DISTANCE EDUCATION
M.Sc. (Zoology) DEGREE EXAMINATION, DECEMBER 2017.
CELL AND MOLECULAR BIOLOGY
Time Three hours Maximum 100 marks
PART A — x 8 40 marks)
Answer any FIVE questions.
1. Elucidate the different models of structure of plasma
membrane.
2. What is electron transport chain? What are the sources of
substrates of electron transport chain?
3. Explain the function of different DNA polymerases in
eukaryotes.
4. Distinguish between leading strand synthesis and
lagging strand synthesis.
5. Draw the schematic representation of the fork model of
DNA replication.
6. Give a brief account on initiation of transcription by RNA
polymerase I and II.
7. Define motif. What are zinc finger motif and explain its
role?
8. Comment on hormonal regulation of gene expression.
PART B — x 15 60 marks)
Answer any FOUR questions.
9. Draw the ultrastructure of mitochondria. Briefly describe
its functions.
10. What is kinetochore? Explain the molecular mechanism
of microtubule attachment with kinetochore.
Sub. Code
12
DE-3054
2
SER
11. Write an essay on the enzymology of DNA replication.
12. Write notes on
Central dogma
Polyadenylation
Splicing
Exon and introns
RNA polymerase.
13. What is genetic code? Give a detailed account on origin
and evolution of genetic code.
14. Write an essay on post-translational modifications in
prokaryotes.
15. Comment on the following
Hormonal regulation of gene expression
Lac operon
DNA binding motifs in prokaryotes.