FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
APRIL 2016
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER I
PATHO/APRIL/16/32/I
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Pathophysiology of osteoporosis.
Pathphysiology of disseminated intravascular coagulation.
5+5
2. What is sarcoidosis? Give its etiology and pathogenesis.
Morphological changes in various organs in sarcoidosis.
5+5
3. Mechanism of hematogenous spread of tumors.
Telomerase activity in health and disease.
5+5
4. Antinuclear antibodies immuno-florescence pattern and
interpretations.
Role of electron microscopy in diagnostic pathology.
5+5
5. Graft versus host disease.
Mechanism of iron absorption.
5+5
6. Prenatal diagnosis methods utility.
Methods of evaluation of HbA1C, its role in diagnosis and
monitoring of diabetes mellitus.
5+5
7. Pathogenesis of autoimmune thyroiditis.
Role of trace elements in health and disease.
5+5
8. Microarray technique its applications.
Role of IHC in differential diagnosis of lymphoproliferative
lesions.
5+5
9. What is an atheroma?
Various risk factors and pathogenesis of atherosclerosis.
Various acute coronary events and their consequences.

10. Mechanism of apoptosis.
Angioneurotic oedema.
5+5