FEBRUARY 2018 Sub. Code: 2112
B.Sc. NUCLEAR MEDICINE TECHNOLOGY
SECOND YEAR
PAPER II RADIOCHEMISTRY AND RADIO PHARMACY
Q.P. Code: 802112
Time: Three Hours Maximum: 100 Marks
Answer all questions
I. Elaborate on: x 10 30)
1. Explain the factors influencing the design of new radiopharmaceuticals.
2. Explain the principles of Cyclotron Produced Radionuclides with examples.
3. Explain Iodination of I131- mIBG.
II. Write notes on: x 5 40)
1. Discuss the washing and autoclaving methods for glass wares.
2. Explain Molecular Biology and Immunology.
3. Explain the Target and its processing of Radionuclides.
4. Define Physical and Biological Half-Life.
5. Explain Proteins and Amino acids.
6. Explain Transient Equilibrium.
7. Mention the methods of Sterilization.
8. Lyophilization of cold kits.
III. Short answers on: (10 x 3 30)
1. Define Acids and Bases.
2. Membrane Filtration.
3. Explain Mobile phase.
4. Dative Bond and Hydrogen Bond.
5. Ion Exchange reaction.
6. Explain references of 50% 10%.
7. Protein Binding.
8. Shelf Life.
9. Head damaged RBC's.
10. Tracer Kinetics.