Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code: 2280002 Date: 17/11/2018
Subject Name: Pharmaceutical Technology II
Time: 02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Describe role of diluents in tablet manufacturing. Discuss directly compressible diluents with suitable examples.
06

Enlist types of tablet coating. Describe process variables for pan coating.
05

Describe multistation rotary tablet compression cycle with diagram.
05
Q.2

What are objectives of enteric coating? Describe polymers used for enteric coating.
06

Discuss in brief Pharmacopoeial tests for tablet.
05

Write in details about colon drug delivery tablets and its evaluation.
05
Q.3

Define Capsules. Write the quality control tests on Hard Gelatin
Capsules.
06

Explain various sizes compositions of hard gelatin capsules.
05

Explain the various techniques used in the preparation of microspheres.
05
Q.4

Discuss formulation of soft gelatin capsule shell.
06

Enlist methods of pelletization. Explain cold extrusion technology in detail.
05

Discuss Applications of Extrusion in the pharmaceutical field.
05
Q.5

Explain use of PEO MCC in pelletization.
06

What is SCF? Discuss its pharmaceutical application.
05

Write short note on techniques of SCF and one equipment for SCF processing.
05
Q. 6

Explain the regulatory requirements in pharmaceutical packaging.
06

Explain tamper proof packaging
05

Write on any two: Diluents Disintegrants Binders
05
Q.7

Write a note on ready to use pellets available in market.
06

Write brief note on importance of microsphere in Pharmacy.
05

Differentiate compression consolidation.
05