1. The complete aerobic respiration of glucose produces

Lactate and carbon dioxide

Water and oxygen

Water and carbon dioxide

Lactate and oxygen

2. The drug which selectiveIV Inhibits DNA polymerases and blocks DNA synthesis-

o-Amanitin

Aphidicolin

Actinomycin D

Rifampicin

3. The fetal placenta and umbilical cord are formed from the

Chorion amnion

Chorion endometrium

Chorion yolk sac

Chorion allantois

4. Gram positive cells have

A second outer membrane that helps to retain the crystal violet stain

A thick capsule that traps the crystal Violet stain

Multiple layer of peptidoglycan that help to retain the crystal violet stain

A periplasmic space that traps the crystal Violet stain


5. Which of the following techniques are used for the analysis of restriction fragment length polymorphisms?

Electrcphoresis chromatography

Restriction enzyme digestion chromatography

Methylation Restriction enzyme

Restriction enzyme digestion digestion electrophoresis

6. Lipid A stimulates the 8Ynthesls of which factor?

Transforming growth factor

Platelet derived growth factor (PDGF)

Epidermal growth factor

Tumor necrosis factor

7. The only living echinoderms which are fully sessile

Sea lilies

Sea cucumbers

Sand dollars

Sea urchins

8. Which one of the following agent is commonly used for determining the N­terminal amino acid of a polypeptide?

Trypsin

Cyanogen bromide

Phenyl Isothiocyanate

Aminopeptidase

9. The Michaells-Menten conatant Km is

Numerically equal to V2 Vmax

Independent of pH

Dependent on the enzyme concentration

Numerically equal to substrate concentration that gives half­maximal velocity

10. The unfertilized eggs laid by queen bee develop Into

Queens

Workers

Drones

Hermaphrodite

11. The chromosome composition seen in different syndromes Is given below. Identify the pair that Is mismatched.

Turner's syndrome -45

Down's syndrome Trisomy of 21st: chromosome

Kleinfelter's syndrome -47

Patau's syndrome Monosomy of 13th chromosome

12. Which one of the following sequences shows the correct hierarchy of classification, going from the moat inclusive to the least inclusive?

Kingdom, phylum, order, class,

Kingdom, phylum, class, order, family, genus, species family, genus, species

Kingdom, order, phylum, class,family, genus, species

Kingdom, class, order, family, genus, species

13. Silicon Is a

Insulator

Conductor

Semiconductor

Non-conductor

14. Which of the following disease Is not caused by bacteria?

Plague

Cholera

Yellow fever

Tuberculosis

15. If an affected male has all affected daughters, but no affected sons, the trait Is likely to be an

X-linked dominant trait

Autosomal recessive trait

Autosomal dominant trait

X-linked recessive trait

16. The molarity of a solution containing 5.844 gram NaCIIn 100 mL Is

0.01M

0.1M

1M

10M

17. The phylum of plants that Includes mosses is

Anthocerophyta

Bryophyta

Lycophyta

Pterophyta

18. The premature aging syndrome caused due to the mutation In DNA repair en%Vmes Is

Hutchinson-Gilford Progeria

Dementia

Aphasia

Schizophrenia

19. Which one of the following pairs are analogous structures?

The front leg of horse and a human arm

The front leg of frog and a bat wing

The front nipper of a whale and a human arm

The wings of bird and butterfly wings

20. Hydrolysis of one ATP molecule to ADP releases __calories of energy.

730

7,300

68,600

73,000

21. Which one of the following DNA duplex has highest melting temperature?

ATGGCTCGT TACCGAGCA

GGCTGGAGA CCGACCTCT

ATGGGCCCTG TACCCGGGAC

ATGATACTG TACTATGAC

22. Receptors for which of the following hormones are found In the cytoplasm of responsive cells?

Thyroid hormone and insulin

Glucagon and estrogen

Insulin and estrogen

Thyroid hormone and estrogen

23. The cooking time for food is reduced in a pressure cooker because

Heat Is more evenly distributed In the cooking space

Boiling point of the water involved In cooking is increased

The higher pressure Inside the cooker pulverizes the food material

Bolling point of the water Involved In cooking Is decreased

24. The animals that are genetically constructed to differ at one particular locus are called as

Chimeric

Congenic

Hybrid

Transgenic

25. sequencing and analysis of rRNA has divided the living world Into three domains celled

