Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER VII • EXAMINATION WINTER • 2016
Subject Code: 270002 Date: 19-11-2016
Subject Name: Pharmaceutical Technology- I
Time: 10:30 am 01:30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write a note on pyrogens and its testing.
06

Give the different types of glass with their tests.
05

Describe pre-filling treatment of parentral containers.
05
Q.2

Write a note on Emulsifying agents Suspending agents.
06

Write a short note on vehicles solvents used in liquid dosage forms.
05

Outline manufacturing procedure of liquid orals.
05
Q.3

Define Aerosols. Give a brief account of propellants.
06

How will you evaluate aerosols?
05

Write pharmaceutical applications of aerosols.
05
Q.4

Differentiate creams, ointments and gels with their specific advantages. Write a short note on suppository bases.
06

Discuss the evaluation parameters for semisolid formulations.
05

Explain mechanisms of drug penetration through skin.
05
Q.5

Discuss pharmaceutical testing of aerosols.
06

Enlist components of aerosol. Explain propellants in detail.
05

Describe quality control tests for parenterals.
05
Q. 6

Discuss the factors affecting drug release from semisolids.
06

What is significance of HLB value? Classify emulsifying agents.
05

Differentiate S.V.P and L.V.P.
05
Q.7

Comment: Ophthalmic product should be used within one month after opening the cap. Write in brief on formulation of ophthalmic dosage form.
06

Write a short note on W.F.I.
05

Enumerate evaluating parameters of emulsions.
05