
1 2 3 4
7. Which one of the following is not likely to be associated with pulmonary fibrosis?
Coal miners' lung
Primary biliary cirrhosis
Asbestosis
Ankylosing spondylitis
8. Which of the following is/are a feature/features of severity in immediate assessment of acute severe asthma?
1. Pulse rate >110 per min
2. Pulsus paradoxus
3. Unable to speak in sentences Select the correct answer using the code given below:
1 only
2 and 3 only
1 and 3 only
2 and 3
9. Cavitating pulmonary lesions can be seen in the following except:
Sarcoidosis
Tuberculosis
Carcinoma of lung
Histoplasmosis
10. A 35 year old 40 kg male patient was diagnosed to be a case of pulmonary tuberculosis. The appropriate conventional regimen of antitubercular drugs would be:
Rifampicin 450 mg Isoniazid 300 mg Pyrazinamide 1500 mg
Rifampicin 600 mg Isoniazid 300 mg Pyrazinamide 1000 mg
Rifampicin 450 mg Isoniazid 200 mg Pyrazinamide 1000 mg
Rifampicin 450 mg Isoniazid 200 mg Pyrazinamide 1500 mg
11. Which of the auscultatory signs is absent in mitral stenosis in the presence of atrial fibrillation?
Mid diastolic murmur
Pre -systolic accentuation
Variable first heart sound
P2 accentuation
12. Which one of the following is not recommended in immediate treatment of acute severe asthma?
Oxygen supplementation
High doses of inhaled B2 -adrenoreceptor agonists
Systemic corticosteroids
Intravenous aminophylline
13. Which one of the following is not a feature of type 2 respiratory failure
pCO2 38 mmHg, and pO2 50 mmHg
pCO2 68 mmHg, and pO2 50 mmHg
Papilloedema
Asterixis
14. Which of the following drugs is not given in dilated cardiomyopathy?
Beta blocker
Calcium channel blocker
Spiranolactone
ACE inhibitors
15. Which of the following features are related to Zollinger Ellison syndrome?
1. Aggressive and refractory peptic ulceration
2. Unregulated gastrin release
3. Beta islet cell tumour of pancreas
4. Diarrhoea present in upto 50% cases Select the correct answer using the code given below:
1 and 2 only
3 and 4
2 and 3
2 and 4
16. In which of the following diseases, primary skin lesions are not seen?
Leptospirosis
SLE
Hepatitis-B
Infectious mononucleosis
17. Which of the following is not a common feature of hypersensitivity pneumonitis?
Raised C-Reaction Protein
Chest X-ray may be normal
Lung biopsy may be diagnostic
Eosinophilia
18. Consider the following statements with regard to duodenal ulcers:
1. They occur most often in the second part of duodenum.
2. Infection with H. pylori and NSAID-induced injury account for the majority of duodenal ulcers.
3. Malignant duodenal ulcers are extremely rare.
4. Eradication of H. pylori has greatly reduced the recurrence rates in duodenal ulcers. Which of the above statements is/are correct?
1 and 3 only
3 and 4 only
2 and 4 only
and 4
19. Carcinoid tumours commonly arise from:
G.cells in pancreas
Argentaffin cells of small intestine
Pancreatic endocrine tumour
Colon polyps
20. Which of the following viral markers signifies the ongoing viral replication in the case of Hepatitis-B infection?
Anti-HBs
Anti-HBc
HBe Ag
HBs Ag
21. The following may result in polyuria except:
Chronic renal failure
Hypoadrenalism
Hypercalcaemia
Lithium carbonate therapy
22. Regarding adult polycystic kidney disease, which one of the following statements is not correct?
Inherited as autosomal dominant with 100% penetrance
Often associated with hepatic cysts
Associated with increased incidence of subarachnoid haemorrhage
Renal cell carcinoma is a frequent association
23. Which of the following is not a feature of chronic renal failure?
Hyperparathyroidism
Osteomalacia
Hyperthyroidism
Decreased 25(OH)2 vitamin D3 level
24. A patient with past history of recurrent headache, presents with irregular, dazzling, enlarging visual phenomena that obstructs vision in the affected region and remains for several minutes. The symptoms are indicative of:
Acute angle closure glaucoma
Retinal detachment
Migraine
Intumescent cataract
25. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (Disease) List-II (Cause)
A. Macrocytic anaemia 1. Iron deficiency
B. Microcytic anaemia 2. Hypothyroidism
C Hemolytic anaemia 3. Vitamin B12 deficiency
D. Megaloblastic anaemia 4. Alpha methyldopa
Code: A B C D
3 1 4 2
3 2 1 4
2 1 4 3
1 4 3 2
26. Haemolysis in G6PD (glucose 6 phosphate dehydrogenase) enzyme deficiency may occur with all of the following drugs except:
Primaquine
Phenacetin
Probenecid
Penicillin
27. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (Blood picture) List-II (Type of Anaemia)
A. Microcytic, hypochromic red cells 1. Vitamin B12 deficiency anaemia
B. Macrocytic, hypochromic red cells 2. Thalassemia major
C Large number of early, intermediate and late erythroblasts 3. Aplastic anaemia
D. Low reticulocyte count 4. Iron-deficiency anaemia
Code: A B C D
1 4 2 3
2 3 4 1
4 1 2 3
3 1 2 4
28. Which of the following conditions does not cause pancytopenia?
Hypersplenism
Aplastic anaemia
Cancer infiltrating the bone-marrow
Haemolysis from G6PD enzyme deficiency
29. Which of the following drugs does not cause oedema?
Growth hormone
Beta blocker
Anabolic steroids
Calcium-channel blockers
30. A patient of hypoglycemia fails to regain consciousness after blood glucose is restored to normal. The complication that carries high mortality and morbidity is:
Cerebral oedema
Lacunar infarct
Post ictal state
Cerebral haemorrhage
31. An adult patient presents with systemic hypertension, renal calculus disease and peptic ulcer disease. Which one of the following is most likely occurrence in this case?
Milk alkali syndrome
Hypervitaminosis D
Primary hyperparathyroidism
Tubulo interstitial renal disease
32. Match List-I with List-II and select the correct answer using the code given below the lists
List-I (types of hyperlipidemia) List-II (feature)
A. Hyperchylomicronaemia 1. Palmar plantar xanthoma
B. Hyperbetalipoproteinaemia 2. Subcutaneous extensive tendon xanthoma
C Type III hyperlipoproteinaemia 3. Eruptive xanthoma over buttocks
D. Familial LPL deficiency 4. Triglyceride level above 1000 mg
Code: A B C D
3 1 2 4
3 2 1 4
4 1 2 3
4 2 1 3
33. Which of the following is least suggestive of poliovirus infection?
Low grade fever and malaise with complete resolution in 2 to 3 days
Biphasic illness with several days of fever, then meningeal symptoms and asymmetric flaccid paralysis 5 to 10 days later
Descending motor paralysis with preservation of tendon reflexes and absent sensation
