Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B.Pharm SEMESTER III • EXAMINATION SUMMER 2017
Subject Code: 230003 Date: 12/06/2017
Subject Name: Pharmaceutical Chemistry III
Time: 02:30 PM to 05:30 PM Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Write a note on Kjeldahl's method for Nitrogen estimation.
06

What is Bonding and Anti-bonding orbitals? Explain in detail.
05

What are different methods used to determine Molecular Weight of organic compound? Discuss any two methods in detail.
05
Q.2

Define Hybridization. Explain in detail Hybrid Orbitals with examples.
06

Write a note on Intermolecular and Intramolecular forces.
05

How Hyperconjugation and Resonance differ from each other? Discuss with examples.
05
Q.3

What are relative Intermediates of Carbon? Describe in detail about Carbocation.
06

Explain the Electrocyclic Cycloaddition reaction.
05

Write a note on Sigmatropic reaction.
05
Q.4

Explain the mechanism of Halogeanation for alkane.
06

Differentiate E2 and E1 mechanism of elimination.
05

Give general methods for the preparation of Alkyne and Dienes.
05
Q.5

Outline difference between SN1 and SN2 reactions of Alkyl halides.
06

Give preparations and reactions of Alkyl Halides.
05

Classify Alcohol and write a note on Dehydration of Alcohol.
05
Q. 6

Write a note on Williamson's synthesis of ether.
06

What are epoxides? Give the methods for preparation of epoxides.
05

Write a note on Diels Alder reaction.
05
Q.7

Define Petroleum, Molecular formula and Empirical formula with suitable examples.
06

Explain in details about Atomic and Molecular Orbitals and Bond Dissociation Energy.
05

Discuss Electronegativity and Polarity of Bond and molecule.
05