Bacterta, archaea eukarya

Archaea, eukarya virus

Fungi, plants and animals

Bacteria, archaea &. plants

26. A process In which movement of a molecule across the membrane down Its concentration gradient Is coupled to the movement of a second molecule up Its concentration gradient and across the membrane In opposite direction Is Called

Active transport

Uniport

Antiport

Symport

27. The matrix of mitochondria contains

A high concentration of glucose

FAOH,

Citric acid cycle Intermediates

Glycogen

28. Planarian use for.......... excretion

Flame cells

Nephridia

Uriniferous tubules

Malpighlan tubules

Z9. The occurrence of tetratype In the acetomycate fungi Is possible only If the crossing over occurred during the

Four-strand stage

Gl phase

Two-strand stage

S phase

30. In mammals, the diaphragm separates the

Thoracic cavity from the pericardial

Peritoneal cavity from the thoracic cavity cavity

Peritoneal cavity from pericardial cavity

D)Thoracic cavity from the pelvic cavity

31. Which one of the following metabolites Is not directly produced In the hexose monophosphate shunt pathway?

Fructose-6-phosphate

Dihydroxyacetone phosphate

Erythrose-4-phosphate

Gluconolactone-6-phosphate

32. Cytochromes are found In

Inner mitochondrial membrane

Cristae of mitochondria

Matrix of mitochondria

Outer mitochondrial membrane

33. Tapeworms attach to the digestive lining of the heft by means of their

Proglottid

Stylete

Mastax

Scolex

34. If the paternal chromosomes have alleles c and the maternal chromosomes have C -then the chromosomes that are not a product of crossing over are

ABC and abc

AbC and aBc

Abc and aBC

ABc and abC

35. Nondisjunction involving the X chromosomes may occur during oogenesis and produce two kinds of eggs. If normal sperms fertilize these two types, which of the following pairs of genotypes are possible?

XXandXV

XXVandXO

XXVandVO

XXandXO

36. Methionyl-transfer RNA is used for initiation of protein synthesis by which of the following?

Chloroplast

Eukaryotic cytoplasmic ribosomes

Bacterial ribosomes

Eukaryotic mitochondrial ribosomes

37. Which component in the viral envelope attaches the human deficiency virus to host cells?

gp41

p18

gp120

p24

38. Which one of the following could be used to distinguish between an aidose and a ketose?

Br2 water

Tollen's reagent

Fehling's reagent

Feulgen's reagent

39. Common method used for determination of the three dimensional structure of proteins is

Edman degradation

MALDI TOF analysis

X-ray crystallography

Two dimensional gel electrophoresis

40. Which one of the following is correct?

Animal cells produce cellulase which hydrolyze cellulose

Carbohydrates are absorbed primarily in the form of disaccharides

Glycogen hydrolysis Is promoted by the hormone glucagon

Insulin has lIttle effect on carbohydrate metabolism

41. If a phosphodiester bond in one strand of double stranded circular DNA Is broken, the DNA is said to be

Digested

Linearized

Nicked

Cleaved

42. The first virus to be purified was

Influenza virus

Tobacco Mosaic virus

Polio virus

Smallpox

43. The amino acid leucine has the following side chain.

CH3-CH

(CH3)2-CH-CH2



CH3-CH2-CH(CH3)-

44. Which one of the following is NOT a pert of the Immune system?

Spleen

Thymus

Tonsil

Pancreas

45. Liebermann's reaction Is used for detection of

aniline

benzoic acid

nitrobenzene

phenol

46. When an animal cell Is placed In 0.5 M sucrose solution, its volume does not alter. When the same cell Is transferred to a 0.5 M NaCI solution, the volume of the cell will

