FACULTY OF PHARMACY
Pharm. D YDC) I-Year (Instant) Examination, March 2018
Subject Medicinal Biochemistry
Time 3 Hours Max. Marks: 70
Note: Answer all questions from Part answer any five questions from Part-B.
PART A (10 x 2 20 Marks)
1 What is genetic code? Write characteristics of genetic code.
2 What is creatinine clearance? Write its diagnostic significance.
3 What are frame shift mutations and write its consequences?
4 Define Michaelis Menten constant and write its significance.
5 Give a short note on Gout.
6 Mention the effect of pH on enzymes activity.
7 Give a note on HDC and CDC ratio and its clinical significance.
8 Enumerate briefly functions of plasma membrane.
9 Explain briefly ketogenesis.
10 Write significance of glucose tolerance test.
PART B x 10 50 Marks)
11 Write components of electron transport chain and explain the mechanism of electron
transport.
12 Explain methods for determination of sodium, potassium and bicarbonates in body fluids.
13 Explain DNA repair mechanisms.
Describe HMP shunt pathway.
14 Describe in detail protein Biosynthesis.
15 Describe in detail about urine analysis.
16 Explain about water balance and its regulation in Body.
Discuss disorders of Acid-base balance.
17 Discuss in detail about Radio Immuno Assay.
18 Explain -oxidation of saturated fatty acids and write the total energy yield from complete
oxidation of one molecule of Palmitic Acid.