M.Sc. (Semester III) (CBCS) Examination Oct/Nov-2017
Genetics
IMMUNOLOGY IMMUNOTECHNOLOGY
Day Date: Thursday, 16-11-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
Instructions: Section-I compulsory.
Attempt any four from Section-II.
Section I
Q.1 Choose the correct alternative and rewrite the sentences. 07
1g) MHC genes in human are present on chromosome.
7 14
6 12
2 Phycoerythrin is used in test
Radioimmunoassay Immune-fluorescence
ELISA Complement fixation
3 Active immunization is done by using
Vaccines Hyper immune sera
Immune sera Convelescent
4 antibody in called as secretary antibody.
IgG IgM
IgA IgE
is primary lymphoid organ.
Spleen Lymphnode
Peyer's patch Thymus
6 The incomplete antigen is called as
Epitope Adjuvant
Hapten Antibody
The first step in the classical complement activation pathway is

Binding of C1 to antigen-antibody
Binding of C3b to an activator
Binding of C2 to an activator
Binding of antigen of C1
Define the following terms. 07
Define acute and hyper acute graft rejection
Properties of cytokines
Enlist factors affecting innate immunity
ELISA
Difference atopy
Give any two organ non-specific autoimmune diseases
Function of B cells
Page 2 of 2
SLR-MK-431
Section II
Answer any four of the following
Q.2 Give structural, morphological, cultural, life cycle and pathogen city characters,
Lab diagnosis, Prophylaxis of HIV virus.
14
Q.3 Explain mechanism of processing and presentation of endogenous antigen. 14
Q.4 B cell activation, proliferation and differentiation. 14
Q.5 Answer any two from the following. 14
Explain structure of MHC class II molecule.
Explain factors affecting antigen city and types of antigens.
Mechanism of allograft recognition.
Q.6 Answer any two from the following. 14
New trend vaccines
Classical complement pathway
Write an essay on principle of antigen and antibody interaction