Remain unchanged

Decrease

Increase

Increase and then decrease

47. Which one of the following is mistmatched?

Matrix -extracellular material In connective tissue

cardiac muscle cells -multiple nuclei

Adipose cells found In loose connective tissue

Ligaments -bind muscles to bone

48. The nucleic acid which is highly modified by extensive methylation after synthesis Is

hnRNA

mRNA

tRNA

rRNA

49. Which on. of the following Is an acidic amino acid?

Aspartic acid

Isoleucine

Lysine

Proline

50. Genetic recombination In bacteria occurs through the transfer of

Pili

Plasmids

Endospores

Gametes

51. The second messenger which plays a crucial role In regulating the synthesis and breakdown of glycogen in liver and muscle cells Is

cAMP

cGMP

DAG

IP3

52. What blocks myosin from binding to actin, when the muscle Is at rest?

Acetylcholine

ATP

Tropanin

Tropomyosin

53. Which one of the following Is not a cancer drug?

Isoniazid

Clsplatln

Methotrexate

Daunorubicin

54. Isotypes defer to variation In the

Light chain variable region

Light chain constant region

Heavy chain variable region

Heavy chain constant region

55. When chromosome breakage occurs and the broken segment route. by 180degrees before reunion, the resulting chromosome aberration Is known as

Insertion

Translocation

Inversion

Frame shift

56. A common method for separating soluble proteins Is

Filtration

Column chromatography

Polyacrylamide gel electrophoresis

Differential centrifugation

57. Cystic fibrosis is caused by____mutation,

Autosomal recessive

Autosomal dominant

Sex-linked recessive

Sex-linked dominant

58. In sensory neurons, stimuli are conducted through

Axons

Dendrites

Cell body

Myelin sheath

59. According to molecular definition of a gene, which one of the following Is not a part of eukaryotlc gene?

Promoter

Poly tail

Enhancer

Polyadenylation signal

60. At room temperature formaldehyde changes' into

Trloxane

Paraldehyde

Acetaidehyde

Acetic acid

61. Which one of the following is part of the gynoecium?

Filament

Carpel

Stamen

Sepal

62. The major class of Insoluble fibrous protein present In the extracellular matrix and In connective tissue Is

Actin

cadherin

Fibronectin

Collagen

63. The following method helps In determining the genotype of an IndivIdual for a particular trait

Test crOSS

Back cross

Dihybrid cross

Monohybrid cross

64. The rhythmic beatIng of the heart Is initiated by the

Purklnje fibers

Bundle of His

Atrioventricular node

Sinoatrial node

65. Which one of the following is an Innate immune cell type?

B lymphocyte

T lymphocyte

Macrophage

NKT cells

66. Which one of the following Is not characteristic of members of the plant kingdom?

carotenoids

Chlorophyll c

Chlorophyll a

Chlorophyll b

67. Releasing hormones GnRH etc.) in higher animals are synthesized and secreted by

Adenohypophysis

Neurohypophysis

Hypothalamus

Pars-Intermedia

68. The neurotransmitter at the neuromuKular junction is·

Dopamine

Serotonin

Acetyl choline

Epinephrine

69. Which one of the following is not a primary alcohol?

Methanol

Ethanol

Benzyl alcohol

Isopropyl alcohol


70. Green algae, recently been investigated as food source in several nations Is

Volvox

Chlorella

Chlamydomonas

Pseudomonas

71. The virus commonly used for the management of Insect pests as well as a vector for production of recombinant proteins is

Retrovirus

Adenovirus

Parvovlrus

Baculovirus

72. Two antagonistic hormones are'"

MSH TSH

Calcitonin Parathormone

ADH GH

Oxytocin Prolactin

73. Which has the maximum percentage of CI?

Neoprene

PVC

BHC

DOT


74. The Inflammatory response include. all of the following except

Vessel constriction

Temperature increase

Increased blood flow

Phagocytic attack

75. Worlds natural gas reservoirs are primarily produced by

Anaerobic fungi

Actinomyces

Primitive protists

Archaebacteria


76. Components of animal cell cytoskeleton found In cilia and flagella that direct chromosomal movement during cell division are

