Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B.PHARM SEMESTER EXAMINATION -WINTER 2018
Subject Code:2220002 Date: 13/12/2018
Subject Name: Pharmaceutical Chemistry-II (Physical Chemistry)
Time:02:30 PM TO 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make Suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

What is Refractive Index? Give its importance in Pharmacy. Enlist the factors affecting refractive index.
06

Define: Viscosity and fluidity. Describe principle of Ostwald's viscometer.
05

Discuss the measurement of surface tension by drop formation method.
05
Q.2

Define: Fluorescence, Phosphorescence and Chemiluminescence.
06

Draw a Jablonski diagram explain consequences of Light absorption.
05

Define: photochemistry. Explain Lambert Beer law.
05
Q.3

Explain in detail Debye-Huckel theory.
06

Define Enlist Colligative Properties. Explain any two in detail.
05

Define: Molarity and Normality. Explain Henry's law in brief.
05
Q.4

State explain first law of Thermodynamics with various modifications.
06

Enlist various methods for the determination of order of reaction.
05

Define enthalpy. How enthalpy of a chemical reaction can be calculated?
05
Q.5

Differentiate between: Adsorption and Absorption
Physical adsorption and Chemical adsorption.
06

Explain in detail Langmuir Adsorption isotherms.
05

Discuss applications of adsorption in pharmacy.
05
Q. 6

State and explain phase rule. Describe phase diagram of water.
06

Derive Reaction rate constant half-life for first order reaction kinetics.
05

Write a note on "The Carnot Cycle".
05
Q.7

State and explain Raoult's law of dilute solution. Discuss deviation of real solution from the Law.
06

Write a note on Parachlor.
05

Discuss Acid-base Enzyme Catalysis in detail.
05