FEBRUARY 2017 Sub.Code :2112
B.Sc. NUCLEAR MEDICINE TECHNOLOGY
SECOND YEAR
PAPER II RADIOCHEMISTRY AND RADIO PHARMACY
Q.P. Code: 802112
Time: Three Hours Maximum: 100 Marks
Answer All questions
I. Elaborate on: x 10 30)
1. Explain the mechanism and localization of radiopharmaceuticals.
2. Explain the various equilibrium's in generator produced radionuclides.
3. Explain cell labeling with Tc99m.
II. Write Notes on: x 5 40)
1. Radio-iodination methods.
2. Radionuclide generators for Tc99m.
3. pH importance in radiopharmaceuticals.
4. LAL test.
5. Chromatography.
6. Moly breakthrough test.
7. Reactor produced radionuclides.
8. Radionuclide separation techniques.
III. Short Answers on: (10 x 3 30)
1. Tc99m DTPA structure.
2. Antioxidants.
3. Various bone imaging tracers.
4. Coordination bone.
5. Chelating agents.
6. Radiolysis.
7. I131 mIBG.
8. Centrifuge.
9. Neutron capture.
10. Tracers used for infection imaging.