M.Sc. (Semester II) (CBCS) Examination, 2017
BIOTECHNOLOGY
IMMUNOLOGY AND IMMUNO TECHNIQUES
Day Date: Friday, 28-04-2017 Max. Marks: 70
Time: 10.30 AM to 01.00 PM
N.B. All question of Section I are compulsory.
Answer any four questions from Section II.
Section I
Q.1 Choose the correct alternative and rewrite the sentences: 07
Blood borne antigens are mainly trapped in
Spleen Lymhnode Bone marrow Thymus
Rhodamine B is used in test.
Radioimmunoassay Immune-fluorescence
ELISA Complement fixation
Passive immunization is done by using
Vaccines Toxoids Immune sera Toxins
antibody in called as regain antibody.
IgG IgM IgA IgE
is secondary lymphoid organ.
Spleen Lymphnode Peyer's patch All of these
The smallest unit of antigenecity is
Epitope Adjuvant Hapten Antibody
The first step in the alternate complement activation pathway is

Binding of C1 to antigen-antibody
Binding of C3b to an activator
Binding of C2 to an activator
Binding of antigen to C1
Define the following terms: 07
Isograft and allograft
Properties of cytokines
Enlist chemical barriers of innate immunity
ELISA
Difference between immediate and delayed type of
hypersensitivity
Give any two organ specific autoimmune diseases
Presentation of nonpeptide antigens
Page 1 of 2
Section II
Answer any four of the following:
Q.2 Give structural, morphological, cultural, life cycle and pathogenecity
characters, Lab diagnosis, prophylaxis of HIV virus.
14
Q.3 Explain mechanism of processing and presentation of exogenous antigen. 14
Q.4 Write an essay on principle of antigen and antibody interaction. 14
Q.5 Answer any two of the following: 14
Explain structure of MHC class I molecule.
Explain factors affecting antigenecity.
Mechanism of allograft recognition.
Q.6 Answer any TWO of the following: 14
Traditional vaccines
Alternate complement pathway
Cellular defense mechanisms