Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code:2270002 Date: 17/11/2018
Subject Name: Pharmaceutical Technology I
Time:10:30 AM TO 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Comment on the following:
1. Liquid paraffin is oil of choice for oily injections and parenteral emulsions.
2. Cyro-protectants are to be added in freeze dried products.
3. I.V. is most popular route of parenteral administration.
06

What are clean rooms? Discuss the standards for clean rooms. Enumerate criteria for environmental monitoring of clean rooms.
05

Write a note on FFS technology.
05
Q.2

Write importance of the following in liquid dosage form: Stabilizer,
Preservative and vehicle/solvent.
06

Explain in brief: tincture, extract, infusion with example.
05

Describe the evaluation of suspensions and emulsions.
05
Q.3

Give the ideal requirements of the semisolid bases. Discuss the evaluation parameters of semi-solid formulations.
06

Classify routes of drug penetration through skin. Discuss factors influencing penetration of drugs through skin.
05

Explain in brief displacement value. Enumerate ideal characteristics of suppository bases.
05
Q.4

Describe filling techniques of aerosols.
06

Enlist various containers used for aerosol. Explain various types of actuators and valve used in aerosol.
05

Describe in detail quality control for pharmaceutical aerosol products.
05
Q.5

What are sunscreen preparations? Discuss their formulation and evaluation in brief.
06

Differentiate vanishing cream and cold creams.
05

Write a brief note on baby care products.
05
Q. 6

Describe in short: Parenteral nutrients, freeze dried parenteral products.
06

Discuss storage and quality control test for WFI.
05

Write a short on prefilled syringes.
05
Q.7

Enumerate different type of record maintain in pharmaceutical company as per GMP. Write short note on batch manufacturing record.
06

Discuss the premises facility requirements as per GMP.
05

Write a short note on SOP.
05