M.Sc. (Semester III) (CBCS) Examination Nov/Dec-2018
GENETICS
IMMUNOLOGY AND IMMUNOTECHNOLOGY
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Figures to the right indicate full marks.
Draw neat labeled diagrams.
Q.1 Rewrite the sentences by choosing correct answer from given alternatives: 14
Spread of viral infection is avoided by as member of innate immunity.
interleukin interferon
chemokine tumor necrosis factor
In the cell-mediated immunity complex plays important role in
antigen presentation.
class I MHC class II MHC
class III MHC class IV MHC
Resistance against Tuberculosis and Leprosy is carried through
immune response.
cell mediated humoral
primary secondary
IgE dependent hypersensitivity is type Hypersensitivity.
I II
III IV
Salk polio vaccine is example of vaccine.
killed viral killed bacterial
live viral live attenuated bacterial
Macrophage cells present in liver are called as
Langerhan Kupffer
Microglial Alveolar
Blood born antigens are recognized in
spleen bone marrow
lymph node thymus
Antibody mediated complement activation is called pathway.
Lectin Alternative
Classical Properdine
Factors B and D are required for activation of Complement's
pathway.
classical alternative
lectin none of these
10) Protein antigens are antigenic than polysaccharide antigens.
less medium
more none of these
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SLR-VK-316
11) antibody can pass the placenta.
IgA IgD
IgG IgM
12) Serum IgM molecules usually contain
10 light chains 10 heavy chains
Joining chain All of these
13) Diagnosis of Syphilis by using test is an example of slide
flocculation test.
Mancini Oudin
VDRL Kahn
14) End products of enzyme-substrate reaction are analyzed in test.
Radioimmunoassay Immunoflurescence
ELISA Precipitation
Q.2 Answer the following (Any
1. Differentiate Cell mediated and Humoral Immunity.
2. Give the significance of cytokines.
3. Enlist types of Antigens.
4. Write on mechanism of Graft rejection.
5. Discuss immunofluorescence.
08
Write notes on (Any
1. Inflammation
2. Properties of IgE
3. T suppressor cells
06
Q.3 Answer the following (Any
1. Discuss anatomical barriers of innate immunity.
2. Write on structure and functions of thymus.
3. What is Acquired Immunity? Explain types of it with examples.
08
Answer the following (Any
1. Write on MHC complex.
2. What is Complement system? Give its functions.
3. What are Antigens? Elaborate on factors affecting antigenicity.
06
Q.4 Answer the following (Any
1. Describe basic structure of immunoglobulin with well labeled diagram.
2. Write on Genetics of antibody diversity.
3. Explain Type I hypersensitivity with examples.
10
Answer the following (Any
1. What is autoimmunity? Give its types.
2. Write on the role of immune system in cancer.
04
Q.5 Answer the following (Any Two) 14
Describe in detail the mechanism and application of immunoprecipitation.
Write on complement fixation test.
Explain the mechanism and applications of ELISA.