Failure to isolate a virus from the CSF in the presence of marked meningismus
34. The following conditions can cause interstitial nephritis except:
Infections
Hepatorenal syndrome
Lymphoma
Sarcoidosis
35. Which of the following are characteristics features of tuberculoid leprosy?
1. Type 2 lepra reaction
2. A few lesions with well demarcated edges
3. Early and marked nerve damage
4. Tendency to heal spontaneously Select the correct answer using the code given below:
2 and 3
3 and 4
1 and 4
2 and 3 only
36. Which of the following immunological reactions occurs in Goodpasture syndrome
Type I atopy
Type II cytotoxic
Type III immune complex
Type IV cell mediation
37. Regarding erythema nodosum leprosum, which one of the following is not correct?
It is usually during initiation of treatment
Tender subcutaneous nodules observed
Lymphadenopathy is common
Ophthalmic involvement can occur
38. The most common microorganism known to cause tropical pyomyositis is
Streptococcus viridans
Staphylococcus albus
Klebseilla pneumonia
staphylococcus aureus
39. Following are the common features of Cushing's syndrome except:
Truncal obesity
Osteoporosis
Distal myopathy
Glucose intolerance
40. A farmer presents with history of fever and chills, severe bodyache, headache, conjuctival suffusion and jaundice. He has severe muscle tenderness, leukocytosis and mild uraemia. The most likely diagnosis would be:
Leptospirosis
Typhoid fever
Typhus
Viral hepatitis
41. Consider the following statements regarding falciparum malaria: 1. The mortality rises steeply when the proportion of infected erythrocytes increases above 3 percent. 2. The patient may develop hypoglycemia even when not treated with quinine. Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
42. "Loeffler's syndrome" is characterized by:
Transient, migratory pulmonary infiltrations
Fibrosis in the pulmonary apices
Fibrosis in the base of one or both lungs
Miliary mottling
43. Keyboard operators and typists are especially susceptible to injury of the
Axillary nerve
Median nerve
Ulnar nerve
Radial nerve
44. Which of the following is not a clinical feature of Kwashiorkor?
Bipedal oedema
Visible severe wasting
Low serum albumin
Moon face
45. Match List I with List II and select the correct answer using the code given below the lists:
List I (Clinical features) List II (Deficiency of)
A. Flaky paint rashes of lower extremity 1. Niacin
B. Goose-hump skin lesion 2. Thiamine
C. Confabulation 3. Zinc
D. Dementia 4. Vitamin A
Code: A B C D
1 2 4 3
1 4 2 3
3 4 2 1
3 2 4 1
46. Consider the following:
1. Psoriasis
2. Atopic dermatitis
3. Leprosy
4. Vitiligo PUVA therapy can be used to treat which of the above?
1 and 2 only
2 and 3
2 and 4
3 and 4
47. The cutaneous viral infection which is commonly seen in children and characterized by single or multiple pearly-white skin colored smooth dome shaped papules with central pitting is:
Chicken pox
Herpes zoster
Molluscum contagiosum
Verruca vulgaris
48. Consider the following statements about polyarticular juvenile rheumatoid arthritis:
1. It is more common in girls
2. Five or more joints are affected within the first six months of onset
3. Uveitis occurs in 95% patients
4. Rheumatoid factor may be negative
Which of the statements given above are true
1 and 4 only
2 and 4
3 and 4
2 and 3 only
49. Consider the following statements regarding schizophrenia:
1. Patient feels that other persons put thoughts into his mind
2. Patient feels that he is being punished for his wrong doings
3. He may be in a state of catatonia Which of the statements given above is/are correct?
1 only
2 and 3 only
1 and 3 only
2 and 3
50. Lithium carbonate is employed in the following conditions except:
To treat acute episodes of mania
To prevent recurrence of mania
To prevent depression in bipolar disorders
To prevent depression in unipolar disorders
51. The following conditions can cause protein-losing enteropathy except:
Ulcerative colitis
Irritable bowel syndrome
Celiac disease
Lymphoma
52. Which of the following ocular findings is a component of Foville syndrome?
Lateral gaze palsy
6th N Palsy
3rd N Palsy
Nystagmus
53. The following features are suggestive of Behcet's syndrome except:
Orogenital ulcers
Polyarthritis
Uveitis
Livedo reticularis
54. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (drug) List-II (side effect)
A. Phenytoin sodium 1. Hypothyroidism
B. Para aminosalicylic acid 2. Hepatotoxicity
C Rifampicin 3. 8th nerve damage D. Streptomycin
4. Cerebellar dysfunction
Code: A B C D
4 1 2 3
4 2 1 3
3 2 1 4
2 1 4 3
55. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (disease state) List-II (clinical feature)
A. Pemphigus vulgaris 1. Acro -osteolysis
B. Psoriasis 2. Brachydactyly
C. Turner syndrome 3. Koebner phenomenon
D. Primary hyperparathyroidism 4. Nikolsky sign
Code: A B C D
1 2 3 4
1 3 2 4
4 2 3 1
4 3 2 1
56. A 10 year old child "blanks out" in class (e.g. stops talking midsentence and then continues as if nothing had happened). During spells there is slight quivering of lips. What is the most probable diagnosis?
Mutism
Autism
Adjustment disorder
Absence seizure
57. A 45 year old man presents with hematuria. Renal biopsy demonstrates a focal necrotizing glomerulitis with crescent formation. The patient gives history of intermittent hemoptysis and intermittent chest pain of moderate intensity. A previous chest X-ray had demonstrated multiple opacities, some of which were cavitated. The patient also has chronic cold like nasal symptoms. What is the most probable diagnosis?
Aspergillosis
Polyarteritis nodosa
Renal carcinoma metastatic to lung
Wegner's granulomatosis
58. A 28 year old woman presented with high grade fever, cough, diarrhea and mental confusion for 4 days. X-ray chest revealed bilateral pneumonitis. Search for etiology will most likely reveal
Streptococcus pneumoniae
Staphylococcus aureus
Legionella pneumophila
Pseudomonas aeruginosa
59. Congenital heart disease associated with pre-excitation is:
Atrial septal defect
Bicuspid aorta valve
Ebstein's anomaly
Patent ductus arteriosus
60. Hockey-stick appearance in echocardiography is a feature of:
Mitral stenosis
Mitral incompetence
Aortic stenosis
Aortic regurgitation
61. Hutchinson sign is a feature of ocular involvement by which of the following viruses?
Herpes simplex
Epstein-Barr virus
Cytomegalovirus
Herpes zoster
62. Well recognised side-effects of prolonged phenytoin use may result in all except:
Hirsutism
Lymphadenopathy
Ataxia
Hypoglycaemia
63. First order neurons in the visual pathway are constituted by:
Bipolar cells
Amacrine cells
Ganglion cells
Rods and cones
64. Level of which hormone is likely to increase after hypothalamic ablation?
Growth hormone
Prolactin
FSH
ACTH
65. A 50 year old patient with signs of peripheral neuropathy is found to have diabetes mellitus. He has no ocular symptoms. When would you refer this patient for retina evaluation?
When he develops ocular symptoms
Immediately
If he needs insulin for blood sugar
Five years after diagnosis
66. Which one of the following tests has the highest chance of detecting HIV infection in a blood donor during the window period?
Demonstration of antibody to HIV by ELISA
CD4 count
P24 antigen detection
Western blot test
67. The following are exotoxin-mediated infections except:
Cholera
Typhoid
Botulism
Tetanus
68. The following tests can be used for diagnosing celiac disease except:
Anti-gliadin antibodies
Anti-nuclear antibodies
Anti-endomycial antibodies
Anti-tissue transglutaminase antibodies
69. Which one of the following is not an early complication of acute myocardial infarction?
Papillary muscle dysfunction
Ventricular septal defect
Pericarditis
Dressler's syndrome
70. Consider the following conditions:
1. Thyrotoxicosis, phaeochromocytoma and acromegaly
2. Haemochromatosis
3. Conn's syndrome (primary hyperaldosteronism)
4. Pancreatic carcinoma
Which of the above may result in secondary diabetes mellitus?
