M.Sc. (Semester III) (CBCS) Examination Oct/Nov-2017
Biotechnology
ADVANCED PHARMACEUTICALS
Day Date: Saturday, 25-11-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
Instructions: Section I is compulsory.
Answer any four questions from Section II.
Section I
Q.1 Multiple Choice Questions: 07
Two solution are said to be isotonic if they exert same.
Viscosity Surface tension
Osmotic Pressure None of the above
Buffer index can be defined as the ratio of the increment of strong base/
acid to the
Change in pH Change in Viscosity
Change in osmotic pressure None of the above
Toxicity is measured on the basis of properties.
Pharmacological Pharmaceutical
Rheological Colligative
Dissolution is affected by
Surface area Viscosity
Temperature All of the above
Electro dialysis is a method for the purpose of
Purification Identification
Preparation Stabilization
The temperature at which the solubility of the surfactant is equal to CMC
is
Boiling point Melting point
Kraft point None of the above
Finely divide powder have wettability.
Average Good
Poor Moderate
Define the following terms: 07
Dissolution of drug
USP
Carriers
Co-solvent
Surfactant
Antibacterial activity
Emulsion
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Section II
Q.2 Explain in details about hydrotrophy in pharmaceuticals. 14
Q.3 Describe the methods of polymerization and its characterization. 14
Q.4 Discuss about the stability studies of the drug. 14
Q.5 Answer any two of the following: 14
Characterization of granules and compacts
Factors affection dissolution rate.
Solid dispersion.
Q.6 Write short notes on any TWO of the following. 14
Biodegradable polymer
Cyclodextrin
Kinetics of the drug