FACULTY OF PHARMACY
Pharm D I Year (Main Backlog) Examination, July 2018
Subject: Medicinal Biochemistry
Time: 3 Hours Max.Marks: 70
Note: Answer all questions from Part A. Any Five questions from Part B.
PART A (10x2 20 Marks)
1 Write the structural components of Eukaryotic ribosomes.
2 What is free energy and free energy change?
3 Write a note on glycogen storage diseases.
4 Write the characteristics of vesicular transport systems across cell membranes.
5 What is anion gap?
6 Explain briefly different states of nitrogen balance.
7 Explain the liver enzyme tests.
8 What is LDL-cholesterol and how it is measured from other components of lipid
profile.
9 Write briefly the metabolic derangements in diabetes mellitus.
10 What is hemolytic jaundice? How is it diagnosed?
PART B (5x10 50 Marks)
11 Explain in detail prokaryotic translation process.
12 Write the mechanism involved in regulation of body's acid-base balance and
maintenance of blood pH.
13 Explain the characteristics of reversible enzyme inhibition with their kinetics.
14 List out various renal function tests and explain the tests based on glomerular
function of kidneys.
15 Explain HMP pathway and its significance.
16 Write the procedure and interpretation of OGTT.
Explain the role of hormones in carbohydrate metabolism.
17 Explain dye tests for excretory function of liver.
Explain calcium and phosphate homeostasis in the body.
18 Explain oxidation of saturated fatty acids and write the total energy yield from
complete oxidation of one molecule of palmitic acid.