M.Sc.(Microbiology) (Semester IV) (CBCS) Examination, 2017
HEALTH CARE AND DIAGNOSTIC MOCROBIOLOGY
WateriI
Day Date: Wednesday, 19-04-2017 Max. Marks: 70
Time: 02.30 PM to 05.00 PM
N.B. Part Question 1 is compulsory.
Attempt any FOUR Question from part II.
Figures to right indicate full marks.
Answer to Part-I and Part -II are to be written in same
answer booklet only.
Part-I
Q.1 Rewrite the sentences after choosing correct answer from
the given alternatives.
14
Toxoids are produced by
Endotoxins Exotoxins
Lipopolysaccharide All of these
2 Which of the following antibiotic is NOT used as food
preservative?
Pimaricin Tycorin
Nisin Beta-lactam antibiotic
3 Which of the following synthesis/function is affecting by
Streptomycin and tetracycline antibiotic
Protein synthesis DNA function
Cell wall synthesis Cell membrane function
4 Cancers can be diagnosed
PCR IHC
Tumor market All of these
5 Which of the following antibiotic/ drug may show plasmid
mediated resistance
Nalidixic acid Rifamycin
Ampicillin Methicillin
6 The ability of organisms to invade tissues of body are

Toxigenesis Colonization
Invasiveness None of these
7 Extracellular bacterial proteins are responsible for
Invasion Colonization
Adhesion None of these
Page 2 of 3
8 is the inhibitors of protein synthesis
Polymixin Erythromycin
Acridines Vancomycin
9 Beta lactams ring is present in antibiotic.
Gentamicin Chloramphenicol
Penicillin Tetracycline
1 In ELISA test mostly is used.
Horse raddish perodixase Alkaline phosphatase
Lipase Urease
1 Streptococci enzyme as invasion
substance that degrade hyluronic acid of connective tissue.
Coligenase Kinases Leucocidin hyluronidase
1 Entry of pathogen in the body is called
Colonization Disease Toxogenesis infection
1 ability to cause disease is called
Virulence Invasiveness
Toxigenesis Pathogenicity
1 toxin is plasmid encoded.
Tetanus Diphtheria Endotoxin Cholera
Attempt any question from part II
Q.2 Write in brief on "Adhesion, invasion, and colonization of host tissues
by bacterial pathogens"
14
Q.3 Write in short on "Mechanism of action of Trimethoprim and
sulphonamide drugs"
14
Q.4 Write in details on "Ecodotoxins of gram negative bacteria". 14
Q5 Write in short on any Two of the following 14
Antifungal and antiviral drugs.
Antibiotic assay
Antibiotic sensitivity testing
0
Q.6 Write short notes on any FOUR of the following 14
Roll of microbiology laboratory in pharmaceutical industry.
Use of antigen antibody reaction for diagnosis of diseases
ELISA test used for diagnosis of diseases.
Florescence in situ hybridization (FISH).
Rapid methods of identification of microorganisms.
What is Toxigenicity testing of a drug and LD50 titre?