1. Ninhydrin test is given by

Carbohydrates

Proteins

Alkanes

Alkenes

2. Which immunoglobulin is the principal one found in secretions such as milk?

IgG

IgA

Ig0

IgM

3. Non-proliferative phase of cell cycle is

Gl->GO

S

Gl->G2

M

4. LeucosoLenia is an example of which class of the phylum Porifera?

Hevactinellidae

Demospongia

Calcipongiae

Euspongia

5. 12 g of an alkaline earth metal gives 14.8 g of its nitride. Atomic weight of that metal is

A)20

12

40

14.8

6. What form of nLcleotide represents the major currency of a cell?

Adenosine-5'-triphosphate

adenosine monophosphate

2'-O-Methyl-adenosine

Adenosine-5'-diphosphate monophosphate

7. At physiological pH, the carboxyl and amino groups in an amino acid are in the following form

-NH2

-COOH; NH2

-COOH; NH3+

NH3+

8. Which of the following animals reproduce asexually by fragmentation?

Nematodes

Sponges

Planarians

Echinoderms


9. Removal of the Bursa of Fabricius in a chick results in

Decrease in the number of T lymphocytes

Anemia

Delayed-type hypersensitivity

Low serum level of antibodies

10. Which of the following does not secrete steroid hormones?

Ovary

Pituitary

Testis

Corpus luteum


11. The enzymes which use the energy of ATP hydrolysis to move into and melt double-stranded DNA are

DNA ligase

DNA helicase

DNA primase

DNA polymerase

12. Calcltonin is secreted by

Thyrotrophs

Parafollicular C cells of thyroid

f3-cells of pancreas

Follicular or principal cells of thyroid

13. The conversion of sugar C12H22011-+ C02 is

Oxidation

Reduction

OXidation and reduction

Neutralization

14. A mixture of red and blue ink can be separated by

Distillation

Crystallization

Chromatography

Sublimation

15. The tertiary structure of a protein refers to the

presence of alpha-helices or beta-sheets

the sequence of amino acids

the unique three dimensional folding of the molecule.
interactions of a protein with other sub units or enzymes

16. The "satiety factors" that regulate food intake is

Peptin

Leptin

Statin

Pepsin

17. The atomic weight and atomic number of an element are A and respectively. The number of neutrons in the atom of that element is

A)A

B)Z

Z+A

A-Z

18. Susceptibility bacterium to duodenal ulcers is increased by an infection of the

Helicobacter pylori

Escherichia coli

Pseudomonas aeruginosa

Staphylococcus aureus

19. Cholecystokinin is secreted by

stomach

Liver

duodenum

Colon

20. The plants which produce only pollen or ovules are called

Dichogamous

Monoecious

Dioecious

Monogamous

21. The molarity of a solution containing 5.844 g of NaCI in 100 ml is

O.OlM

1M

O.lM

10M

22. The ability to hum a tune or recall a beautiful sunset in Kanyakumari is a function of

Cerebellum

Frontal lobe

Temporal lobe

Parietal lobe

23. Which of the following terms does l1QI refer to an example of a weak force of interaction between two biological molecules?

Covalent

Hydrophobic

Electrostatic

Hydrogen

24. C02 is mainly transported in the blood in one of the following forms:

Carbamino hemoglobin

Carbamino plasma protein

Dissolved C02

Bicarbonate

25. An enzyme acts by

decreasing the pH

increasing the pH

reducing the energy of activation

increasing the energy of activation

26. Coenzymes FMN and FAD are derived from

Vitamin C

Vitamin B6

Vitamin B1

Vitamin B2

27. Glucose is oxidized in the of cells.

Cytoplasm

Mitochondria

Chloroplast

Ribosomes

28. Shortage of acetylcholine in brain is associated with

Parkinson's disease

Alzheimer's disease

Huntington's disease

Schizophernia

29. In animals, the nervous system is derived from

ectoderm

Mesoderm

endoderm

Mesoendoderm

30. Regression of amphibian tail is under the Influence of

estrogens

Thyroxine

androgens

Insulin

31. All of the following are true with respect to IgE molecules, except

they are the principal immunoglobulin class involved in allergic reactions.

they are involved in mediating anti-parasitic immune responses.

they will cross the placenta and fix complement.

they can stimulate the release of histamine.

32. The percentage of oxygen in NaOH is

A)40

B)16

8

D)1

33. Which one of the following is an essential amino acid?

Alanine

Threonine

Aspartic acid

Glycine

34. The amino acid sequence of a peptide"Q-W-E-D" is

Tryptophan-Glutamine-Glutamate-Aspartate

Glutamine-Tryptophan-Aspartate-Glutamate

Glutamine-Tryptophan-Glutamate-Aspartate

Glutamate-Tryptophan-Glutamine-Aspartate

35. Biological oxidation in Kreb's cycle involves

A)N2

C02

02

502

36. Cyanide blocks the electron transport chain at

Cytochrome b

Cytochrome a+a3

Cytochrome c

Ubiquinone

37. The metal that can be extracted directly from sea water is

A)K

Mg

Zn

D)Ca

38. Which one of the following elements occurs free in nature?

Nitrogen

Phosphorous

Arsenic

Antimony

39. Fight or flight response is associated with

Catecholamines

Indoleamines

Opioid peptides

Acetylcholine

40. When AG is negative, the reaction is

exothermic

endothermic

hypothermic

ectothermic

41. Which of the following states that no two species can occupy the same niche indefinitely when resources are limiting?

