Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER VIII • EXAMINATION WINTER • 2016
Subject Code: 2280002 Date: 22-11-2016
Subject Name: Pharmaceutical Technology II
Time: 02:30 pm 05:00 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

What are objectives of enteric coating? Describe polymers used for enteric coating.
06

Discuss in brief following tests for tablet:
Disintegration test
Dissolution test
05

Enumerate defects observed in tablet compression process.
05
Q.2

Write in details about colon drug delivery tablets and its evaluation
06

Write advantages and disadvantages of tablets.
05

Describe biodegradable and non-biodegradable polymers used in microcapsules
05
Q.3

Explain term microcapsule. Discuss in detail phase coacervation phenomena for preparation of microcapsules
06

Write application of extrusion in Pharmacy.
05

Write brief note on importance of microsphere in Pharmacy
05
Q.4

Write on any two: binders disintigrants lubricants
06

Define capsules and write quality control tests on hard gelatin capsules
05

Discuss role of polyethylene oxide and eudragit in melt extrusion
05
Q.5

Write factors affecting on pellet properties.
06

Write a brief note on the size of capsules.
05

Explain extrusion and Pelletization and describe equipment used for it.
05
Q. 6

Define super critical fluid and discuss its pharmaceutical application.
06

Write short note on techniques of SCF and one equipment for SCF processing.
05

Differentiate Primary and secondary packaging with suitable examples.
05
Q.7

Discuss regulatory requirements in pharmaceutical packaging
06

Explain tamper proof packaging
05

Write a brief note on stability aspects of packing.
05