2 and 3 only
2 and 4
3 and 4
2 and 3
71. Consider the following statements: Gastric lavage is contraindicated in children in case of
1. iron poisoning
2. kerosene poisoning
3. corrosive poisoning
4. aspirin poisoning Which of the above statements are correct?
3 and 4
2 and 4
2 and 3 only
1 and 3
72. Consider the following:
1. Visible gastric peristalsis
2. Bilious vomiting
3. Palpable mass
4. Melena
Which of the above is/are the feature/features of infantile hypertrophic pyloric stenosis?
2 and 3
1 and 3 only
2 and 4
4 only
73. A very large ventricular septal defect should be operated
In school going age
Only if CHF is uncontrolled
Before six months of age
Soon after birth
74. A 2 year old boy is being evaluated for severity of malnutrition. The child weighs 7 kg and measures 74 cm in length. Expected (median) weight for height, and height for age for this child are 9 kg and 86 cm respectively. According to WHO classification of undernutrition, which of the following is the correct category for this child?
Wasted, stunted
Wasted, severly stunted
Severly wasted, stunted
Severly wasted, severly stunted
75. Catch-up diet for treatment of severe malnutrition in children should achieve the following:
Calorie 150-220 kcal/kg/d; protein 4-6 g/kg/d
Calorie 125-175 kcal/kg/d; protein 4-6 g/kg/d
Calorie 125-175 kcal/kg/d; protein 2-4 g/kg/d
Calorie 150-220 kcal/kg/d; protein 2-4 g/kg/d
76. Which one of the following is not a feature of vitamin D deficiency rickets?
Decrease in parathyroid hormone level
Decrease in gut calcium absorption
Decrease in renal phosphate excretion
Increase in serum alkaline phosphatase
77. A child presents with moderate fever for two months. On examination, she had moderate anaemia and a few petechia. All the following can be the diagnosis except:
Acute leukemia
Tuberculosis
Typhoid
Juvenile rheumatoid arthritis
78. Which of the following statements is true regarding juvenile chronic myeloid leukemia?
Philadelphia chromosome is negative.
Thrombocytopaenia is uncommon.
The prognosis is better than the adult form of chronic myeloid leukemia.
Single agent chemotherapy with busulfan or hydroxyurea can achieve remission.
79. Consider the following features:
1. X-linked recessive inheritance
2. Atopic dermatitis
3. Low serum levels of IgA Which of the above is/are the characteristic features of Wiskott-Aldrich syndrome?
1 only
1 and 2 only
3 only
2 and 3
80. Lisch nodules are seen in which of the following conditions?
von Recklinghausen's disease
Louis-bar syndrome
Tuberous sclerosis
von Hippel-Lindau syndrome
81. A 5 year old child presented with microcytic hypochromic anaemia. Serum ferritin is low. Which of the following is least likely?
Celiac disease
Thalassemia major
Nutritional anaemia
Paroxysmal nocturnal haemoglobinuria
82. An infant can sit leaning forward on his hands. He bounces actively when made to stand. He laughs aloud and becomes concerned when the mother moves away. What is his most likely age?
12 weeks
16 weeks
22 weeks
28 weeks
83. Match List I with List II and select the correct answer using the code given below the lists:
List I (Association with hepatomegaly) List II (Presentation)
A. Skin lesion 1. Histiocytosis
B. Engorged neck veins 2. Galactosemia
C. Cataract 3. Toxoplasmosis
D. Hydrocephalus 4. Constrictive pericarditis
Code: A B C D
1 4 2 3
2 3 4 1
4 1 3 2
3 4 2 1
84. The most common type of juvenile rheumatoid arthritis is:
Rheumatoid factor positive polyarticular
Rheumatoid factor negative polyarticular
Pauciarticular type
Systemic onset type
85. An 8 year old boy presented to the Emergency Department on the fourth day of fever during a dengue epidemic. He had a mild erythematous rash on his body and no bleeding from any site. His BP was 110/70 mmHg and pulse was 94/minute. Hess test was positive. Dengue serology report is awaited. Platelet count is 30,000/cm3 and PCV: 36%. What is the treatment of choice?
Plenty of oral/ IV fluids and observation
Emergency platelet transfusion to raise platelets above 50,000/ cm3
IV anti-D immune globulin
Give antipyretic and wait for dengue serology report
86. Match List I with List II and select the correct answer using the Code given below the lists:
List I (Antidote) List II (Poison/Drug)
A.Calcium sodium edetate1. Cyanide
B. Sodium nitrite 2. Nitrobenzene
C. Methylene blue 3. Lead
D. Atropine 4. Organophosphate
5. Kerosene
Code: A B C D
1 2 3 4
2 3 4 1
3 1 2 5
3 1 2 4
87. Match List I with List II and select the correct answer using the code given below the lists:
List I (Diseases) List II (Laboratory parameters)
A. Thalassemia major 1. Increased serum iron, decreased TIBC, increased serum ferritin
B. Iron deficiency anaemia 2. Decreased serum iron, increased TIBC, decreased serum ferritin
C. Nephrotic syndrome 3. Decreased serum iron, decreased TIBC, increased serum ferritin
D. Acute iron poisoning 4. Increased serum iron, normal TIBC, normal serum ferritin
Code: A B C D
4 3 2 1
4 2 3 1
1 2 3 4
1 3 2 4
88. A previously well 2 year old boy presents with a brief generalized seizure. There is no past or family history of seizures. On examination, child is alert, active, febrile with axillary temperature of 39.40C. Except for bilateral tonsillar enlargement and congestion, systemic examination is normal. Management at this time may include:
1. Immediate reduction of body temperature
2. Intravenous diazepam and phenytoin, followed by a lumbar puncture
3. Institution of phenytoin for maintenance therapy for at least one year
4. Rectal diazepam every 8 hourly for 2-3 days to reduce the risk of recurrence Select the correct answer using the code given below:
1 and 2 only
1 and 4 only
3 and 4
2 and 4
89. Match List I with List II and select the correct answer using the code given below the lists:
List I (Endocrinological disorders) List II (Results of investigations)
A. Hypothyroidism 1. Increased urinary excretion of catecholamines
B. Cushing's syndrome 2. Increased urinary 17-ketosteroids
C. Pheochromocytoma 3. Hypocalcaemia and hyperphosphataemia
D. Hypoparathyroidism 4. TSH levels are increased and T3, T4 levels are decreased
Code: A B C D
4 2 1 3
4 1 2 3
3 2 1 4
3 1 2 4
90. Match List I with List II and select the correct answer using the Code given below the lists:
List I Clinical presentation) List II (Disease pathology)
A. Extrapyramidal cerebral palsy 1. Stroke
B. Spastic quadriplegia 2. Multicystic encephalomalacia
C. Spastic hemiplegia 3. Periventricular leukomalacia
D. Spastic diplegia 4. Bilirubin encephalopathy
Code: A B C D
3 1 2 4
1 2 3 4
4 3 2 1
4 2 1 3
91. Consider the following pairs: National Park State
1. Keoladeo Ghana National Park ...... Rajasthan
2. Sultanpur National Park ...... Uttar Pradesh
3. Valley of Flowers National Park ...... Himachal Pradesh
Which of the pairs given above is/are correctly matched?
