Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm SEMESTER VI- • EXAMINATION WINTER-2016
Subject Code: 260003 Date:21/10/2016
Subject Name: Pharmaceutical Chemistry-VII (Biochemistry)
Time: 2.30 PM to 5.30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write about biosynthesis and utilization of ketone bodies.
06

Give detailed account on enzymes involved in biological oxidation
05

Explain Urea cycle with its metabolic disorders.
05
Q.2

Discuss purine biosynthesis. Explain inhibitors of purine synthesis
06

Write a note on replication of DNA in prokaryotes
05

Write a note on Genetic code
05
Q.3

Define protein synthesis. Write a note on inhibitors of protein synthesis
06

Write a note on chromatography
05

Discuss biosynthesis of Heme
05
Q.4

Discuss Transamination and Deamination reactions
06

Write a short note on RNA
05

Define bioenergetics and discuss concept of free energy
05
Q.5

What is PCR? Write a note on PCR its significance
06

Give details about electrophoresis techniques.
05

Write a note on β-oxidation of fatty acids.
05
Q. 6

What is operon? Explain Lac operon
06

Explain in brief metabolism of sulphur containing amino acids.
05

Discuss in detail cholesterol biosynthesis.
05
Q.7

Discuss about Transcription process in prokaryotes
06

Discuss metabolism of water
05

Discuss biochemical role and deficiency symptoms of calcium.
05