Principle of resource limitation

Principle of species resourcing

Principle of competitive exclusion

Principle of competitive termination

42. The vector responsible for the transmission of Kala-azar is

House fly

Sand fly

Mosquito

Tsetse fly

43. The loss of an electron by a molecule is called

oxidation

enthalpy

reduction

enduced fit

44. White (fast-twitch) fibres differ from red (slow-twitch) fibres in having

a relatively large number of mitochondria and high ATPase activity

a relatively small number of mitochondria and low ATPase activity

a relatively small number of mitochondria and high ATPase activity

a relatively small number of mitochondria and low ATPase activity

45. Unsaturated fatty acids is present abundantly in

pulses

fish

meat

egg

46. Nitrous oxide, when inhaled in large quantities is fatal as it

is a neurotoxin

it binds to hemoglobin

it causes brain anoxia

it causes stroke

47. T vector cloning for a peR product requires

Polynucleotide kinase

Terminal transferase

Klenow DNA­ proof reading

Taq DNA polymerase polymerase

48. Tay-Sachs disease has clinical impact solely on

pancreas

liver

brain

kidney

49. Hydrophobic interactions are exhibited by

ions

hydration shells

polar molecules

non-polar molecules

50. Which of the following genotypes would produce largest variety of gametes if the alleles get assorted independently?

aaBBCcDd

AabbCCDD

AaBbCCDd

AABBCCDD

51. Ca+ released in response to a stimulus in the skeletal muscle binds to

troponin

tropomyosin

actin

Myosin

52. The key enzyme involved in gluconeogenesis is

pyruvate dehydrogenase

malate dehydrogenase

phosphenolpyruvate carboxykinase

hexokinase

53. The most serious and fatal form of anthrax is

pulmonary anthrax

gastrointestinal anthrax

cutaneous anthrax

ocular anthrax

54. A microbial culture started with 5 cells and reached to a density of 160 cells.
How many generations did the cells go through assuming no cell death occurred:

5

6

7

8

55. Which DNA polymerase in eukaryotes is involved in "Okazaki fragments" synthesis after the removal of RNA primer?

DNA polymerase ex

DNA polymerase E

DNA polymerase

DNA polymerase p

56. Which of the following is considered to be a fibrous protein?

Keratin

Immunoglobulin

Hemoglobulin

Myoglobulin

57. Where does endogenous fatty acid synthesis occur in humans?

Lactating mammary gland

Islets of Langerhans

Adipose tissue

Intestine

58. The extra embryonic membrane that gives protection to the developing embryo from shocks is

Yolk sac

Allantols

Chorion

Amnion

59. Which one of the following statements is correct with reference to ovoviviparity?

Ovoviviparity is restricted to few terrestrial forms.

Ovoviviparity is a common phenomenon in amphibians only.

Ovoviviparity is restricted to few exotic mammalian species.

Ovoviviparity is seen in a variety of aquatic forms, reptiles and invertebrates.


60. Which cellular structure in animal cells contain high amount of cholesterol?

Cellular/plasma membrane

Lysosomes

Endoplasmic reticulum

Nuclear membrane

61. Adrenaline produced by adrenal medulla is a

fatty acid

amines

peptide

steroid

62. Electron microscopes have greater resolving power than light microscopes because

the wavelength of electrons is much shorter than the wavelength of visible light

the wavelength of electrons is much longer than the wavelength of visible light

because the beams in electron microscopes overlap creating a clearer picture

electron microscopes have more lenses

63. In certain plants, the embryos in the seed may be produced asexually from the parent plant, which is known as

Monomixis

Polymixis

Holomixis

Apomixis

64. Athletes get muscle cramps due to

accumulation of lactic acid

sudden drop in myosin levels

respiratory problem

dehydration

65. The urea cycle occurs in the

mitochondria and cytoplasm

mitochondria and lysosome

endoplasmic reticulum and

Golgi complex and mitochondria peroxisomes

66. Spermatogenesis occurs in the

urlniriferous tubules

epididymis

seminal vesicles

seminiferous tubules

67. Superphosphate used as a fertilizer is:

Calcium phosphate

Ammonium phosphate

Calcium dihydrogen phosphate

Ammonium dihydrogen phosphate

68. In the treatment of asthma, the gases used are a mixture of

helium and oxygen

neon and oxygen

xenon and hydrogen

argon and oxygen

69. Assuming the half-life of a substance is S days, what will be the amount of the substance left after lS days if the initial amount is 64 grams?