1 only
2 and 3 only
1 and 3 only
2 and 3
92. The Himalayas have snowline at higher altitude compared to that in the Alps mountains. This is because
Himalayas are higher than the Alps
Himalayas face the monsoon winds
Himalayas are located in lower latitudes
Himalayas have denser forest cover
93. The knowledge of genome sequence is important to
1. understand how genes work together in the growth and development of an entire organism.
2. study the regulatory regions in the genome outside the gene that controls expression of genes.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
94. Besides the Sunderbans, mangrove forests are also to be found in
1. Bhitarkanika
2. Godavari delta
3. Pichavaram
4. Kaveri (Cauvery) delta
Select the correct answer using the code given below:
2 and 4 only
3 and 4 only
2 and 3 only
3 and 4
95. Which of the following statements is not correct?
In the preparation of vinegar in the households, dried fruits can be used.
Vinegar making involves fermentation by yeast.
Vinegar is actually acetic acid.
A fruit juice containing or more sugar cannot be made into vinegar in the households.
96. Which one of the following viruses was exploited to create genetically engineered virus "onyx-15", an oncolytic virus to target and eliminate cancer cells?
Parvovirus
Adenovirus
Pox virus
Herpes simplex virus
97. Which one of the following is not included in the Preamble of the Constitution of India?
Secular Republic
Socialist Republic
Federal Republic
Democratic Republic
98. Consider the following milk borne diseases:
1. Brucellosis
2. Listeriosis
3. Salmonellosis
Which of the above can be controlled by pasteurization?
1 only
2 and 3 only
3 only
2 and 3
99. Who of the following is the Chairman of Rajya Sabha?
The Prime Minister
The Speaker of Lok Sabha
The Vice President of India
The President of India
100. Consider the following statements:
1. Fly ash can be added to agricultural soil to enhance its water holding capacity.
2. Fly ash can be used in the manufacture of bricks and blocks for construction purposes. Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
101. "Ecological niche" refers to the
amount of autotrophs available for consumption of the grazing population.
relationship of an animal with the surrounding animals.
position of an animal with reference to its species composition.
positional and functional relationship of an organism in an ecosystem.
102. Which one the following is not required for the formation of photochemical smog?
Oxygen
Oxides of nitrogen
Carbon monoxide
Sunlight
103. The 'Nirbhaya Fund' set up by the Government of India is for:
Ensuring the safety of women
Promoting the financial literacy of rural poor
Promoting Self-Help Groups of women
Providing free education
104. What is "Solar Impulse which was recently in the news?
A Central Government sponsored scheme to promote the production of solar energy
A spacecraft sent by NASA to study a comet moving towards Sun
A project of India in collaboration with NASA to study the impact of solar flares on Earth
A round-the-world flight powered only by the solar energy
105. Consider the following statements:
1. In food preservation by irradiation, ionising rays are used.
2. Irradiation does not affect the colour, odour, taste, pH and levels of vitamin contents in the foods.
Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
106. Kutch (in Gujarat) has the existence of a large number of salt pans. What could be the most valid reason/reasons for this?
1. Existence of creeks and mudflats
2. Higher evaporation rate
3. Presence of vast intertidal zone Select the correct answer using the code given below:
1 and 2 only
2 only
1 and 3 only
2 and 3
107. Most of the ozone in the atmosphere is concentrated in the:
Ionosphere
Mesosphere
Stratosphere
Troposphere
108. Consider the following:
1. Lactic acid
2. Sorbic acid
3. Sulphurous acid
Which of the above are food preservatives?
1 and 2 only
2 and 3 only
None of these
2 and 3
109. With reference to "DNA Microarray" technology, which of the following statements is/are correct?
1. It helps in identifying the genes involved in a disease by comparing the gene expressions between the tissues from a healthy and an infected person.
2. It allows visualizing the activity of hundreds of genes simultaneously.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
110. Artemesinin is a drug derived from
Plant
Fungus
Rock
Blue-green alga
111. Which of the following can be used to extract heavy metals from water?
1. Aluminium oxide
2. Cellulose
3. Silica
Select the correct answer using the code given below:
1 only
2 and 3 only
1 and 3 only
2 and 3
112. Which one of the following represents the correct sequence of vegetational transitions with increasing latitude?
Rain forest- deciduous forest- coniferous forest
Rain forest- coniferous forest- deciduous forest
Deciduous forest- rain forest- coniferous forest
Coniferous forest- rain forest- deciduous forest
113. Consider the following statements:
1. LED lamps have shorter life span as compared to incandescent bulbs.
2. LED lamps are made by using semi-conductor material.
3. LED lamps are more expensive than conventional sources of lighting.
Which of the statements given above are correct?
1 and 2 only
2 and 3 only
1 and 3 only
2 and 3
114. In India, ecologists consider "sacred groves" very valuable because of their role in
meeting fuelwood and medicinal needs of local people.
protection of biodiversity that has vanished from surrounding areas due to exploitation by man.
stabilization of climate and reduction of global warming.
socio-cultural and religious interactions among traditional communities of different regions.
115. The "Cry1Ac", often in news is
a gene that enables some crop plants to fight pests.
another strain of virus responsible for bird-flue that occurred in China.
a gene used in making the transgenic rice known as "golden rice".
None of these
116. Excessive accumulation of nitrates in water bodies can result in:
1. Proliferation of biodiversity
2. Algal blooms
3. Acidification
Select the correct answer using the code given below:
1 only
2 and 3 only
2 only
2 and 3
117. According to the United Nations Convention on the Rights of the Child, which of the following is/are the right/rights of the children?
1. Right to expression
2. Right to recreation
3. Right to name and nationality
Select the correct answer using the code given below:
1 and 2 only
3 only
2 and 3
None of these is a Right of the children
118. In the context of genetic engineering, which of the following statements is/are correct?
1. Vector mediated recombinant gene transfer can be done from one eukaryote to another eukaryote only.
2. Vector mediated recombinant gene transfer can be done from animal cell to plant cell.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
119. What is the importance of a plant named jatropha that is frequently in the news?
It is a wild variety of rice of North-east India rich in vitamin A and iron.
it is a bio-diesel yielding plant that can grow well in areas of low rainfall.
It is a genetically modified pest-resistant potato plant.
It is a highly drought-resistant wild variety of pearl millet adopted for cultivation in dry areas of South India.
120. Gene silencing means a gene which would be expressed under normal circumstances is switched off by cell machinery. Which one of the following cellular components is not involved in gene silencing?
Micro RNA
Double stranded RNA
Ribosomal RNA
Si RNA
It may occur along with inferior wall myocardial infarction
The ECG shows segment elevation in right precordial leads
Prognosis in right ventricular infarction is worse than the left ventricular myocardial infarction
The treatment includes intravenous diltiazem
2. Atrial myxoma is associated with the following except:
Fever
Weight loss
Systolic murmur at apex
Subungual splinter haemorrhage
3. Match List I with List II and select the correct answer using the code given below the lists:
List I (Auscultatory findings) List II (Cardiac condition)
A. Wide fixed split in the second heart sound 1. Pulmonary hypertension hypertension
B. Continuous machinery murmur 2. Atrial septal defect
C. Muffled heart sounds 3. Patent ductus arteriousus
D. Wide variable split in the second heart sound 4. Pericardial effusion
Code: A B C D
2 4 3 1
2 3 4 1
1 4 3 2
1 3 4 2
4. Match List I with List II and select the correct answer using the code given below the lists:
List I (Emergency drugs) List II (Clinical condition)
A. Amiodarone 1. A-V Block, mobitz type II
B. Adenosine 2. Atrial fibrillation
C. Digoxin 3. Ventricular tachycardia
D. Atropine 4. Paroxysmal supraventricular tachycardia Code: A B C D
1 2 4 3
1 4 2 3
3 2 4 1
3 4 2 1
5. Klebsiella pneumonia has the following characteristics except:
Upper lobes are frequently involved
Pneumatocoele may occur commonly
Empyema is much more common
Lung abscess formation is very uncommon
6. Match List I with List II and select the correct answer using the code given below the lists:
List-I (Disease) List-II (Antigen leading to hypersensitivity pneumonitis)
