1 Which enzyme is used by the HIV to form DNA in the host cell?

Endonuclease

Reverse transcriptase

Isomerase

None of the above

2 Mumps is an acute disease caused organism.

HIV

Paramyxovirus

Poliovirus

Hepatitis virus

3 The agents that control the growth of micro-organisms on inanimate objects are referred as

sterilants

antiseptics

antibiotics

disinfectants

4 Preservatives are not to be included in formulations of injectables, administered by route.

Intramuscular

Subcutaneous

Intraocular

Intradermal

5 In the LAL cells are used for the detection of pyrogen.

plasma

lymphocyte

red blood

amoebocyte

5 Nandu remembers that Sachin's birthday is certainly after 18th August but not after 22nd August. Meeta certainly remembers that Sachin's birthday is before 20th August and after 17th of August. It both of them are correct, then when is Sachin's birthday?

19

22

20

21

7 Which one of the following is not a Sexually Transmitted Disease

Gonorrhea

Syphilis

Chancroid

Hepatitis

8 In an autoclave, the sterilization by moist heat is carried out at

160°C for 1 hour

180°C for 30 minutes

121°C and 15 psi pressure for 15 minutes

100°C and 10 psi pressure for 10 minutes

9 The limit test for acid-insoluble ash gives impurities.

inorganic impurities

organic impurities

siliceous impurities

none of the above

10 Which of the following equations is useful in calculating shelf life of Pharmaceuticals in accelerated stability testing?

Noye's Whitney Equation

Gibb's Helmholtz Equation

Arrhenius Equation

Stokes Equation

11 A drug sample, taken by the drug inspector for analysis is sent to

Drug Controller

Chief Inspector

Government Analyst

Public Testing Laboratory

12 Central Register of Pharmacists is maintained by

State Health Ministry

Pharmacy Council of India

State Pharmacy Council

Drug Controller of India

13 The is not included in the First Schedule of DPCO.

rifampicin

paracetamol

aspirin

vitamin C

14 A local anaesthetic agent suitable only for injection is

Tetracaine

Benzocaine

Dibucaine

Procaine

15 In a person infected with HBV, the first virological marker detectable in serum is

HBsA

HBcA

HBeA

Anti HBs

16 Which of the following drug is preferred for prevention and treatment of osteoporosis in postmenopausal women

Raloxifene

Tamoxifen

Ormeloxifene

Toremifene

17 The common carrier, used in vaccine formulation is

Alum

Silica

Calcium carbonate

Mineral oil

18 Which of these cannot be an OTC drug?

Antacids

Antibiotics

Multivitamin syrup

Calcium tablets

19 Find the missing character.


10

11

12

13

20 Vaccine -preventable diseases include all except:

Measles

Typhoid

Japanese Encephalis

AJDS

21 Which of the following is the sole bearer of genetic information (normally)

m-RNA

DNA

r-RNA

Chromatin

22 Which of the following is not a macrolide antibiotic?

Erythromycin

Roxithromycin

Terramycin

Clarithromycin

23 Which of the following will have estrogenic activity


24 Production of which of the following is a characteristic feature of staphylococcal food poisoning?

Neurotoxin

Enterotoxin

Cytotoxin

Endotoxin

25 "Hirudin"

coagulates blood

acts as a heparin substitute and inhibits thrombin

is found in human saliva

is an antidote of heparin

26 As per Gmp guidelines the permitted limit of solid content in water for injection is

100 ppm

1 ppm

10 ppm

0.10 ppm

27 Which of the following blocks Folic acid synthesis?

Sulfanilamide

Carbonylamide

Alkylamide

Acrylamide

28 Any person, aggrieved by any notification, issued regarding Drugs (Price Control) order, may apply to Government for a review within publication in the official gazzette.

