FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
JUNE 2017
POSSESSION USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE
EXAMINATION HALL.
PATHOLOGY
PAPER II
PATH/J/17/32/II
Time 3 hours
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Use of IDH, ATRX and Ip19q in classification of gliomas in recent
WHO Classification.
Techniques of Cell block preparation for fine needle and exfoliative
cytology samples.
5+5
2. Principle and applications of confocal microscopy.
Pathophysiology of autophagy and its role in tumour development
and storage disorders.
5+5
3. Role of histopathologists in stratified medicine treatment of cancers.
Nesidioblastosis
6+4
4. Anti-NMDA encephalitis.
Merits and demerits of various serum/tissue fluids based tuberculosis
test.
5+5
5. Endoscopic ultrasound guided FNA and approach to cystic pancreatic
lesion reporting.
Intra-operative squash smear cytology reporting of CNS lesion
advantage and limitations.
5+5
6. Next Generation Sequencing Its role and advantages.
siRNA and its role in disease and treatment.
5+5
7. Compare and contrast between "ThinPrep" Vs 'SurePath'
preparations of liquid based cytology.
BRAF V600 E mutation and its role in CNS and other lesions.
5+5
8. Components and principles of Papanicolaou stain.
HPV-Hybrid capture technique principles and assessment.
5+5
9. Cytofixatives and its type: Use and advantages.
Role of cytogenetics in diagnosis and management of soft tissue
tumours.
5+5
10. miRNA in cancer.
Pathology of acute lung injury.
5+5