A. Bagassosis 1. Oak, Cedar, Pine dust
B. Byssinosis 2. Moldy hay
C. Farmer's lung 3. Cotton
D. Wood worker's lung 4. Sugarcane dust
Code: A B C D
4 3 2 1
4 2 3 1
1 3 2 4
1 2 3 4
7. Which one of the following is not likely to be associated with pulmonary fibrosis?
Coal miners' lung
Primary biliary cirrhosis
Asbestosis
Ankylosing spondylitis
8. Which of the following is/are a feature/features of severity in immediate assessment of acute severe asthma?
1. Pulse rate >110 per min
2. Pulsus paradoxus
3. Unable to speak in sentences Select the correct answer using the code given below:
1 only
2 and 3 only
1 and 3 only
2 and 3
9. Cavitating pulmonary lesions can be seen in the following except:
Sarcoidosis
Tuberculosis
Carcinoma of lung
Histoplasmosis
10. A 35 year old 40 kg male patient was diagnosed to be a case of pulmonary tuberculosis. The appropriate conventional regimen of antitubercular drugs would be:
Rifampicin 450 mg Isoniazid 300 mg Pyrazinamide 1500 mg
Rifampicin 600 mg Isoniazid 300 mg Pyrazinamide 1000 mg
Rifampicin 450 mg Isoniazid 200 mg Pyrazinamide 1000 mg
Rifampicin 450 mg Isoniazid 200 mg Pyrazinamide 1500 mg
11. Which of the auscultatory signs is absent in mitral stenosis in the presence of atrial fibrillation?
Mid diastolic murmur
Pre -systolic accentuation
Variable first heart sound
P2 accentuation
12. Which one of the following is not recommended in immediate treatment of acute severe asthma?
Oxygen supplementation
High doses of inhaled B2 -adrenoreceptor agonists
Systemic corticosteroids
Intravenous aminophylline
13. Which one of the following is not a feature of type 2 respiratory failure
pCO2 38 mmHg, and pO2 50 mmHg
pCO2 68 mmHg, and pO2 50 mmHg
Papilloedema
Asterixis
14. Which of the following drugs is not given in dilated cardiomyopathy?
Beta blocker
Calcium channel blocker
Spiranolactone
ACE inhibitors
15. Which of the following features are related to Zollinger Ellison syndrome?
1. Aggressive and refractory peptic ulceration
2. Unregulated gastrin release
3. Beta islet cell tumour of pancreas
4. Diarrhoea present in upto 50% cases Select the correct answer using the code given below:
1 and 2 only
3 and 4
2 and 3
2 and 4
16. In which of the following diseases, primary skin lesions are not seen?
Leptospirosis
SLE
Hepatitis-B
Infectious mononucleosis
17. Which of the following is not a common feature of hypersensitivity pneumonitis?
Raised C-Reaction Protein
Chest X-ray may be normal
Lung biopsy may be diagnostic
Eosinophilia
18. Consider the following statements with regard to duodenal ulcers:
1. They occur most often in the second part of duodenum.
2. Infection with H. pylori and NSAID-induced injury account for the majority of duodenal ulcers.
3. Malignant duodenal ulcers are extremely rare.
4. Eradication of H. pylori has greatly reduced the recurrence rates in duodenal ulcers. Which of the above statements is/are correct?
1 and 3 only
3 and 4 only
2 and 4 only
and 4
19. Carcinoid tumours commonly arise from:
G.cells in pancreas
Argentaffin cells of small intestine
Pancreatic endocrine tumour
Colon polyps
20. Which of the following viral markers signifies the ongoing viral replication in the case of Hepatitis-B infection?
Anti-HBs
Anti-HBc
HBe Ag
HBs Ag
21. The following may result in polyuria except:
Chronic renal failure
Hypoadrenalism
Hypercalcaemia
Lithium carbonate therapy
22. Regarding adult polycystic kidney disease, which one of the following statements is not correct?
Inherited as autosomal dominant with 100% penetrance
Often associated with hepatic cysts
Associated with increased incidence of subarachnoid haemorrhage
Renal cell carcinoma is a frequent association
23. Which of the following is not a feature of chronic renal failure?
Hyperparathyroidism
Osteomalacia
Hyperthyroidism
Decreased 25(OH)2 vitamin D3 level
24. A patient with past history of recurrent headache, presents with irregular, dazzling, enlarging visual phenomena that obstructs vision in the affected region and remains for several minutes. The symptoms are indicative of:
Acute angle closure glaucoma
Retinal detachment
Migraine
Intumescent cataract
25. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (Disease) List-II (Cause)
A. Macrocytic anaemia 1. Iron deficiency
B. Microcytic anaemia 2. Hypothyroidism
C Hemolytic anaemia 3. Vitamin B12 deficiency
D. Megaloblastic anaemia 4. Alpha methyldopa
Code: A B C D
3 1 4 2
3 2 1 4
2 1 4 3
1 4 3 2
26. Haemolysis in G6PD (glucose 6 phosphate dehydrogenase) enzyme deficiency may occur with all of the following drugs except:
Primaquine
Phenacetin
Probenecid
Penicillin
27. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (Blood picture) List-II (Type of Anaemia)
A. Microcytic, hypochromic red cells 1. Vitamin B12 deficiency anaemia
B. Macrocytic, hypochromic red cells 2. Thalassemia major
C Large number of early, intermediate and late erythroblasts 3. Aplastic anaemia
D. Low reticulocyte count 4. Iron-deficiency anaemia
Code: A B C D
1 4 2 3
2 3 4 1
4 1 2 3
3 1 2 4
28. Which of the following conditions does not cause pancytopenia?
Hypersplenism
Aplastic anaemia
Cancer infiltrating the bone-marrow
Haemolysis from G6PD enzyme deficiency
29. Which of the following drugs does not cause oedema?
Growth hormone
Beta blocker
Anabolic steroids
Calcium-channel blockers
30. A patient of hypoglycemia fails to regain consciousness after blood glucose is restored to normal. The complication that carries high mortality and morbidity is:
Cerebral oedema
Lacunar infarct
Post ictal state
Cerebral haemorrhage
31. An adult patient presents with systemic hypertension, renal calculus disease and peptic ulcer disease. Which one of the following is most likely occurrence in this case?
