B. Pharmacy II Year I Semester (Suppl.) Examination, April 2018
Subject: Pharmaceutical Analysis I (Chemical Analysis)
Time: 3 Hours Max.Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 What is a primary standard? Explain briefly giving examples.
ii) Explain accuracy, precision, error and linearity with examples.
OR
What is calibration? Why calibration of glassware is necessary? How do you
calibrate a burette?
ii) Explain about methods of expressing concentration.
2 Explain about different theories of acid and base.
ii) Write a note on common ion effect.
iii) Calculate the pH of 0.05 M solution of sodium acetate.
(The dissociation constant of acetic acid is 1.8x10-5).
OR
Discuss the theorys of neutralization indicators.
ii) Define a buffer by giving examples. How does a buffer resist change in pH?
3 Describe the various steps involved in gravimetric analysis.
ii) How do you prepare and standardize 0.1 N KMnO4 solution.
OR
Explain Mohr's method for determination of chlorides.
ii) What is oxidation reduction potential? How it is determined in a redox
system?
4 Write the principle and procedure involved in assay of calcium gluconate.
ii) Explain the principle, procedure in iodometric titrations.
OR
Explain theory and applications of non-aqueous titrations .
ii) Write a note on masking and demasking agents.
5 Define the terms:
Mole Empirical formula Molecular formula Theoretical yield
ii) Calculate the percentage composition of elements in K2Cr207 Cr=52,
0=16].
OR
How many moles are present in 53 gm of sodium carbonate and
60 grams of sodium hydroxide.
ii) Calculate the percentage composition of the elements in Na2S203
0=16].