Exam Details
| Subject | cellular and molecular pharmacology | |
| Paper | ||
| Exam / Course | m.pharm | |
| Department | ||
| Organization | Gujarat Technological University | |
| Position | ||
| Exam Date | May, 2018 | |
| City, State | gujarat, ahmedabad |
Question Paper
Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Ph. SEMESTER- I EXAMINATION SUMMER-2018
Subject Code: 910103 Date: 05/05/2018
Subject Name: Cellular and Molecular Pharmacology
Time: 02:30PM TO 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Enlist various transport mechanism across cell membrane. Explain in detail about carrier-mediated transport mechanism.
06
Discuss all types of drug antagonism with suitable examples.
05
Write a note on Muscarinic receptors location, types, signal transduction and agonist antagonists.
05
Q.2
Classify adrenergic receptors. Explain signal transduction pathways of adrenergic receptor in heart muscle.
06
Discuss various diseases resulting from receptor malfunction.
05
Write a note on types and modulators of calcium channels.
05
Q.3
Classify dopamine receptors. Explain in brief about their location and signal transduction mechanism.
06
Discuss signal transduction mechanisms by G-protein coupled receptor in detail.
05
Write a note on various theories of drug-receptor interaction.
05
Q.4
Classify the following receptors and describe their signal transduction mechanism citing suitable examples as agonist and antagonist:
Endothelin Serotonin
06
Explain the role of Nitric oxide in pathophysiology of various diseases.
05
Discuss importance of Radio-ligand binding studies in detail.
05
Q.5
Enlist excitatory neurotransmitters. Write in detail about NMDA receptors with suitable agonists and antagonists.
06
Discuss therapeutic significance of voltage gated sodium channels.
05
Write a note on pathophysiological role of leukotrienes.
05
Q. 6
Define apoptosis. Discuss signaling pathways that result in apoptosis.
06
Explain the role of stress induced genes in aging and write in brief about anti-aging drugs.
05
Write a note pathological role of bradykinin.
05
Q.7
Define gene therapy. Discuss applications of gene therapy in detail.
06
Explain the role of TNF-α in various immunological and inflammatory disorders.
05
Write a short note on Purines.
05
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Ph. SEMESTER- I EXAMINATION SUMMER-2018
Subject Code: 910103 Date: 05/05/2018
Subject Name: Cellular and Molecular Pharmacology
Time: 02:30PM TO 05:30PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1
Enlist various transport mechanism across cell membrane. Explain in detail about carrier-mediated transport mechanism.
06
Discuss all types of drug antagonism with suitable examples.
05
Write a note on Muscarinic receptors location, types, signal transduction and agonist antagonists.
05
Q.2
Classify adrenergic receptors. Explain signal transduction pathways of adrenergic receptor in heart muscle.
06
Discuss various diseases resulting from receptor malfunction.
05
Write a note on types and modulators of calcium channels.
05
Q.3
Classify dopamine receptors. Explain in brief about their location and signal transduction mechanism.
06
Discuss signal transduction mechanisms by G-protein coupled receptor in detail.
05
Write a note on various theories of drug-receptor interaction.
05
Q.4
Classify the following receptors and describe their signal transduction mechanism citing suitable examples as agonist and antagonist:
Endothelin Serotonin
06
Explain the role of Nitric oxide in pathophysiology of various diseases.
05
Discuss importance of Radio-ligand binding studies in detail.
05
Q.5
Enlist excitatory neurotransmitters. Write in detail about NMDA receptors with suitable agonists and antagonists.
06
Discuss therapeutic significance of voltage gated sodium channels.
05
Write a note on pathophysiological role of leukotrienes.
05
Q. 6
Define apoptosis. Discuss signaling pathways that result in apoptosis.
06
Explain the role of stress induced genes in aging and write in brief about anti-aging drugs.
05
Write a note pathological role of bradykinin.
05
Q.7
Define gene therapy. Discuss applications of gene therapy in detail.
06
Explain the role of TNF-α in various immunological and inflammatory disorders.
05
Write a short note on Purines.
05
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Subjects
- advanced medicinal chemistry
- advanced organic chemistry-i
- advanced organic chemistry-ii
- advanced pharmacology ii
- advanced pharmacology-i
- advances in drug delivery system
- advances in pharmacology
- applied pharmacotherapeutics - ii
- applied pharmacotherapeutics-i
- audits and regulatory compliance
- biological evaluations & clinical research
- cellular and molecular pharmacology
- clinical and hospital pharmacy
- clinical pharmacy practice
- clinical research and pharmacy practice
- clinical research and regulatory affairs
- clinical research regulations
- cosmetic and cosmeceuticals
- documentation and regulatory writing
- drug design and discovery
- drug regulation and regulatory authority
- experimental design and patents
- global regulatory requirements
- gmp, glp and validation
- good manufacturing and good laboratory practice
- good manufacturing practice and process validation
- good regulatory practices
- hazards and safety management
- industrial pharmacy practice
- modern analytical techniques
- modern pharmaceutical analysis
- novel drug delivery system part-i
- novel drug delivery system-ii
- pharm. management -ii
- pharmaceutical analysis ii
- pharmaceutical and cosmetic analysis
- pharmaceutical formulation and development
- pharmaceutical formulation development and biopharmceutics
- pharmaceutical manufacturing technology
- pharmaceutical production management & technology
- pharmaceutical regulatory affairs
- pharmacological and toxicological screening methods-i
- pharmacological and toxicological screening methods-ii
- pharmacometrics and methods of biological evaluation of drugs
- pharmacotherapeutics
- principles of biopharmaceutics& pharmacokinetics
- product development and technology transfer
- quality control & quality assurance
- quality control and quality assurance
- quality management system
- regulatory affairs - i
- regulatory affairs and new drug applications
- regulatory aspects of hebbal and biologicals
- research methodology
- validation and product development