4 gram

32 gram

8 gram

16 gram

70. In humans, the "Barr Body" is an

active X chromosome in females

active X chromosome in males

inactive Y chromosome in males

inactive X chromosome in female

71. Dry ice is

solid ice Without any water

solid sulphur dioxide

solid carbon dioxide

solid benzene

72. Treatment of root tip meristem cells with the microtubule inhibitor
colchicine results in all of the followinf except


induction of polyploidy

prevention of cytokinesis

inhibition of mitotic spindle

cessation of DNA replication assembly

73. A silent mutation in a gene results in

no change in the nucleotide sequence of mRNA encoded by the gene

no change in the amino. acid sequence of the protein

no expression of the protein encoded by the gene

a shift in the translational reading frame

74. "The descent of man" was the work done by

Alfred Russel Wallace

Charles Darwin

Malthus

Stephan Gould

75. Nuclides having the same atomic number are known as

isomers

isotopes

isobars

isotones

76. Two proteins of molecular masses of 120 kDa and 25 kDa can be easily separated by

size exclusion chromatography

affinity chromatography

ion exchange chromatography

adsorption chromatography

77. What process is used to convert vegetable oils into margarine and other solid or semisolid vegetable shortenings?

Bromination

Hydrolysis

Catalytic hydrogenation

Oxidation

78. Compound tubular glands found in the duodenum are known as

Brunner's gland

Bladin's gland

Cowper's gland

Ebner's gland

79. 90 g of water is equivalent to

6.02x1023

45

5

9X 102

80. Proteins synthesized by the rough ER are

for internal storage

only cytoplasmic proteinss

to build more membranes in the

exported from the cell cell

81. Heavy water is

H218O

B)D20

water obtained by repeated distillation

water at 4°C

82. The most reactive form of carbon is

Diamond

Graphite

Coal

Charcoal

83. What is the caloric value of protein meal per gram?

A)9

B)4

C)7

D)5

84. Cholesterol that is present in the blood serum is closely associated with

hardening of the arteries

kidney stones

Diabetes

Osteoporosis

85. In which of the following class of Subphylum Mandibulata, the head bears maxillae that are fused to form a plate-like structure called gnathochllarium?

Crustacea

Chilopoda

Insecta

Diplopoda

86. Which has maximum molecules?

7gN2

16g 02

2g H2

16g N02

87. The larvae of mosquito are example for

Neckton

Neuston

Hyponeuston

Epineuston

88. Sulphuric acid cannot be used

As a pickling agent

In lead storage batteries

In white paints

In manufacture of dyes

89. Which of the following is haVing strongest covalent bond?

H-CI

CI-CI

C-CI

Na-CI

90. Which of the following cell compartment is associated with a protein skeleton composed of lamins?

Basement membrane

Peroxisomes

Nucleus

Mitochondrion

91. Which of the following amino acid does not undergo phosphorylation?

Serine

Threonine

Tyrosine

Alanine

92. Transmembrane and secreted forms of immunoglobulins are generated from the same heavy chain gene by

rearrangement of DNA sequences

alternate splicing of mRNA transcript

proteolytic cleavage of the

post-translational modification of polypeptide polypeptide

93. Which of the following protein is not a part of the nucleosome?

A)H1

H2A

H3

D)H4

94. A patient with Klinefelter's syndrome will have the following chromosomes

44, XXX

44, XXV

45, XXV

44, XYV

95. Characteristics that have arisen as a result of common evolutionary descent are said to be

Analogous

Homologous

Hetererogamous

Contiguous

96. Lipopolysaccharide a potent inducer of cytokine synthesis is

endotoxin released by gram-negative bacteria

endotoxin released by gram-positive bacteria

exotoxin secreted by gram-negative bacteria

exotoxin secreted by gram-positive bacteria

97. The DNA from bacteriophage $X174 has base composition of 230/oA, 32% 30% G and 15% C. Which of the following best describes the phenomenon?

In viral genomes, the base pairing does not follow the standard Watson-Crick rule

Nucleic acids from viruses are tightly complexed with nucleic acid-binding proteins and they cannot base-pair with one another.

The genome of bacteriophage pie>X174 is single-stranded

Viral genomes are linear and tolerate base-pair mismatches


98. A second mutation in the same gene restores the wild type phenotype. This is known as

gene conversion

epistasis

intergenic complementation

intragenic suppression

99. When the alleles of a and a conform to Hardy-Weinberg expectations and if the frequency of a is 0.3, which of the following will be the most common genotype in the population?

A)A

aa

AA

Aa

100. While expressing an eUkaryotic gene in bacteria, eDNA is used rather than
genomic DNA, because

it is easier to clone cDNA than genomic DNA

cDNA is shorter in length

most eukaryotic gene promoters do not function in bacteria

most eukaryotic genes have introns that cannot be removed in bacteria