Exam Details
| Subject | pharmaceutical chemistry iv | |
| Paper | ||
| Exam / Course | b.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | April, 2016 | |
| City, State | gujarat, ahmedabad |
Question Paper
Page 1 of 2
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER IV • EXAMINATION WINTER • 2016
Subject Code: 240003 Date: 24-10-2016
Subject Name: Pharmaceutical Chemistry IV
Time: 10:30 am 01:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Define conformational isomers. What are the different possible conformations of dibromoethane? Which one is more stable? Why?
06
Explain the sequences rule to assign R and S configuration. Draw the possible stereoisomer of 2,3-dichlorohexane.
05
Explain stereoselective and stereospecific reaction.
05
Q.2
Define racemic mixture. Give different method of resolution of racemic mixture.
06
What is polynuclear aromatic compound? Give the chemistry of Naphthalene.
05
What are Grignard reagents? Discuss its utility in organic chemistry with specific example.
05
Q.3
How phenols differ from alcohols? Explain the preparation of Phenol in detail.
06
Explain the role of reagents.
FeCl3 in halogenations of benzene
H2SO4 in nitration of benzene
05
Give the structures of Quinol, Pyragallol, o-Xylene, Resorcinol and Phenanthrene.
05
Q.4
Give conversion of following:
Aspirin from Phenol
Salicylaldehyde from phenol
06
Give two methods for preparation of the functional derivatives of carboxylic acid.
05
Comment on each of the following statements:
Methyl amine is stronger base than ammonia.
Phenol is weak acid.
Benzene is not cyclohexatriene.
05
Q.5
Write a note on Sandmeyer reaction and Hofmann degradation of Amide.
06
What are carbonyl compounds? Explain nucleophilic addition reaction of carbonyl compounds.
05
Explain Cannizaro reaction and Aldol condensation reaction with mechanism.
05
Page 2 of 2
Q. 6
What are amines? How are they classified? Discuss any three general method of preparation and three reactions of amines.
06
Explain the basicity of amines.
05
Discuss various preparation of carboxylic acid. How diethyl malonate is useful in the synthesis of various carboxylic acids?
05
Q.7
How microwaves are useful in organic synthesis? Give its applications and limitations with suitable examples.
06
What is conjugated system? Explain the Michael addition reaction.
05
What do you understand regarding the Nanochemistry? How this technique is involved in organic synthesis?
05
Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER IV • EXAMINATION WINTER • 2016
Subject Code: 240003 Date: 24-10-2016
Subject Name: Pharmaceutical Chemistry IV
Time: 10:30 am 01:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Define conformational isomers. What are the different possible conformations of dibromoethane? Which one is more stable? Why?
06
Explain the sequences rule to assign R and S configuration. Draw the possible stereoisomer of 2,3-dichlorohexane.
05
Explain stereoselective and stereospecific reaction.
05
Q.2
Define racemic mixture. Give different method of resolution of racemic mixture.
06
What is polynuclear aromatic compound? Give the chemistry of Naphthalene.
05
What are Grignard reagents? Discuss its utility in organic chemistry with specific example.
05
Q.3
How phenols differ from alcohols? Explain the preparation of Phenol in detail.
06
Explain the role of reagents.
FeCl3 in halogenations of benzene
H2SO4 in nitration of benzene
05
Give the structures of Quinol, Pyragallol, o-Xylene, Resorcinol and Phenanthrene.
05
Q.4
Give conversion of following:
Aspirin from Phenol
Salicylaldehyde from phenol
06
Give two methods for preparation of the functional derivatives of carboxylic acid.
05
Comment on each of the following statements:
Methyl amine is stronger base than ammonia.
Phenol is weak acid.
Benzene is not cyclohexatriene.
05
Q.5
Write a note on Sandmeyer reaction and Hofmann degradation of Amide.
06
What are carbonyl compounds? Explain nucleophilic addition reaction of carbonyl compounds.
05
Explain Cannizaro reaction and Aldol condensation reaction with mechanism.
05
Page 2 of 2
Q. 6
What are amines? How are they classified? Discuss any three general method of preparation and three reactions of amines.
06
Explain the basicity of amines.
05
Discuss various preparation of carboxylic acid. How diethyl malonate is useful in the synthesis of various carboxylic acids?
05
Q.7
How microwaves are useful in organic synthesis? Give its applications and limitations with suitable examples.
06
What is conjugated system? Explain the Michael addition reaction.
05
What do you understand regarding the Nanochemistry? How this technique is involved in organic synthesis?
