FACULTY OF PHARMACY
B. Pharmacy 2/4 I-Semester (Non-CBCS) (Backlog) Examination, November 2018
Subject Pharmaceuticals Analysis I (Chemical Analysis)
Time 3 Hours Max. Marks: 70
Note: Answer all questions. All questions carry equal marks.
1 Define the following:
Accuracy Precisions standard deviation
What are significant figures? Write the rules for computation.
OR
Define the following:
Normality Molarity Molality Detection limit
Describe the procedure for calibration of pipettes and burettes
2 Explain the neutralization titration curve for the reaction between strong
acid and strong base. Comment on the indicators used.
Write the derivation of Handerson-Hesselbach equation used for the
determination of pH.
OR
Explain the following:
Law of mass action Ionic product of water
Write a brief note on hydrolysis of salts.
3 Discuss the various methods used in determination of end point in
precipitation titration.
Write a note on organic precipitants.
OR
Discuss the various types of redox titrations giving suitable examples. Write
reaction equations wherever necessary.
Write the factors affecting the precipitation titrations.
4 Discuss the principle and theory of complexotmetric titration. Write a note on
metal ion indicators.
Write the procedure for the preparation and standardization of 0.1 N
perchloric acid.
OR
Discuss the principle and procedure involved in argentometry.
Explain the principle of non-aqueous titrations.
5 Define the terms limiting reactant, theoretical yield and percentage yield.
Balance the following equations.
Ba Cl2 NaOH Ba(OH)2 NaCl
(B)H2SO4 FeCl3 Fe (SO4)3 HCl
(iii)Calculate the number of moles in each of the following:
7.9 gm of calcium 65.5 gm of carbon
OR
Write mass balance expressions for the system formed when a 0.010 M
NH3 solution is saturated with slightly soluble AgBr.
Find the percent composition of element calcium in calcium hydroxide.