Milk alkali syndrome
Hypervitaminosis D
Primary hyperparathyroidism
Tubulo interstitial renal disease
32. Match List-I with List-II and select the correct answer using the code given below the lists
List-I (types of hyperlipidemia) List-II (feature)
A. Hyperchylomicronaemia 1. Palmar plantar xanthoma
B. Hyperbetalipoproteinaemia 2. Subcutaneous extensive tendon xanthoma
C Type III hyperlipoproteinaemia 3. Eruptive xanthoma over buttocks
D. Familial LPL deficiency 4. Triglyceride level above 1000 mg
Code: A B C D
3 1 2 4
3 2 1 4
4 1 2 3
4 2 1 3
33. Which of the following is least suggestive of poliovirus infection?
Low grade fever and malaise with complete resolution in 2 to 3 days
Biphasic illness with several days of fever, then meningeal symptoms and asymmetric flaccid paralysis 5 to 10 days later
Descending motor paralysis with preservation of tendon reflexes and absent sensation
Failure to isolate a virus from the CSF in the presence of marked meningismus
34. The following conditions can cause interstitial nephritis except:
Infections
Hepatorenal syndrome
Lymphoma
Sarcoidosis
35. Which of the following are characteristics features of tuberculoid leprosy?
1. Type 2 lepra reaction
2. A few lesions with well demarcated edges
3. Early and marked nerve damage
4. Tendency to heal spontaneously Select the correct answer using the code given below:
2 and 3
3 and 4
1 and 4
2 and 3 only
36. Which of the following immunological reactions occurs in Goodpasture syndrome
Type I atopy
Type II cytotoxic
Type III immune complex
Type IV cell mediation
37. Regarding erythema nodosum leprosum, which one of the following is not correct?
It is usually during initiation of treatment
Tender subcutaneous nodules observed
Lymphadenopathy is common
Ophthalmic involvement can occur
38. The most common microorganism known to cause tropical pyomyositis is
Streptococcus viridans
Staphylococcus albus
Klebseilla pneumonia
staphylococcus aureus
39. Following are the common features of Cushing's syndrome except:
Truncal obesity
Osteoporosis
Distal myopathy
Glucose intolerance
40. A farmer presents with history of fever and chills, severe bodyache, headache, conjuctival suffusion and jaundice. He has severe muscle tenderness, leukocytosis and mild uraemia. The most likely diagnosis would be:
Leptospirosis
Typhoid fever
Typhus
Viral hepatitis
41. Consider the following statements regarding falciparum malaria: 1. The mortality rises steeply when the proportion of infected erythrocytes increases above 3 percent. 2. The patient may develop hypoglycemia even when not treated with quinine. Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
42. "Loeffler's syndrome" is characterized by:
Transient, migratory pulmonary infiltrations
Fibrosis in the pulmonary apices
Fibrosis in the base of one or both lungs
Miliary mottling
43. Keyboard operators and typists are especially susceptible to injury of the
Axillary nerve
Median nerve
Ulnar nerve
Radial nerve
44. Which of the following is not a clinical feature of Kwashiorkor?
Bipedal oedema
Visible severe wasting
Low serum albumin
Moon face
45. Match List I with List II and select the correct answer using the code given below the lists:
List I (Clinical features) List II (Deficiency of)
A. Flaky paint rashes of lower extremity 1. Niacin
B. Goose-hump skin lesion 2. Thiamine
C. Confabulation 3. Zinc
D. Dementia 4. Vitamin A
Code: A B C D
1 2 4 3
1 4 2 3
3 4 2 1
3 2 4 1
46. Consider the following:
1. Psoriasis
2. Atopic dermatitis
3. Leprosy
4. Vitiligo PUVA therapy can be used to treat which of the above?
1 and 2 only
2 and 3
2 and 4
3 and 4
47. The cutaneous viral infection which is commonly seen in children and characterized by single or multiple pearly-white skin colored smooth dome shaped papules with central pitting is:
Chicken pox
Herpes zoster
Molluscum contagiosum
Verruca vulgaris
48. Consider the following statements about polyarticular juvenile rheumatoid arthritis:
1. It is more common in girls
2. Five or more joints are affected within the first six months of onset
3. Uveitis occurs in 95% patients
4. Rheumatoid factor may be negative
Which of the statements given above are true
1 and 4 only
2 and 4
3 and 4
2 and 3 only
49. Consider the following statements regarding schizophrenia:
1. Patient feels that other persons put thoughts into his mind
2. Patient feels that he is being punished for his wrong doings
3. He may be in a state of catatonia Which of the statements given above is/are correct?
1 only
2 and 3 only
1 and 3 only
2 and 3
50. Lithium carbonate is employed in the following conditions except:
To treat acute episodes of mania
To prevent recurrence of mania
To prevent depression in bipolar disorders
To prevent depression in unipolar disorders
51. The following conditions can cause protein-losing enteropathy except:
Ulcerative colitis
Irritable bowel syndrome
Celiac disease
Lymphoma
52. Which of the following ocular findings is a component of Foville syndrome?
Lateral gaze palsy
6th N Palsy
3rd N Palsy
Nystagmus
53. The following features are suggestive of Behcet's syndrome except:
Orogenital ulcers
Polyarthritis
Uveitis
Livedo reticularis
54. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (drug) List-II (side effect)
A. Phenytoin sodium 1. Hypothyroidism
B. Para aminosalicylic acid 2. Hepatotoxicity
C Rifampicin 3. 8th nerve damage D. Streptomycin
4. Cerebellar dysfunction
Code: A B C D
4 1 2 3
4 2 1 3
3 2 1 4
2 1 4 3
55. Match List-I with List-II and select the correct answer using the code given below the lists:
List-I (disease state) List-II (clinical feature)
A. Pemphigus vulgaris 1. Acro -osteolysis
B. Psoriasis 2. Brachydactyly
C. Turner syndrome 3. Koebner phenomenon
D. Primary hyperparathyroidism 4. Nikolsky sign
Code: A B C D
1 2 3 4
1 3 2 4
4 2 3 1
4 3 2 1
56. A 10 year old child "blanks out" in class (e.g. stops talking midsentence and then continues as if nothing had happened). During spells there is slight quivering of lips. What is the most probable diagnosis?
Mutism
Autism
Adjustment disorder
Absence seizure
57. A 45 year old man presents with hematuria. Renal biopsy demonstrates a focal necrotizing glomerulitis with crescent formation. The patient gives history of intermittent hemoptysis and intermittent chest pain of moderate intensity. A previous chest X-ray had demonstrated multiple opacities, some of which were cavitated. The patient also has chronic cold like nasal symptoms. What is the most probable diagnosis?
Aspergillosis
Polyarteritis nodosa
Renal carcinoma metastatic to lung
Wegner's granulomatosis
58. A 28 year old woman presented with high grade fever, cough, diarrhea and mental confusion for 4 days. X-ray chest revealed bilateral pneumonitis. Search for etiology will most likely reveal
Streptococcus pneumoniae
Staphylococcus aureus
Legionella pneumophila
Pseudomonas aeruginosa
59. Congenital heart disease associated with pre-excitation is:
Atrial septal defect
Bicuspid aorta valve
Ebstein's anomaly
Patent ductus arteriosus
60. Hockey-stick appearance in echocardiography is a feature of:
Mitral stenosis
Mitral incompetence
Aortic stenosis
Aortic regurgitation
61. Hutchinson sign is a feature of ocular involvement by which of the following viruses?
Herpes simplex
Epstein-Barr virus
Cytomegalovirus
Herpes zoster
62. Well recognised side-effects of prolonged phenytoin use may result in all except:
Hirsutism
Lymphadenopathy
Ataxia
Hypoglycaemia
63. First order neurons in the visual pathway are constituted by:
Bipolar cells
Amacrine cells
Ganglion cells
Rods and cones
64. Level of which hormone is likely to increase after hypothalamic ablation?
Growth hormone
Prolactin
FSH
ACTH
65. A 50 year old patient with signs of peripheral neuropathy is found to have diabetes mellitus. He has no ocular symptoms. When would you refer this patient for retina evaluation?
