DISTANCE EDUCATION
M.Sc., (Zoology) DEGREE EXAMINATION, MAY 2018.
CELL AND MOLECULAR BIOLOGY
Time Three hours Maximum 100 marks
PART A — x 8 40 marks)
Answer any FIVE questions.
1. Draw and describe the structure of prokaryotic cell.
2. Distinguish between euchromatin and heterochromatin.
3. What is replication? Comments on the experimental
evidence on bidirectional replication.
4. Briefly describe the elongation and termination phases of
replication in eukaryotes.
5. Write notes on
Transcription
Promoters
Initiation
Elongation
6. Explain various types of RNA and their functions in the
cell.
7. Define Wobble hypothesis. Give the reasons of wobble
pairing.
8. Give a brief account on mechanism of regulation of
eukaryotic promoters.
Sub. Code
12
DE-4166
2
sp4
PART B — × 15 60 marks)
Answer any FOUR questions.
9. What is endoplasmic reticulum? Draw the ultrastructure
of endoplasmic reticulum and its functions.
10. Give a detailed account on molecular mechanism of
initiation of replication in S-phase.
11. List out the enzymes and proteins required for DNA
synthesis and explain their mode of action.
12. Write an essay on the differences between the prokaryotic
and eukaryotic transcription.
13. Illustrate the structure and functions of the reverse
transcriptase enzymes.
14. Describe the different steps involved in elongation of
protein synthesis in prokaryotes and eukaryotes.
15. Write notes on the following:
Transcription factor
DNA binding motifs in prokaryotes
Steroid receptors