Answer any three questions. Each question carries 10 marks:

1. Define and classify hypersensitivity, write a short note on anaphylaxis.

2. Describe in detail about the structure, function of T cell and B cell lymphocytes.

3. Define immune response. Describe about humoral immune response.

4. Describe in detail principle, procedure and interpretation of Widal test in diagnosis of various types of enteric fever.

5. Write in brief on any four of the following:

Ig G

VDRL Test

Structure of immunoglobulins

Passive immunity

Interleukins

6. Write short answers on

Antibody

List two difference between active and passive immunity

Coombs and Gel classification

Live vaccine

Flocculation Test

7. Write True/False for the following:

Hapten is a complete antigen.

Widal test is an example for precipitation reaction.

BCG vaccine is an example for live vaccine.

Primary response is slow, sluggish and short lived.

Immunoglobulin classes are determined by L chains.

8. Fill in the blanks by choosing the appropriate from the following:

Weil-Felix reaction is in serodiagnosis of

typhus fever

typhoid fever

Trimolecular complex C 567 of complement system is

heat labile

heat stable

Tuber culin test is an example for hypersensitivity.

Type II

Type IV

In agglutination reaction type of antigen is involved.

particulate

soluble

immunoglobulin is the only maternal antibody to transport across the placenta.

Ig M

Ig G