10 days

30 days

15 days

6 months

29 One term in the number series is wrong. Find out the wrong term. 10, 50, 500, 5000

5

10

50

5000

30 The purpose of combined drug regimen in tuberculosis is mainly:

To increase the duration of active therapy

To delay the emergence of drug resistance

Promote placebo effect on the patient

To get better effect

31 Arrange the following words in the sequence in which they occur in dictionary:
Brook
Bandit
Boisterous
Baffle
Bright









32 All amino acids used in protein biosynthesis have atleast one asymmetric center except

methionine

arginine

glycine

tyrosine

33 Which of the following personnel is not required for the operation of a blood bank facility?

Medical officer

Registered nurse

Blood bank technician possessing DMLT

Medical social worker

34 Which of the following is referred to as mucosal antibody?

IgG

IgE

IgM

IgA

35 With regard to the use of nitrates, one of the following statements is correct

Tolerance occurs only to the adverse effects and not to the antianginal effect

Nitrates have diuretic effect

Glyceryl trinitrate is given to relieve angina rapidly

Are the drugs of choice in hypertension

36 The active proteolytic enzyme in gastric juice is

Pepsinogen

Pepsin

Trypsin

Gastrin

37 Which of the following compounds is added as a reducing compound to a medium to decrease its oxygen content?

Sodium Taurocholate

Sodium Hydrogen Phosphate

Sodium Cyanide

Sodium Thioglycolate

38 Squeezing of WBCs through the pores of blood capillaries is called as

Passive diffusion

Diapedesis

Chemotaxis

Pinocytosis

39 The most dangerous situation amongst the following is

Rh negative mother bearing her first Rh positive child

Rh negative mother bearing her second Rh positive child

Rh positive mother bearing her first Rh negative child

Rh positive mother bearing her second Rh negative child

40 Erythroblastosis fetalis is a

hemolytic disease of the new-born related to blood groups

type of anaemia

disease related to bone marrow

decrease in white blood cell count

41 Which process leads to a change from liquid to solid form, causing denaturation of proteins?

Precipitation

Coagulation

Agglutination

Centrifugation

42 Choose the figure different from the rest.










43 HLB values of four surfactants are listed below. Which of them is suitable for use as a W/o emulsifier

A -20

B -2.1

C -13.3

D -4.7

44 All of the following are features of Nimesulide except

less oral absorption

weak cox inhibitor

high protein binding

potent anti inflammatory action

45 The plasmids conferring drug resistance are called

R -plasmids

col -plasmids

cryptic -plasmids

degradative plasmids

46 Which of the following compounds will give positive diazotization reaction



47 The double helix model of DNA was proposed by

Watson and Crick

Charagoff

Robinson

Krebs

48 All the drugs are narcotic except:

Opium

Cannabis

Hemp

Cinchona

49 Choose the conclusion which logically follows from the given statement.

Statements: Some men are educated.
Educated persons prefer small families.

Conclusions: All small families are educated.
Some men prefer small families.

If only conclusion follows

If only conclusion follows

If either or follows

If neither nor follows



50 Penicillin G continues to be the first line treatment for following disease, as the causative organism has not developed resistance as yet

Gonorrhoea

Syphilis

Staphylococcal abscess

H. influenza meningitis

51 Which of the following untoward effect is shared by both phenobarbitone and phenytoin

Sedation

Megaloblastic anaemia

Hirsuitism

Gingival hyperplasia

52 are detected by haemagglutination test.

Rabbies

Polio

Influenza

Rubella

53 a causative agent of tuberculosis.

Streptococcus

Staphylococcus

Mycobacterium

Pseudomonas

54 ISO 14000 is concerned with

quality management systems

guidelines for performance of quality management

environmental safety

information -processing system

55 A school planning to start fishing classes, is developing fish ponds on the school grounds. These ponds are dug up with the help of the school children. If 5 children take one hour to dig a pond, how long would it take 12 children to dig 12 ponds of same type?

3 hours

4 hours

5 hours

6 hours

56 As an anticoagulant, aspirin differs from coumarin in which of the following respects?

Being synthetic in nature

Mechanism of action

Route of administration

Therapeutic use

57 Whole human blood is stored at

-20°C

8 -10°C

2

0°C

58 A man said to a lady, "your mother's husband's sister is my aunt." How is the lady related to the man

Daughter

Grand daughter

Mother

Sister

59 Which of the following antidiabetic drug (oral) does not stimulate insulin secretion?

Nateglinide

Repaglinide

Glyburide

Metformin

60 The polyene antibiotics primarily act by

Inhibiting fungal ergosterol synthesis

Creating micropores in fungal cell membrane

Inhibiting fungal DNA synthesis

Disorienting microtubules in fungal cells

61 Polyamide sutures are

natural absorbable

synthetic absorbable

natural nonabsorbable

synthetic nonabsorbable

62 Morphine can be used for all the following therapeutic purposes except:

To relieve the pain of myocardial infarction

To provide sedation and analgesia as a part of 'balanced anaesthesia'

