DISTANCE EDUCATION
M.Sc. (Chemistry) DEGREE EXAMINATION, MAY 2016.
ORGANIC CHEMISTRY I
(2008 Onwards)
Time Three hours Maximum 100 marks
Answer any FIVE questions.
All questions carry equal marks.
20 100)
1. Is cyclo pentadienyl cation aromatic? Justify
your answer.
Explain, why 6-trinitro-N,N-dimethylaniline
is more stronger base than 2,4,6-trinitro aniline.

Which ring is azulene is reactive towards
electrophilic substitution? Give reason.
Identify the products formed when toluene is
chlorinated in the presence and in the absence
of halogen carrier.
Discuss the characteristic features of alternant and
non-alternant hydrocarbons.
What are nitrenes? How are they generated?
Indicate any one of its reactions?
Give a brief account of Hammond postulate.
2. What are the methods employed to detect hydrogen
bonding?
Explain the use of stereo chemical studies in
determining the reaction mechanism.
Write down the SN1 mechanism and discuss the
solvent and substrate effect.
Sub. Code
11
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3. Give the mechanism for the following reaction,
Gattermann Koch formylation
Friedel-Craft alkylation.
Hydroboration is a regio-specific reaction Explain.

Write note on Bredt's rule.
Explain the term retro-grade aldol condensation.
4. Electrophilic addition to the unsaturated double
bond is stereo specific reaction Explain.
Write notes on Hofmann and Saytzeff rule.
Discuss the mechanism for the following reaction
Perkin reaction
Cannizzaro reaction.
5. Write notes on stereo selectivity and chemo
selectivity.
Discuss briefly about the bio synthesis of alkaloids.

Write note on pyrolytic cis-elimination.
6. How would you elucidate the structure of Zingiberene?

7. Write the synthesis of the following compounds.
Flavone
Indole.
What happens when morphina is distilled with zinc
dust?
Distinguish between DNA and RNA.
Distinguish between -amylase and amylopectine.

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8. Write notes on end group analysis of peptide.
What are enzymes? What are its characteristics?
Write down the functions of oxytocin.