B.Sc. II Entrepreneurship (Semester IV) (New CBCS)
Examination, 2018
Microbial biotechnology (Paper VII)
Molecular Biology
Day and Date Wednesday, 12-12-2018 Total Marks 70
Time 10.30 a.m. to 1.00 p.m.
1. Rewrite the correct alternative from the following questions. 14
Topoisomerase is involved in
Producing RNA primer Joining DNA segments
Producing nick in DNA Separation of DNA strands
DNA strand is synthesized in the direction


The one which is capable of self replication is
DNA RNA
Enzyme Protein
DNA polymerase is
DNA dependent DNA polymerase
RNA dependent RNA polymerase
RNA dependent DNA polymerase
DNA dependent RNA polymerase
is not associated with DNA polymerase I.
to exonuclease activity to endonuclease activity
to exonuclease activity to polymerase activity
Seat
No. Set P
P.T.O.
Promoter is a
A specific sequence of DNA to which a catabolic repressor binds
A specific sequence of DNA to which RNA polymerase binds
A specific DNA sequence to which a restriction endonuclease binds
None of the above
RNA polymerase in prokaryotes has a removable
Alpha subunit Beta subunit
Both and Sigma subunit
In human, the inherited autosomal recessive diseases Xeroderma
pigmentosum is the result of a defect in the
SOS repair Mismatch repair
Repair in alkylated DNA Repair of UV damaged DNA
In bacterial promoters, describes the 'Pribnow box.
The untranslated region The -35 box
The-10 box The termination sequence
10) directly reverses DNA damage.
AP endonuclease UVr-ABC
MutS and MutL Methyltransferase
11) Rifampicin is a specific inhibitor of
Bacterial RNA polymerase RNA polymerase III
RNA polymerase I RNA polymerase II
12) During DNA replication in E.coli, RNA primers are synthesized by
dna B dna G dna C dna A
13) The 20 different amino acids found in proteins are normally coded by
59 condons 64 codons
61 codons 63 codons
14) is not property of genetic code.
Non-ambiguous Non-overlapping
Degeneracy Ambiguous
SLR-SK 31 *SLRSK31*
Set P
2. Answer any seven of the following 14
RNA Polymerases in Eukaryotes.
Enhancers.
Termination of replication in eukaryotes.
Topoisomerase.
The Central Dogma.
Draw structure of DNA.
Explain Operon concept.
DNA polymerase in prokaryotes.
What are ribosomes
3. Answer any two of the following 10
Discuss in brief salient features of DNA.
Explain genetic code and its properties.
Briefly explain Direct repair system
Write an account on Enzyme involved in eukaryotic Replication. 4
4. Answer any two of the following 14
Discuss in brief Translation.
Write an assay Rolling Circle Model of DNA.
Replication in Prokaryotes.
5. Answer any two of the following 14
Explain Lac Operon.
Describe Post transcriptional modification.
Discuss in brief Translation in Prokaryotic Cell.