Exam Details
| Subject | principles of drug discovery | |
| Paper | ||
| Exam / Course | m. pharmacy (pharmacognosy) | |
| Department | ||
| Organization | G. Pulla Reddy College Of Pharmacy | |
| Position | ||
| Exam Date | August, 2018 | |
| City, State | telangana, hyderabad |
Question Paper
FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) II-Semester Main Examination,
August 2018
Subject Principles of Drug Discovery
Time 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1. Explain Target and lead with examples. Write about various methods of target
identification 15
2. Explain rational approach for drug design.
Explain in brief the role of proteomics in target identification.
3. What is QSAR? Give advantages and disadvantages of QSAR. Explain Hantzsch
analysis and Free Wilson analysis.
4. Write a note on CoMFA.
How computer aided drug design is useful in new drug discovery and
development.
5. Describe the methods of lead optimization.
What do you understand about De Novo drug design?
6. Write a note on prediction of protein structure.
Describe various lead seeking methods in drug design.
7. Write a note on
Drug likeness screening
pharmacophore based screening
8. Write a principle involved in design of pro-drug.
Explain the term molecular docking.
M. Pharmacy (Pharmacology) II-Semester Main Examination,
August 2018
Subject Principles of Drug Discovery
Time 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1. Explain Target and lead with examples. Write about various methods of target
identification 15
2. Explain rational approach for drug design.
Explain in brief the role of proteomics in target identification.
3. What is QSAR? Give advantages and disadvantages of QSAR. Explain Hantzsch
analysis and Free Wilson analysis.
4. Write a note on CoMFA.
How computer aided drug design is useful in new drug discovery and
development.
5. Describe the methods of lead optimization.
What do you understand about De Novo drug design?
6. Write a note on prediction of protein structure.
Describe various lead seeking methods in drug design.
7. Write a note on
Drug likeness screening
pharmacophore based screening
8. Write a principle involved in design of pro-drug.
Explain the term molecular docking.
Other Question Papers
Subjects
- advanced pharmacognosy-i
- advanced pharmacognosy-ii
- advanced pharmacology-i
- advanced pharmacology-ii
- cellular and molecular pharmacology
- clinical research and pharmacovigilance
- herbal cosmetics
- indian system of medicine
- industrial pharmacognostical technology
- medicinal plant biotechnology
- modern pharmaceutical analytical techniques
- pharmacological and toxicological screening methods - ii
- pharmacological toxicological screening methods – i
- phytochemistry
- principles of drug discovery