Master of Science I (Biotechnology) Examination: Oct/Nov 2016
Semester II (New CBCS)
SLR No. Day
Date Time Subject Name Paper No. Seat No.
SLR SK
105
Thursday
24/11/2016
10.30 AM
to
01.00 PM
Immunology Immune
Techniques
C
VIII
es Instructions: Part- Question 1 is compulsory.
Answer any four questions from Part-II.
Figures to the right indicate full marks.
Answer to the Part I and Part II are to be written in the
same answer book only.
Total Marks: 70
Part- I
Q.1 Rewrite the following sentences by selecting correct answers from given
alternative.
07
Passive Immunisation is done by using
Immune sera Readymade antibodies
Pooled sera All of these
is normal flora of skin.
Staphyloccus epidermidis Staphylococcus aureus
Propionibacterium acne All of these
plays a major role in mounting immune response to
antigens in the blood stream.
Spleen Bone marrow
Lymphnode Thymus
Most abundant class of immunoglobulin in body is
Ig M Ig G
Ig A Ig D
Rhodamine is used in
Immuno-fluoresence ELISA
Agglutination Complement fixation
Class I MHC molecules, peptide binding cleft is formed by
domains.
and 2 and
and and
Rheumatoid arthritis autoimmune disease.
Organ-specific Organ non-specific
Hemolytic None of these
Page 1 of 2
Definitions: 07
Give difference between primary and secondary immune response.
Define Apoptosis and necrosis
Give functions of cytokines
Define anaphylaxis and atopy
Isograft and allogaft
Give examples of Live attenuated and killed vaccines
Give types of antigens.
Part-II
Answer any four of the following.
Q.2 Write an account on mechanism of autoimmunity. 14
Q.3 Write an account on mechanism of T cell mediated immunity. 14
Q.4 Explain cytosolic pathway of antigen processing and presentation. 14
Q.5 Answer any TWO 14
Structure and function of MHC I molecule.
Explain Radioimmunoassay and Immunofluorescence test.
General structure, cultural characters, life cycle, pathogenicity, laboratory
diagnosis prophylaxis of Influenza virus.
Q.6 Answer any TWO 14
Immunogical basics of graft rejection
Explain secondary Iymphoid organs with its function.
Explain mechanism of tumor evasion of immune system.