Exam Details
| Subject | principles of drug discovery | |
| Paper | ||
| Exam / Course | m. pharmacy (pharmacognosy) | |
| Department | ||
| Organization | G. Pulla Reddy College Of Pharmacy | |
| Position | ||
| Exam Date | February, 2019 | |
| City, State | telangana, hyderabad |
Question Paper
FACULTY OF PHARMACY
M. Pharmacy (Pharmacology) II-Semester (Suppl.) Examination,
February 2019
Subject: Principles of Drug Discovery
Time: 3 Hours Max. Marks 75
Note: Answer any five questions. All questions carry equal marks.
1. Write a note on economics of drug discovery. 7
Describe about role of zinc finger proteins in target identification and validation. 8
2. Write a note on combinatorial chemistry. 8
Explain in brief about reporter gene assay. 7
3. Write a note on drug likeness screening. 5
Explain in detail about rational drug design. 10
4. Write a note on rigid docking. 5
Describe in brief about QSAR. 10
5. Write the significance of Prodrug design. 5
Describe about the COMFA and COMSIA. 10
6. Explain in brief about role of bioinformatics in drug discovery. 6
Describe the computational prediction of structure. 9
7. Write a note on scintillation proximity assay. 6
Describe the concept of pharmacophore based screening. 9
8. Write a note on statistical methods in QSAR. 8
Describe in brief about rational of Prodrug design. 7
M. Pharmacy (Pharmacology) II-Semester (Suppl.) Examination,
February 2019
Subject: Principles of Drug Discovery
Time: 3 Hours Max. Marks 75
Note: Answer any five questions. All questions carry equal marks.
1. Write a note on economics of drug discovery. 7
Describe about role of zinc finger proteins in target identification and validation. 8
2. Write a note on combinatorial chemistry. 8
Explain in brief about reporter gene assay. 7
3. Write a note on drug likeness screening. 5
Explain in detail about rational drug design. 10
4. Write a note on rigid docking. 5
Describe in brief about QSAR. 10
5. Write the significance of Prodrug design. 5
Describe about the COMFA and COMSIA. 10
6. Explain in brief about role of bioinformatics in drug discovery. 6
Describe the computational prediction of structure. 9
7. Write a note on scintillation proximity assay. 6
Describe the concept of pharmacophore based screening. 9
8. Write a note on statistical methods in QSAR. 8
Describe in brief about rational of Prodrug design. 7
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