B.Sc. III Biotechnology (Semester (Old CGPA) Examination, 2018
bioinformatics and nanotechnology
Day and Date Thursday, 22-11-2018 Total Marks 70
Time 2.30 p.m. to 5.00 p.m.
Instructions All questions carry equal marks.
Figures to right indicate full marks.
Draw neat and labeled diagrams wherever necessary.
1. Rewrite the following sentences by using correct alternative. 14
For antibacterial activity nanoparticles are widely used.
Manganese Cobalt
Silver Molybdenum
The suitably modified polymeric nanoparticles in the form of loaded with drugs are able to pass the blood brain barrier.
Liposomes Fullerenes
Quantum dots Nanotubes
The term nano was first coined
Alexander fleming John Tyndall
Richard Fynmann Rutherford
High energy ball milling is a method of nanoparticle synthesis.
Physical Chemical
Bilological Natural
The mechanism involves gathering of entities without any external influence.
Polymerization Degradation
Isomerization Self assembly
Nanoparticles are used in therapy by placing a nanodot inside the body and illuminating it from outside.
Imaging Chemo
Photodynamic Natural
The ability of one molecule to attract and bind to another is often referred to as
Crystallization Molecular recognition
Agglumeration Coagulation
Tree view is used for constructing
Multiple alignment Dendogram tree
Local alignment Global alignment
Sanger Centre, HGMP-RC, EBI is hosted by
Hinxton Hall MIPS
UCL NCBI
10) The PubMed provides information of database.
Nucleotide Protein Genome Literature
11) The protein sequence database is
GenBank EMBL
DDBJ SWISS-prot
12) blast is used for alignment.
Global Local
Multiple Global and local
13) alignment is widely used for prediction of phylogenetic relationship.
Global-pairwise Local-pairwise
Global-multiple Local-multiple
14) The structural database of nucleic acids
PDB NRL-3D
GenBank NDB
2. Answer any seven of the following 14
Which techniques are used for synthesis of nanomaterials by physical methods
Enlist different types of lithography.
What is TrEMBL
What is quantum mechanics
What is consensus sequence Give example.
What are BLOSUM matrices
What is the difference between top down and bottom up approach of nanomaterial synthesis
What is SCOP database
What are different nano size materials in human body
3. Answer any two of the following 10
Describe the primary protein sequence databases.
Add a note on quantum idea and quantum mechanics.
Add a note on polymerization of nanomaterials.
Describe various applications of Bioinformatics. 4
4. Answer any two of the following 14
Describe biological methods of nanomaterial synthesis.
Describe tools for measurement of nanostructures.
Describe various properties of nanostructures.
5. Answer any two of the following 14
What is structural database Explain any three Protein Structural Databases.
What is biological database Explain nucleic acid sequence database.
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