M.Sc. (Semester III) Examination Nov/Dec-2018
INDUSTRIAL CHEMISTRY
ADVANCED TOPICS IN INDUSTRIAL CHEMISTRY II
Time: 2½ Hours Max. Marks: 70
Instructions: All questions are compulsory.
Q.1 Multiple choice questions 14
Which gas has the highest calorific value among given option?
Oxygen Helium
Hydrogen Nitrogen
What accounts for the presence of water in the exhaust leaving as vapor?
Gross calorific value Flash point value
Ignition temperature value Net calorific value
Which formula is used to determine higher calorific value of fuel?
Rayleigh's formula Lamme's equation
Dulongs's formula Cauchy's formula
Greenhouse gas which can be emitted from storage of nitrogen based
fertilizers is
Nitrous oxide Nitric oxide
Oxygen Hydroxide
Which of the following is not a nitrogenous fertilizer?
Urea Ammonium sulphate
Super phosphate Ammonium nitrate
Ammonium nitrate (is mixed with limestone) is not used as fertilizer as such
because
acidic in nature
hygroscopic and explosive in nature
liquid at room temperature
nitrogen content is very less
Which of the following statements is not true regarding the binding site of a
receptor?
The binding site is normally a hollow or cleft in the surface of a receptor
The binding site is normally hydrophobic in nature
Chemical messengers fit into binding sites and bind to functional groups
within the binding site
The binding site contains amino acids which are important to the binding
process and a catalytic mechanism
Which of the following statements best describes pharmacodynamics?
The study of how drugs reach their target in the body and how the levels
of a drug in the blood are affected by absorption, distribution, metabolism
and excretion
The study of how drugs can be designed using molecular modeling
based on a drug's pharamacophore
The study of how a drug interacts with its target binding site at the
molecular level
The study of which functional groups are important in binding a drug to its
target binding site and the identification of a pharamacophore
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Which of the following statements is not true about receptors?
Most receptors are proteins situated in the cell membrane.
Receptors contain a hollow or cleft on their surface which is known as a
binding site
Receptors bind chemical messengers such as neurotransmitters or
hormones
Receptors catalyse reactions on chemical messengers
10) Which one of the following is NOT true?
Modified release formulations are most useful for drugs with a long halflife
Modified release formulations can often reduce side-effects
Modified release formulations can improve patient compliance
Modified release formulation can be used for local drug delivery
11) Which one of the following is not a route of administration?
Intravenous Oral
Topical Dissolution
12) In the formulation of suspensions, generally which types of drugs are
selected?
Hydrophilic Hydrophobic
Both None
13) One of the principles of green chemistry says that to produce goods.
Harmful Commercial
Safer Most used
14) Green chemistry improves of chemical manufacturers.
Competitiveness Easiness of production
Services Chemicals
Q.2 Answer the following (any four) 08
Define calorific value
Give the structure of chloroquine
Give the classification of Solid dosage forms
Define atom economy
Give the examples of phosphate fertilizers
Write notes on (any two) 06
Analysis of Liquid fuel
Potassium by sodium tetraphenyl borate method
DNA as receptor
Q.3 Answer the following (any two) 08
Describe the importance of cloud point and pour point determination in
lubricant.
Explain significance of ED50.
Give the classification of Route wise dosage forms
Answer the following (any one) 06
Give an account on Solid dosage forms.
Explain with suitable example Schnoiger's Oxygen flask method in
analysis of drugs.
Q.4 Answer the following (any two) 10
Give the synthesis and application of drug chloroquine.
Describe in details the Orsat apparatus and its use in exhaust gas
analysis.
Give the principle of Green Chemistry.
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Answer the following (any one) 04
Explain in detail the proximate analysis of coal.
Discuss in brief Kjeldahl nitrogen method.
Q.5 Answer the following (any two) 14
Explain in detail assay of any one analgesic drug.
Give the synthesis and application of drug
Salbutamol
ii) Ibuprofen
Discuss in detail the concept of prodrug with examples.