M.Sc. (Semester (CBCS) Examination Oct/Nov-2017
Bioinformatics
BASIC BIOINFORMATICS
Day Date: Thursday, 16-11-2017 Max. Marks: 70
Time: 10.30 AM to 01.00 PM
Instructions: Section-1, Question 1 is compulsory.
Attempt any four questions from Section-II.
Figures to the right indicate full marks.
Answer to the Section-I and Section-II are to be written in same answer
Booklet only.
Section I
Q.1 Rewrite the sentence after choosing the correct answer from the
given alternatives:
07
program compares a protein query against the all six
reading frames of a nucleotide sequences database.
Blastp tblastx
tblastn all of these
OMIM stand for
Ontology Mechanism In Man
Online Machine Interface mapping
Online Machine inheritance in Man
Online Mendelian Inheritance in Man
GUI stands for
Graphical User Interface Genic User Interphase
Genome User Interface None of these
SVM stands for
Species Vector Machine Support Vector Machine
System Vector Machine None of these
The protein secondary database is
NCBI GenBank
NRL-3D Pfam
FTP stands for
Form Transferring Page File Transfer Practice
File Transfer Protocol Field Transfer Protocol
NBRF it stands for
National Biomedical Research Foundation
Nation Biological Research Fund
National Biomedical Research Fund
Nation Biological Research Foundation
Page 2 of 2
SLR-MC-62
Definitions. 07
Sequence similarity
BLASTn
Phylip
Enterz
PIR
Neural Network
SVM
Section II
Answer any four of the following.
Q2 Explain Neural Networks and add a note o Support Vector Machine. 14
Q3 Give the detailed account on NCBI and explain the nucleotide sequence
database in details.
14
Q4 What is String Matching Algorithm and add a note on BLAST and FASTA
sequence comparison.
14
Q5 Answer any two of the following. 14
Explain the Gene array analysis and its applications.
Give an account on Entrez and SRS tools.
Explain ClustalW and TreeView in details.
Q6 Write short note any two of the following. 14
GenBank File Format
PIR
Applications of Bioinformatics.