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Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER- II • EXAMINATION SUMMER 2017
Subject Code: 2220002 Date: 07/06/2017
Subject Name: Pharmaceutical Chemistry-II (Physical Chemistry)
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

What is Surface tension? Derive equation to determine surface tension by capillary rise method.
06

Define following terms:
1. Viscosity
2. Optical activity
3. Partition Coefficient
4. Conductance
5. Refractive Index
05

Define parachor and dipole moment. Give their application in molecular structure determination.
05
Q.2

Give basic classification of solutions. Give detail difference between ideal and real solutions.
06

Define colligative properties. Explain Depression of Freezing point.
05

A solution containing 2.44 gm of solute dissolved in 75 gm of water boiled at 373.413 K. Calculate molecular mass of solute. (kb of water is 0.52 Boiling point of pure water 100°C)
05
Q.3

Define Adsoption isotherm. Write a short note on Langmuir adsoption isotherm.
06

Give detail difference between physical and chemical adsoption.
05

Write a short note on Henry's law.
05
Q.4

Derive equation of rate of reaction and half life for first order kinetics.
06

Write a short note on second order reaction.
05

50% first order reaction is completed in 23 minutes. Calculate the time required to complete 90% of the reaction.
05
Q.5

Explain difference between:
1. Homogeneous and heterogeneous catalysis.
2. Order of reaction and molecularity.
3. Adsorption and Absorption.
06
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Write a short note on theories of catalysis with mechanism.
05

Define:
1. Promoter
2. Autocatalysis
3. Heat of combustion
4. Heat of Neutralisation
5. Degree of freedom
05
Q. 6

Define thermodynamics. State and explain first law of thermodynamics with various modification and limitations.
06

Write a short on various thermodynamic processes.
05

Give equation of work for reversible expansion of ideal gas. Calculate work done when one mole of an ideal gas at 25°C is allowed to expand reversibly at constant temperature from a volume of 10 liters to 20 liters.(R=8.31 J K-1 Mol-1)
05
Q.7

Write a short note on one-component system with example.
06


Explain Jablonski diagram for various photochemical processes
in detail.
State and explain Lambert-Beer's law of Photochemistry.
05
05