FACULTY OF PHARMACY
Pharm. D. YDC) IV Year (Instant) Examination, January 2018
Subject: Biostatistics and Research Methodology
Time 3 hours Max. Marks 70
Note: Answer all questions from Section-A and answer any
Five questions from Section-B.
Section A (10 x 2 20 Marks)
1 Define the primary Data. 2
2 What do you understand by Central Tendency? 2
3 Define the Coefficient of Variation. 2
4 How can you determine the size of the sample to be drawn? Explain. 2
5 State the principles of Experimental Design. 2
6 Explain the procedure of obtaining the Scatter Diagram. 2
7 Define the standard error. 2
8 Define Interval estimation 2
9 Define the Level of significance and Power of Test. 2
10 State the importance of SPSS in Pharmaceutical Applications. 2
Section B x 10 50 Marks)
11 The details of expenditures of two companies are given below. Draw suitable
graphical/diagrammatical representation and give your comments on the following
data. 10
Details of Expenditure Company A Company B
Rental charges 55,000 50,000
Electricity charges 32,000 30,000
Raw material charges 2,50,000 3,00,000
Transportation charges 75,000 50,000
Employees salaries 2,75,000 3,00,000
Miscellaneous charges 50,000 35,000
12 Compute the standard error of mean for the following data. 10
13 The duration for curing by using the drug produced by the four companies on
patients are given below. Test at level that the average duration for curing by
the drug is same. Consider the table values as (F22,3 3.24 F3,22 2.59). 10
Companies Days for cure
A 14 15 16 13 17 22 18
B 21 16 22 25 17
C 18 25 22 31 27 20
D 23 25 26 28 25 21 31 25
14 Derive the Regression line Y on X for the following data 10
X 25 32 42 56 65 72 49 57 45 75
Y 32 40 38 45 70 56 40 65 50 72
15 A drug is injected to 10 patients and the increase of blood pressure is noted as
Test at level is the drug
influencing in decreasing the B.P. 10
16 State the assumptions and limitations of the Mann-Whitney U-test. Also explain its
test procedure. Illustrate it with a suitable example. 10
17 State the characteristics of normal distribution. Give its importance. 10
18 State the features of statistical software SAS. Illustrate each with suitable
pharmaceutical applications. 10