To relieve cancer pain

To relieve pain caused by severe head injury

63 Which of the following steroids is progestogenic



64 How many are there in the following series of numbers which are preceded by 7 but not immediately followed by 9
6795697687678694677695763

One

Two

Three

Four

65 The analysis of biological fluids for sodium, potassium, calcium ions can be done, using:

Flourimetry

Colourimetry

Flame photometry

Potentiometry

66 Which of the following can modify the effect of a drug?

Formulation of the drug

Age, sex, genetic factors

Immune status of the patient

Excipients in the formulation

67 Which one of these sweeteners is carcinogenic

Saccharin

Sucrose

Mannitol

Glycerine

68 Specific agglutinins of ABO system have the following features, except

are gamma globulins

are produced by bone marrow and lymph glands

are present right at birth

are produced in people who do not have the respective agglutinogen in their RBCs

69 Colloid osmotic pressure of blood is mostly contributed by

Blood cells

Albumin

Plasma electrolytes

Fibrinogen

70 Storage temperature for water for injection is

R.T. (Room temperature)

50°C

80°C

37°c

71 Select the pair that has a relationship similar to that in the original pair.










72 Which of the following herbs is considered as valuable 'Nutraceutical'

Senna

Spirulina

Vasaka

Bael

73 Amit goes 30 metres North, then turns right and walks 40 metres, then again turns right and walks 20 metres, then again turns right and walks 40 metres. How many metres is he from his original position?

0

10

20

40

74 Pointing to a lady in the photograph, Dev Anand said, "This woman is my sister's father's son-in-law's wife". How is Dev Anand related to the woman

Mother

Sister

Wife

Cannot be determined

75 Which of the following metal binding agents inhibits the growth of anaerobic bacteria, except Lactic acid bacteria

Sodium citrate

Sodium azide

Sodium nitrate

Sodium acetate

76 Neutralization test is generally used for the serodiagnosis of infections.

viral

bacterial

fungal

protozoan

77 Which one of the following statements about eosinophils is incorrect?

Present numerously in blood

Are weak phagocytes

Shows chemotaxis

Releases modified lysosomes

78 For the Assertion and Reason given below, choose the correct alternative from the following answer options.

Assertion Leaves of plants are green.
Reason Plants contain chromoplasts the green pigment.

Both and are true and is the correct explanation of

Both and are true but is not the correct explanation of

is true but is false

is false but is true

79 Widal test is used for diagnosis disease.

dysentery

tuberculosis

typhoid

leprosy

80 Essential Drugs are those which should be available in every

Chemist shop

Primary health centre

Private hospital

Nursing home

81 The most commonly used vector in Recombinant DNA technology is

B. Subtilis

E. Coli

B. Megaterium

P. Aemginosa

82 The magic remedies Act was passed and enforced in the year

1954

1919

1930

1940

83 What is chelating capacity of one hundred milligram of desferrioxamine in terms of milligrams of iron

4.5

8.5

6.5

10.5

84 A goes 4 km South, then 8 km West, then 6 km North, then 8 km East and then 2 km South. How far is A from the starting point?

2 km

1 km

0 km

3 km

85 The cultivation of opium poppy and production of opium are to be supervised by

Narcotics Inspector

Drug Controller

Narcotics Commissioner

Narcotics Consultative Committee

86 UV spectroscopy is not useful for identification of

Compounds with double bonds

Compounds with conjugated double bonds

Poly-aromatic compounds

Alkanes

87 If a drug is not labelled in prescribed manner, it is known as

Spurious drug

Misbranded drug

Genuine drug

Adulterated drug

88 Which of the following vaccines is included under Universal Immunization Programme but not under Indian Immunisation Schedule

Measles

Hepatitis B

Hi B

Tetanus

89 The molecular weight of any organic compound can be determined by spectrometry.

IR

UV

NMR

MS

90 Choose the conclusion which logically follows from the given statement.
Statement All scientists working in America are talented. Some Indian scientists are working in America

