FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2018

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
PATHOLOGY
PAPER-II
PATH/J/18/32/II
Time: 3 hours
Max. Marks:100
Important Instructions:
Attempt all questions in order.
Each question carries 10 marks.
Read the question carefully and answer to the point neatly and legibly.
Do not leave any blank pages between two answers.
Indicate the question number correctly for the answer in the margin space
Answer all the parts of a single question together.
Start the answer to a question on a fresh page or leave adequate space between two answers.
Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:


1. Paris system of reporting in Urinary cytology.
Genomic imprinting
5+5
2. Microalbuminuria and its detection.
Significance of HbA1c estimation.
5+5
3. Immunofluorescence and its application in glomerular
diseases.
Principle of Fluorescence In-Situ Hybridization (FISH) its
application in solid tumours.
5+5
4. Serum tumour markers and their significance.
Role of enzyme histochemistry in muscle biopsy.
5+5
5. Molecular subtyping of embryonal brain tumours.
Markers in lung carcinoma with respect to newer
classification and treatment.
5+5
6. Processing of fluids for cytological examination.
Morphological and immunochemical markers in the
differential diagnosis of mesothelioma and adenocarcinoma
in fluids.
5+5
7. Limitation of FNAC of thyroid nodule.
Utility of Endobronchial Ultrasound(EBUS) guided FNAC
5+5
8. Diagnostic approach to atypical glandular cells in cervical
smear.
Microsatellite instability in Cervical Cancer.
5+5
9. Current understanding in the pathology of hydatidiform
moles.
Molecular classification of breast cancer.
5+5
10. Role of molecular markers to categorize soft tissue
sarcomas.
Role of immunohistochemistry in problematic prostate biopsy.
5+5