M.Sc. (Semester (CBCS) Examination Mar/Apr-2018
Biotechnology
BIOSTATISTICS AND BIOINFORMATICS
Time: 2½ Hours
Max. Marks: 70
Instructions: Section is compulsory. Attempt any-4 question from Sections II All questions carry equal marks. Use of non-data storage calculator is allowed.
Section I
Q.1

Rewrite the sentence after choosing the correct answer from the given alternatives:
07
A subset of the population selected to help make inferences on a population is called
a population
inferential statistics
a census
a sample
A measure of the strength of the linear relationship that exists between two variables is called
Slope
Intercept
Correlation coefficient
Regression equation
If the critical region is located equally in both sides of the sampling distribution of test-statistic, the test is called
One tailed
Left tailed
Right tailed
Two tailed
The mean deviation about mean of data is




In Ramchandran plot during validation of protein structure torsion angles are considered.
and
and
and
and
Solution to the Newton's equation of motion for the nuclei is known as
quantum dynamics
molecular dynamics
conformational search
molecular trajectories
The study of complete genome of organism is known as
Proteomics
Genomics
Metabolamics
Transcriptomics
B)Define the following:
07
Variable
Inclusive class
P-value
SRS
Database
Global alignment
Docking
Page 2 of 2
SLR-UE-87
Section II
Answer Any Four of the following:
Q.2
Write an essay on Homology Modeling.
14
Q.3
Calculate the arithmetic mean, median and mode from the following data:-
Age at last birthday
15-19
20-24
25-29
30-34
35-39
40-44
Number
4
20
38
24
10
9
14
Q.4
Answer any Two of the following:-
14
a)Discuss about the pairwise sequence alignment.
b)Calculate the standard deviation from the following data 10, 13, 17, 22, 27, 30, 31, 32
c)Describe in detail GenBank.
Q.5
Write short note on any Two of the following:-
14
a)Write a note on Analysis of Variance (ANOVA)
b)Molecular dynamic simulation
c)Represent the following data by histogram
No. of tillers per plant
0-6
6-12
12-18
18-24
24-30
30-36
Number of Plants
4
8
15
20
12
6
Q.6
Write Short Notes on any two of the following:
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a)Conformational search and docking
b)Discuss in detail about random sampling method
c)Distance based and character based approach of phylogenetic analysis