When he develops ocular symptoms
Immediately
If he needs insulin for blood sugar
Five years after diagnosis
66. Which one of the following tests has the highest chance of detecting HIV infection in a blood donor during the window period?
Demonstration of antibody to HIV by ELISA
CD4 count
P24 antigen detection
Western blot test
67. The following are exotoxin-mediated infections except:
Cholera
Typhoid
Botulism
Tetanus
68. The following tests can be used for diagnosing celiac disease except:
Anti-gliadin antibodies
Anti-nuclear antibodies
Anti-endomycial antibodies
Anti-tissue transglutaminase antibodies
69. Which one of the following is not an early complication of acute myocardial infarction?
Papillary muscle dysfunction
Ventricular septal defect
Pericarditis
Dressler's syndrome
70. Consider the following conditions:
1. Thyrotoxicosis, phaeochromocytoma and acromegaly
2. Haemochromatosis
3. Conn's syndrome (primary hyperaldosteronism)
4. Pancreatic carcinoma
Which of the above may result in secondary diabetes mellitus?
2 and 3 only
2 and 4
3 and 4
2 and 3
71. Consider the following statements: Gastric lavage is contraindicated in children in case of
1. iron poisoning
2. kerosene poisoning
3. corrosive poisoning
4. aspirin poisoning Which of the above statements are correct?
3 and 4
2 and 4
2 and 3 only
1 and 3
72. Consider the following:
1. Visible gastric peristalsis
2. Bilious vomiting
3. Palpable mass
4. Melena
Which of the above is/are the feature/features of infantile hypertrophic pyloric stenosis?
2 and 3
1 and 3 only
2 and 4
4 only
73. A very large ventricular septal defect should be operated
In school going age
Only if CHF is uncontrolled
Before six months of age
Soon after birth
74. A 2 year old boy is being evaluated for severity of malnutrition. The child weighs 7 kg and measures 74 cm in length. Expected (median) weight for height, and height for age for this child are 9 kg and 86 cm respectively. According to WHO classification of undernutrition, which of the following is the correct category for this child?
Wasted, stunted
Wasted, severly stunted
Severly wasted, stunted
Severly wasted, severly stunted
75. Catch-up diet for treatment of severe malnutrition in children should achieve the following:
Calorie 150-220 kcal/kg/d; protein 4-6 g/kg/d
Calorie 125-175 kcal/kg/d; protein 4-6 g/kg/d
Calorie 125-175 kcal/kg/d; protein 2-4 g/kg/d
Calorie 150-220 kcal/kg/d; protein 2-4 g/kg/d
76. Which one of the following is not a feature of vitamin D deficiency rickets?
Decrease in parathyroid hormone level
Decrease in gut calcium absorption
Decrease in renal phosphate excretion
Increase in serum alkaline phosphatase
77. A child presents with moderate fever for two months. On examination, she had moderate anaemia and a few petechia. All the following can be the diagnosis except:
Acute leukemia
Tuberculosis
Typhoid
Juvenile rheumatoid arthritis
78. Which of the following statements is true regarding juvenile chronic myeloid leukemia?
Philadelphia chromosome is negative.
Thrombocytopaenia is uncommon.
The prognosis is better than the adult form of chronic myeloid leukemia.
Single agent chemotherapy with busulfan or hydroxyurea can achieve remission.
79. Consider the following features:
1. X-linked recessive inheritance
2. Atopic dermatitis
3. Low serum levels of IgA Which of the above is/are the characteristic features of Wiskott-Aldrich syndrome?
1 only
1 and 2 only
3 only
2 and 3
80. Lisch nodules are seen in which of the following conditions?
von Recklinghausen's disease
Louis-bar syndrome
Tuberous sclerosis
von Hippel-Lindau syndrome
81. A 5 year old child presented with microcytic hypochromic anaemia. Serum ferritin is low. Which of the following is least likely?
Celiac disease
Thalassemia major
Nutritional anaemia
Paroxysmal nocturnal haemoglobinuria
82. An infant can sit leaning forward on his hands. He bounces actively when made to stand. He laughs aloud and becomes concerned when the mother moves away. What is his most likely age?
12 weeks
16 weeks
22 weeks
28 weeks
83. Match List I with List II and select the correct answer using the code given below the lists:
List I (Association with hepatomegaly) List II (Presentation)
A. Skin lesion 1. Histiocytosis
B. Engorged neck veins 2. Galactosemia
C. Cataract 3. Toxoplasmosis
D. Hydrocephalus 4. Constrictive pericarditis
Code: A B C D
1 4 2 3
2 3 4 1
4 1 3 2
3 4 2 1
84. The most common type of juvenile rheumatoid arthritis is:
Rheumatoid factor positive polyarticular
Rheumatoid factor negative polyarticular
Pauciarticular type
Systemic onset type
85. An 8 year old boy presented to the Emergency Department on the fourth day of fever during a dengue epidemic. He had a mild erythematous rash on his body and no bleeding from any site. His BP was 110/70 mmHg and pulse was 94/minute. Hess test was positive. Dengue serology report is awaited. Platelet count is 30,000/cm3 and PCV: 36%. What is the treatment of choice?
Plenty of oral/ IV fluids and observation
Emergency platelet transfusion to raise platelets above 50,000/ cm3
IV anti-D immune globulin
Give antipyretic and wait for dengue serology report
86. Match List I with List II and select the correct answer using the Code given below the lists:
List I (Antidote) List II (Poison/Drug)
A.Calcium sodium edetate1. Cyanide
B. Sodium nitrite 2. Nitrobenzene
C. Methylene blue 3. Lead
D. Atropine 4. Organophosphate
5. Kerosene
Code: A B C D
1 2 3 4
2 3 4 1
3 1 2 5
3 1 2 4
87. Match List I with List II and select the correct answer using the code given below the lists:
List I (Diseases) List II (Laboratory parameters)
A. Thalassemia major 1. Increased serum iron, decreased TIBC, increased serum ferritin
B. Iron deficiency anaemia 2. Decreased serum iron, increased TIBC, decreased serum ferritin
C. Nephrotic syndrome 3. Decreased serum iron, decreased TIBC, increased serum ferritin
D. Acute iron poisoning 4. Increased serum iron, normal TIBC, normal serum ferritin
Code: A B C D
4 3 2 1
4 2 3 1
1 2 3 4
1 3 2 4
88. A previously well 2 year old boy presents with a brief generalized seizure. There is no past or family history of seizures. On examination, child is alert, active, febrile with axillary temperature of 39.40C. Except for bilateral tonsillar enlargement and congestion, systemic examination is normal. Management at this time may include:
1. Immediate reduction of body temperature
2. Intravenous diazepam and phenytoin, followed by a lumbar puncture
3. Institution of phenytoin for maintenance therapy for at least one year
4. Rectal diazepam every 8 hourly for 2-3 days to reduce the risk of recurrence Select the correct answer using the code given below:
1 and 2 only
1 and 4 only
3 and 4
2 and 4
89. Match List I with List II and select the correct answer using the code given below the lists:
List I (Endocrinological disorders) List II (Results of investigations)
A. Hypothyroidism 1. Increased urinary excretion of catecholamines
B. Cushing's syndrome 2. Increased urinary 17-ketosteroids
C. Pheochromocytoma 3. Hypocalcaemia and hyperphosphataemia
D. Hypoparathyroidism 4. TSH levels are increased and T3, T4 levels are decreased
Code: A B C D
4 2 1 3
4 1 2 3
3 2 1 4
3 1 2 4
90. Match List I with List II and select the correct answer using the Code given below the lists:
List I Clinical presentation) List II (Disease pathology)
A. Extrapyramidal cerebral palsy 1. Stroke
B. Spastic quadriplegia 2. Multicystic encephalomalacia
C. Spastic hemiplegia 3. Periventricular leukomalacia
D. Spastic diplegia 4. Bilirubin encephalopathy
Code: A B C D
3 1 2 4
1 2 3 4
4 3 2 1
4 2 1 3
91. Consider the following pairs: National Park State
1. Keoladeo Ghana National Park ...... Rajasthan
2. Sultanpur National Park ...... Uttar Pradesh
3. Valley of Flowers National Park ...... Himachal Pradesh
Which of the pairs given above is/are correctly matched?
