FACULTY OF PHARMACY
M. Pharmacy (Pharm. Analysis) II-Semester (Main) Examination,
August 2018
Subject: Modern Bio Analytical Techniques
Time: 3 Hours Max. Marks: 75
Note: Answer any five questions. All questions carry equal marks.
1 Write notes on bio analytical method validation as per FDA Guidelines?
2 Explain the factors effecting for enhancement of bioavailability of drugs?
3 Describe the Cytochrome P450-based drug interactions
4 Write brief notes on
Various types of cell culture
LC-MS in bioactivity screening and proteomics
5 Describe the principles and applications of cell viability assays of MTT assays?(15)
6 Write the alternate methods for dissolution testing?
7 Define and explain bioavalability, bioequivalence and biosimilar.
Write about various design to conduct bioavailability studies.
8 Discuss about the bioanalytical methods such as protein precipitation.
Describe the various solubility techniques.