05
Other Question Papers
Subjects
- agronomy and forestry of medicinal plants
- anatomy physiology & health education -ii
- anatomy, physiology and health education (aphe)
- applied mathematics (biostatistics)
- basic computer applications
- basic concepts of pharmacology and clinical pharmacy practice
- basics of computer applications
- bioavailability & therapeutic drug monitoring
- bioavailability and therapeutic drug monitoring
- biochemistry
- clinical pharmacy ii
- clinical pharmacy-i
- commerce of herbs and phytoconstitutents
- computer applications in drug discovery
- current advances in novel drug delivery systems
- cyber security
- disaster management
- dispensing pharmacy i
- dispensing pharmacy i and drug store management
- dispensing pharmacy ii and pharma industrial management
- dosage form design –i
- dosage form design- i
- dosage form design- ii
- dosage form design-i
- dosage form design-ii
- drug approval process
- environmental studies
- environmental toxicology and green audit
- food analysis
- forensic pharmacy
- forensic pharmacy-i
- genetic engineering and gene therapy
- green chemistry
- health education and community health
- herbal cosmetics
- hospital and community pharmacy
- hospital management and medical tourism
- hospital pharmacy, community pharmacy & forensic pharmacy
- hospital pharmacy, community pharmacy and dispensing pharmacy-ii
- human anatomy physiology
- human anatomy physiology and health education-ii
- human anatomy physiology-ii
- human anatomy, physiology and health education - i
- innovations in conventional drug delivery system
- instrumental and process validation
- intellectual property rights and patents
- medical writing and coding
- medicinal biochemistry
- nutraceuticals
- pathophysiology
- pharmaceutical analysis ii
- pharmaceutical analysis iii
- pharmaceutical analysis iv
- pharmaceutical analysis-i
- pharmaceutical analysis-ii
- pharmaceutical analysis-iv
- pharmaceutical chemistry – ii
- pharmaceutical chemistry – vi (organic chemistry – ii)
- pharmaceutical chemistry –viii (medicinal chemistry - ii)
- pharmaceutical chemistry iii
- pharmaceutical chemistry iv
- pharmaceutical chemistry vii
- pharmaceutical chemistry-i
- pharmaceutical chemistry-i (inorganic chemistry)
- pharmaceutical chemistry-ii (physical chemistry)
- pharmaceutical chemistry-iii (biochemistry – i)
- pharmaceutical chemistry-iv (organic chemistry-i)
- pharmaceutical chemistry-ix (medicinal chemistry-iii)
- pharmaceutical chemistry-v
- pharmaceutical chemistry-v (biochemistry-ii)
- pharmaceutical chemistry-vi (medicinal)
- pharmaceutical chemistry-vii
- pharmaceutical chemistry-viii
- pharmaceutical chemistry-x
- pharmaceutical chemistry-x (medicinal chemistry-iii)
- pharmaceutical engineering
- pharmaceutical engineering-ii
- pharmaceutical inorganic chemistry
- pharmaceutical marketing management
- pharmaceutical microbiology - i
- pharmaceutical microbiology & biotechnology i
- pharmaceutical microbiology &biotechnology- ii
- pharmaceutical microbiology and biotechnology - ii
- pharmaceutical organic chemistry
- pharmaceutical technology - i
- pharmaceutical technology – i
- pharmaceutical technology- ii
- pharmaceutical technology-i
- pharmaceutical technology-ii
- pharmaceutics-i
- pharmaceutics-ii
- pharmaceutivcal chemistry ix
- pharmacognosy iii
- pharmacognosy iv
- pharmacognosy vi
- pharmacognosy vii
- pharmacognosy vii (herbal formulations & complimentary therapies)
- pharmacognosy-i
- pharmacognosy-ii
- pharmacognosy-iii
- pharmacognosy-iv
- pharmacognosy-v
- pharmacognosy-v (plant bio technology)
- pharmacognosy-vi
- pharmacology -iii
- pharmacology & pharmacotherapeutics-ii
- pharmacology and pharmacotherapeutics - i
- pharmacology and pharmacotherapeutics - iii
- pharmacology and pharmacotherapeutics-iv
- pharmacology-i
- pharmacology-ii
- pharmacovigilance
- pharmacy practice
- physical pharmaceutics-ii
- physical pharmacy
- quality by design (qbd) and process analytical technology (pat)
- regulatory aspects of food and neutraceuticals
- remedial mathematics
- unit operation - i
- unit operation - ii