1 only
2 and 3 only
1 and 3 only
2 and 3
92. The Himalayas have snowline at higher altitude compared to that in the Alps mountains. This is because
Himalayas are higher than the Alps
Himalayas face the monsoon winds
Himalayas are located in lower latitudes
Himalayas have denser forest cover
93. The knowledge of genome sequence is important to
1. understand how genes work together in the growth and development of an entire organism.
2. study the regulatory regions in the genome outside the gene that controls expression of genes.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
94. Besides the Sunderbans, mangrove forests are also to be found in
1. Bhitarkanika
2. Godavari delta
3. Pichavaram
4. Kaveri (Cauvery) delta
Select the correct answer using the code given below:
2 and 4 only
3 and 4 only
2 and 3 only
3 and 4
95. Which of the following statements is not correct?
In the preparation of vinegar in the households, dried fruits can be used.
Vinegar making involves fermentation by yeast.
Vinegar is actually acetic acid.
A fruit juice containing or more sugar cannot be made into vinegar in the households.
96. Which one of the following viruses was exploited to create genetically engineered virus "onyx-15", an oncolytic virus to target and eliminate cancer cells?
Parvovirus
Adenovirus
Pox virus
Herpes simplex virus
97. Which one of the following is not included in the Preamble of the Constitution of India?
Secular Republic
Socialist Republic
Federal Republic
Democratic Republic
98. Consider the following milk borne diseases:
1. Brucellosis
2. Listeriosis
3. Salmonellosis
Which of the above can be controlled by pasteurization?
1 only
2 and 3 only
3 only
2 and 3
99. Who of the following is the Chairman of Rajya Sabha?
The Prime Minister
The Speaker of Lok Sabha
The Vice President of India
The President of India
100. Consider the following statements:
1. Fly ash can be added to agricultural soil to enhance its water holding capacity.
2. Fly ash can be used in the manufacture of bricks and blocks for construction purposes. Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
101. "Ecological niche" refers to the
amount of autotrophs available for consumption of the grazing population.
relationship of an animal with the surrounding animals.
position of an animal with reference to its species composition.
positional and functional relationship of an organism in an ecosystem.
102. Which one the following is not required for the formation of photochemical smog?
Oxygen
Oxides of nitrogen
Carbon monoxide
Sunlight
103. The 'Nirbhaya Fund' set up by the Government of India is for:
Ensuring the safety of women
Promoting the financial literacy of rural poor
Promoting Self-Help Groups of women
Providing free education
104. What is "Solar Impulse which was recently in the news?
A Central Government sponsored scheme to promote the production of solar energy
A spacecraft sent by NASA to study a comet moving towards Sun
A project of India in collaboration with NASA to study the impact of solar flares on Earth
A round-the-world flight powered only by the solar energy
105. Consider the following statements:
1. In food preservation by irradiation, ionising rays are used.
2. Irradiation does not affect the colour, odour, taste, pH and levels of vitamin contents in the foods.
Which of the statements given above is/are correct?
1 only
2 only
Both 1 and 2
Neither 1 nor 2
106. Kutch (in Gujarat) has the existence of a large number of salt pans. What could be the most valid reason/reasons for this?
1. Existence of creeks and mudflats
2. Higher evaporation rate
3. Presence of vast intertidal zone Select the correct answer using the code given below:
1 and 2 only
2 only
1 and 3 only
2 and 3
107. Most of the ozone in the atmosphere is concentrated in the:
Ionosphere
Mesosphere
Stratosphere
Troposphere
108. Consider the following:
1. Lactic acid
2. Sorbic acid
3. Sulphurous acid
Which of the above are food preservatives?
1 and 2 only
2 and 3 only
None of these
2 and 3
109. With reference to "DNA Microarray" technology, which of the following statements is/are correct?
1. It helps in identifying the genes involved in a disease by comparing the gene expressions between the tissues from a healthy and an infected person.
2. It allows visualizing the activity of hundreds of genes simultaneously.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
110. Artemesinin is a drug derived from
Plant
Fungus
Rock
Blue-green alga
111. Which of the following can be used to extract heavy metals from water?
1. Aluminium oxide
2. Cellulose
3. Silica
Select the correct answer using the code given below:
1 only
2 and 3 only
1 and 3 only
2 and 3
112. Which one of the following represents the correct sequence of vegetational transitions with increasing latitude?
Rain forest- deciduous forest- coniferous forest
Rain forest- coniferous forest- deciduous forest
Deciduous forest- rain forest- coniferous forest
Coniferous forest- rain forest- deciduous forest
113. Consider the following statements:
1. LED lamps have shorter life span as compared to incandescent bulbs.
2. LED lamps are made by using semi-conductor material.
3. LED lamps are more expensive than conventional sources of lighting.
Which of the statements given above are correct?
1 and 2 only
2 and 3 only
1 and 3 only
2 and 3
114. In India, ecologists consider "sacred groves" very valuable because of their role in
meeting fuelwood and medicinal needs of local people.
protection of biodiversity that has vanished from surrounding areas due to exploitation by man.
stabilization of climate and reduction of global warming.
socio-cultural and religious interactions among traditional communities of different regions.
115. The "Cry1Ac", often in news is
a gene that enables some crop plants to fight pests.
another strain of virus responsible for bird-flue that occurred in China.
a gene used in making the transgenic rice known as "golden rice".
None of these
116. Excessive accumulation of nitrates in water bodies can result in:
1. Proliferation of biodiversity
2. Algal blooms
3. Acidification
Select the correct answer using the code given below:
1 only
2 and 3 only
2 only
2 and 3
117. According to the United Nations Convention on the Rights of the Child, which of the following is/are the right/rights of the children?
1. Right to expression
2. Right to recreation
3. Right to name and nationality
Select the correct answer using the code given below:
1 and 2 only
3 only
2 and 3
None of these is a Right of the children
118. In the context of genetic engineering, which of the following statements is/are correct?
1. Vector mediated recombinant gene transfer can be done from one eukaryote to another eukaryote only.
2. Vector mediated recombinant gene transfer can be done from animal cell to plant cell.
Select the correct answer using the code given below:
1 only
2 only
Both 1 and 2
Neither 1 nor 2
119. What is the importance of a plant named jatropha that is frequently in the news?
It is a wild variety of rice of North-east India rich in vitamin A and iron.
it is a bio-diesel yielding plant that can grow well in areas of low rainfall.
It is a genetically modified pest-resistant potato plant.
It is a highly drought-resistant wild variety of pearl millet adopted for cultivation in dry areas of South India.
120. Gene silencing means a gene which would be expressed under normal circumstances is switched off by cell machinery. Which one of the following cellular components is not involved in gene silencing?
Micro RNA
Double stranded RNA
Ribosomal RNA
Si RNA