Conclusion:
None of Indian scientists is talented
Some talented Indian scientists have migrated to America
All talented scientists are Indians
Some Indian scientists are talented

The conclusion(s) correctly drawn is/are:

B and C

A only

B and D

B only

91 Laminar airflow is used for

aseptic technic

incubation

fermentation

detection of specific gravity

92 Aseptic filling of injections is to be carried out in facility complying to grade

A

B

C

D

93 Which of the following vaccines is used as an adjuvant in immunotherapy of cancer?

BCG

DPT

TAB

Mumps

94 The medicinal includes

Tincture of

Aerial parts of tree

Extract of

All the above

95 To which of these wavelengths is the highest bactericidal efficiency of Ultra Violet Rays attributed

2050 °A

2650 °A

3250 °A

3850 °A

96 The missing number in the given figure


15

13

12

10

97 Four groups of letters are given. Three of theql are alike in a certain way, while one is different. Choose the odd one.

BD

MP

NQ

HK

98 Advertise;mentJor a clrug, claiming cure for a disea!?e is prohibited for the following diseases, except:

Cancer

Malaria

HIV

Cough and Cold

99 Which of the following is not an indication for imipramine?

Enuresis in school children

Phobia

Temporal lobe epilepsy

Trigeminal neuralgia

100 Which of the following information is not required to be present on the label for whole human blood

The donor classification as 'Voluntary Donor' or 'Replacement Donor'

The nature and percentage of anticoagulant

The haemoglobin content

Results of test for freedom from malarial parasite

101 UV-Radiation lies in the range of

400-650 nm

200-400 nm

900-1200 nm

1400 nm and more

102 Which of the following ACE inhibitQr has sulfhydryl group?

Captopril

Enalapril

Lisinopril

Perindopril

103 Which one of the following perspectives about platelets is likely to be untrue?

Non-nucleated

Formed in bone marrow

Can reproduce

Liberate platelet factor

104 Following herb is considered as valuable nutraceutical

Sanna

Ginseng

Cinchona

Bael

105 Which of the following counting chambers is used to perform Direct Microscopic Count of bacteria with moderate accuracy

Newbar

Petroff -Hausser

Chamberland

Hausser -Newbar

106 Which of the following pair regarding antidote and its indication for use in poisoning is not correct?

Fluoride: Calcium

Fomepizole: Methanol

Flumazenil: Benzodiazepines

Phentolamine: Physostigmine

107 If means means means and x means then
36 x 12 4 6 2 3

2

18

42

6 1/2

108 The position of absorption band in IR spectrum due to hydroxyl group lies

3200 cm-1 -3600 cm-1

1600 cm-1 -2000 cm-1

2300 cm-1 -2600 cm-1

300 cm-1 -600 cm-1

109 All of the following statements about chancroid are true, except

Multiple painful ulcers

Prolong incubation period months)

