FINAL EXAM NATIONAL BOARD OF EXAMINATIONS
DECEMBER 2017
BIOCHEMISTRY
PAPER I

POSSESSION/USE OF CELL PHONES OR ANY SUCH ELECTRONIC GADGETS IS NOT PERMITTED INSIDE THE EXAMINATION HALL.
Time 3 hours BIO/D/17/03/I
Max. Marks 100
Important instructions:
• Attempt all questions in order.
• Each question carries 10 marks.
• Read the question carefully and answer to the point neatly and legibly.
• Do not leave any blank pages between two answers.
• Indicate the question number correctly for the answer in the margin space.
• Answer all the parts of a single question together.
• Start the answer to a question on a fresh page or leave adequate space between two
answers.
• Draw table/diagrams/flowcharts wherever appropriate.
Write short notes on:
1. Internal Quality Control
Proficiency testing
5+5
2. Important biochemical cardiac markers useful for early
and late diagnosis of acute myocardial infarction.
5+5
3. Biochemical risk factors for coronary artery diseases
(CAD). Add a note on Lp(a).
7+3
4. Examination of amniotic fluid and its importance in
prenatal diagnosis.
6+4
5. Biochemical basis and clinical features of Gout. Add a
note on investigations and different treatment modalities.

6. Metabolic acidosis
Anion gap
5+5
7. Enumerate unsaturated fatty acids and their
physiological nutritional significance.
4+6
8. Glycated hemoglobin, different forms, interpretation and
false positive /negative results.

9. Genetic diagnosis of HIV infection.
Biochemical parameters estimated in Cerebrospinal
Fluid for diagnosis of different types of
meningitis.
5+5
10. Adenosine deaminase deficiency
Bence Jones protein
5+5