Microtubules

Microftlaments

Intermediary filaments

Microtubules and microfilaments

77. Solid CO, Is an example of

Ionic crystal

Metallic crystal

Covalent crystal

Molecular crystal

78. The following are epimers of glucose

Galactose and fructose

Mannose and galactose

Mannose and fructose

Sucrose and fructose

79. Enzymes from the following organelle are Involved In the oxidation of fatty acids, but the released energy Is not used for ATP synthasis

Mitochondria

Lysosomes

Peroxisomes

Ribosomes

80. While most of the Insects have four wings, the following have only two

Cockroach

Houseny

Butterfly

Honeybee

81. Enzyme produced in the kidney, which catalyzes the cleAvAge of anglotenslnogen present In the blood-

Angiotensin

Bradykinin

Kynurenine

Renm

82. Cerebellum regulates

Body Temperature

Movement and balance

Sleep-wake cycle

Learning and memory

83. If radioactive SUlphur is added to culture medium of E. COli, the radioactive label after 48 hours will be localized In

Enzymes

RNA

DNA

Phosphoilpid

84. Vertebrate lungs are derived from

Ectoderm

Epiderm

Endoderm

Mesoderm

85. Glucokinase

Is widely distributed in most of the

Has high Km for glucose mammalian tissues

Is inhibited by glucose-6-phosphate

catalyzes a reversible reaction

86. Humans can digest starch and not cellulose. Both of them contain monomeric glucose units. Starch is digested due to specificity of the intestinal enzymes for

linkage

beta linkage

0 linkage

beta linkage

87. Drugs that prevent the formation of bacterial cell wall are

quinoiones

beta-Iactams

tetracycline

Aminoglycosldes

88. Heat shock proteins, originally identified as proteins expressed in response to stress, also function as

Protein kinase

GTPase activating proteins

Proteases degrading ubiquitin­tagged proteins

Molecular chaperones, which assist in de novo protein folding

89. When a lead storage battery Is discharged

SO, is evolved

Lead sulfate Is consumed

Lead is formed

Sulphuric acid is consumed

90. The genome of an organism contains 20% adenIne residue. Which one of the following statement Is correct?

G+C content is 20%

G C content Is 40%

G C content is 60%

G C content is 80%

91. If one mL of 0.01 M HCI is diluted to 100 mL at 25° what will be the pH of tile resulting solution?

A)2

B)4

C)5

D)7

92. Which one of the following pathway Is very active in the tissues Involved In lipogenesis and nucleic acid biosynthesis?

Glycolysis

TCA cycle

beta oxidation

HMP shunt pathway

93. Which one of the followIng Is a human cell line?

CHO

Hela

BHK-21

Sf-9

94. When a gasoline Is given "octane number" 80, It means it contains

80% octane

80% iso-octane

20% iso-octane

20% benzene

95. The bacteria which utilize CO, as the sole carbon source and obtains energy by oxidation and reduction of inorganic substances are called as

Chemolithotrophs

Photoautotrophs

Chemoheterotrophs

Photoheterotrophs

96. Human albinism is caused by recessive gene A child has albinism, although
none of the parents are affected, What Is the genotype of parents?

AA and AA

Aa and AA

Aa and Aa

Aa and aa

97. Viral replication within cells is Inhibited by

IL-1

IL-4

IFN-y

TNF-a

98. In the mitochondrial genome, the stop codon Is

AGA

UGA

UUU

UAA

99. Which one of the following Is a polyatomic cation?

Mg2+

NH4+

Cu2+

OH-

100. Human embryonic Rem cells are commonly derived from

Complete blastocyst

Trophoblast

Inner cell mass

Cord blood cells