Suppurative inguinal bubo

Caused by haemophilus ducreyi

110 Which of these is not a standards institution?

BIS

ISO

ASTM

IDMA

111 If GIVE is coded as 5137 and BAT is coded as 924, how is GATE coded

5427

5724

5247

2547

112 The site of protein synthesis in cell is

Ribosomes

Cell-membrane

Mitochondria

Nucleus

113 Choose out the odd one.

Lake

River

Winds

Current

114 GMP guidelines for Ayurvedic Medicines are prescribed D and C Act.

Schedule T

Schedule M

Schedule V

Schedule P

115 Aspirin poisoning includes the following symptoms except:

Dehydration

Hypothermia

Metabolic acidosis

oliguria

116 Which of the following drug act by inhibiting GP IIb/IIIa?

Ticlopidine

Abciximab

Clopidogrel

Dipyridamole

117 The quantitative analysis by UV spectrophotometry is based on

Fick's law

Gauss law

Beer Lambert's law

Charles law

118 The warning "If irritation persits or increases, discontinue use and consult physician" is mentioned on labels of

Ophthalmic products

Skin creams

Hair grooming preparations

Antidandruff products

119 Test micro-organism used for microbiological assay of Vitamin B12 is

lactobacillus leichamannii

lactobacillus casei

lactobacillus viridescens

lactobacillus plantarum

120 Tautomerism is examplified by



121 Which of the' following statements is correct about Thromboxane A2 (TxA2)

TxA2 causes platelet aggregation

TxA2 is metabolised to prostacyclin

TxA2 is directly inactivated by aspirin binding

TxA2 is PGI2

122 The HPTLC system comprises of all the parts, except:

Scanner

Applicator

Chamber

Potentiometer

123 Which of the following is not a method ofsterilization?

Autoclaving

Pasteurization

Tyndallization

treating with a bactericide

124 All the following drugs are 'essential anti-malarial drugs',

Quinine

Chloroquine

Artesunate

Primaquine

125 Measures to control "AIDS" include all

not donating blood

distribution of condoms by PHC's

protection during each sexual contact

disposal of blood and blood-products safely and hygeinically

126 The person in charge of State Drug Laboratory is

Drug Controller

Government Analyst

Drug Inspector

Chief Chemist

127 Vaccines and Sera are included in D and C Act.

Schedule C

Schedule G

Schedule FF

Schedule X

128 In patients with renal insufficiency, the adjustment of dose is not critical for

Ciprofloxacin

Norfloxacin

Pefloxacin

Ofloxacin

129 pathogenic organism is Acid -Fast bacillus.

Salmonella

Vibrio cholerae

Shigella flexneri

Mycobacterium tuberculosis

130 Type I hypersensitivity reactions are usually mediated by

IgE antibodies

IgG antibodies

IgM antibodies

Macrophages

131 'Rideal Walker Co-efficient' (RW-Coeff.) is important for labels of

Dettol

Talcum powder

Cat-gut

Odomos

132 What is the minimum number of straight lines that is needed to construct the figure?


11

13

15

21

133 DOPP test is used for the evaluation of efficiency of

Membrane Filters

Seitz Filters

G 3 Filters

HEPA Filters

134 Choose the most suitable reaction to the given situation.
If in the examination hall, you find that the question paper is too tough to be answered satisfactorily by you, the best thing to do for you is to

tell the examiner that the questions are out of course.

provoke the candidates to walk out of the examination hall.

try to know something from your neighbour

try to solve the questions as much as you know with a cool head

135 Schedule V of D and C Act gives the standards for

Patent and proprietory medicines containing vitamins

Cosmetic preparations

Disinfectant fluids

Contraceptives

136 Charaffs rule of base equivalence for DNA states that:

A T U G

T G T C

A C T G

C A D E

137 Choose the one which is different from the rest three.

7

15

31

57

138 letter will replace the question mark
J L N P R T

S

U

V

W

139 Which of the following pollutants produces pulmonary oedema and death

Carbon dioxide

Carbon monoxide

Sulfur dioxide

Ozone

140 Multiple, superficial, grouped erosions over genitals are due to

Chancroid

Syphilis

Condyloma accuminata

Herpes genitalis

141 Vitamin.K is necessary for

prevention of rickets

formation of prothrombin

prevention of night blindness

formation of DNA

142 Which of the following pair indicate isomers



143 HIV infection predominant in India, is

HIV la

HIV Ib

HIV lc

HIV Ie

144 Which of the following is not a type of Industrial Intellectual property

Patents

Trademarks

Copyright

Industrial designs

145 Find out which of the alternative indicates the correct relationship between the given words:
Triangle, Four sided figure, Square.



146 Which of the following does not belong to the 5 -alpha series?

Androgens

Estrogens

Progesterone

Bile acids

147 Baker's yeast is the common name for

Bacillus subtilis

Lactobacillus acidophilus

Saccharomyces cerevisiae

Candida albicans

148 DHO (District Health Officer) is responsible for enforcement of one of the following programmes

NAMP -National Anti-malaria Programme

NLEP -National Leprosy Eradication Programme

NMHP -National Mental Health Programme

NWSS -National Water Supply and Sanitation

149 Which one of these antileprotic drugs possesses anti inflammatory action?

Dapsone

Clofazimine

Rifampicin

Ethionamide

150 Rideal Waltz Co-efficient is to be stated on labels of

Antibiotic preparations

Disinfectant fluids

Sunscreen preparations

Shampoo formulations