Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
M. Pharm. SEMESTER I EXAMINATION SUMMER 2017
Subject Code: 910203 Date: 01/05/2017
Subject Name: Advances in pharmacology
Time: 10:30 AM to 01:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write mechanism of action of following drugs: (any three)
i. Cotrimoxazole ii. Fluoroquinolones iii. Gancyclovir iv. Dapsone
06

Discuss in brief the Pharmacological actions of 5-HT.
05

Write in brief about Macrolides.
05
Q.2

Classify Penicillins. Describe the Pharmacology of Ampicillin.
06

Write a note on neuromuscular blockers.
05

Classify drugs used in Leprosy. Write a note on Clofazimine.
05
Q.3

Write a short note on Anticholinesterases.
06

Classify anticancer drugs. Discuss antibiotics used as anticancer drugs.
05

Write a note on Leukotrienes.
05
Q.4

Classify H1 antagonists. Discuss their pharmacological actions and adverse effects.
06

Classify adrenoceptor antagonists. Discuss the pharmacology of Tamsulosin.
05

Enumerate antifungal agents. Write a note on Amphotericin-B.
05
Q.5

Explain DOTS therapy. Discuss the use of Isoniazid in tuberculosis.
06

Explain in brief mechanisms of resistance to antibiotics.
05

Explain mechanism of action, therapeutic uses and adverse effects of aminoglycosides.
05
Q. 6

Write a note on hormonal agents used in Cancer.
06

Classify antimalarial agents emphasizing on their mechanism of action and stage of parasite affected.
05

Write a note on anthelmentics.
05
Q.7

Explain mechanism of action, antimicrobial spectrum and dose related toxicity of tetracyclines.
06

Classify immunosuppresants. Explain in detail calcineurin inhibitors.
05

Discuss the pharmacotherapy of Syphilis.
05