FACULTY OF PHARMACY
Pharm D IV-Year (Main Backlog) Examination, July 2018
Subject: Biostatistics Research Methodology
Time: 3 Hours Max.Marks: 70
Note: Answer all questions from Part A. Any Five questions from Part B.
PART A (10x2 20 Marks)
1 Write the advantages of semilogarthimic plots.
2 Define data range and write its uses.
3 Define incidence and prevalence.
4 Explain null hypothesis and alternative hypothesis.
5 Define standard error of mean.
6 Define type-I error.
7 Define two tailed test.
8 Define and write the significance of confidence interval.
9 Explain parametric and non-parametric tests.
10 Write the merits and demerits of arithmetic mean.
PART B (50 Marks)
11 Explain in detail about observational and interventional studies in clinical study
design.
12 Explain in detail one-way ANOVA with example.
13 Calculate median, mode, standard deviation and variance from the following
frequency distribution of marks in biostatistics.
Marks 5 10 15 20 25 30 35 40 45 50
No. of students 20 43 75 76 72 45 39 9 8 6
14 Calculate the correlation coefficient between the height of the father and the son
from the given data.
Height of father (in inches) 65 66 67 68 67 69 70 64 65 63
Height of son (in inches) 68 65 68 70 67 68 72 66 68 62
Test the significance correlation coefficient and interpret the result



ttabulated at 2.31
at 3.36
..2
Library

15 The following figures shows disease count from a region over a span of 5
months. Represent the data by a pie-diagram.
Disease Disease count
HIV 13
Malaria 15
Diarrhoea 13
Tuberculosis 12
Influenza 17
In a study of diabetic patients, the following data were obtained. Draw a
histogram to represent the following data.
Age
(in yr)
No. of
persons
10 20 3
20 30 6
30 40 14
40 50 9
50 60 5
60 70 2
16 Explain in detail using suitable example.
Mann Whitney U Test
Chi-square test
17 Describe the role of computers in medication order entry, patient medication profile
and inventory control in hospital pharmacy.
18 Ten students were given intensive coaching in biostatistics. The scores obtained in
1st and 4th test are given below:
Sl.No. 1 2 3 4 5 6 7 8 9 10
Marks in 1st test 40 45 60 65 70 55 72 80 67 64
Marks in 4th test 55 52 54 53 64 59 68 71 73 52
Does the scores from test 1st to test 4th show an improvement?
[Ttabulated at 2.57