Exam Details
| Subject | bioinformatics | |
| Paper | ||
| Exam / Course | m.tech | |
| Department | ||
| Organization | central university | |
| Position | ||
| Exam Date | 2016 | |
| City, State | telangana, hyderabad |
Question Paper
1. Ribozymes are
Non proteinaceous part of an enzyme
Nucleic acids behave as enzymes
Metal-cofactor associated with an enzyme
Secondary structure of protein
2. If y ln(5-x),then dy/dx=
3. What is stderr
standard error
standard error types
standard error streams
standard error definitions
4. One of the following NGS methods can cover a full bacterial genome in a single read
Heliscope
PacBio
Solexa
Ion Proton
5. Specify the 2 library functions to dynamically allocate memory?
malloc() and memalloc().
alloc() and memalloc().
malloc() and calloc()
memalloc() and faralloc()
6. Copper is present in
Plasmalemma
Plastoquinone
Cytochrome oxidase
Ferredoxin
7. Find the value of 12.362 X 0.587 (with appropriate significant figures)
7.2565
7.257
7.26
7.3
8. Which of the following statements should be used to obtain a remainder after dividing 3.14 by 2.1?
rem 3.14 2.1;
rem modf(3.l4,
rem fmod(3.14,
Remainder cannot be obtain in floating point division.
9. Which of the following arrangement of materials in terms of their electrical resistivity is correct?
Quartz> Graphite> Mercury> Copper
Copper> Mercury> Graphite> Quartz
Copper> Mercury> Quartz> Graphite
Mercury >Copper Graphite> Quartz
10. To determine sequence coverage, one needs to know
Genome size, read length and number of reads
Genomic DNA concentration and number of sequenced clones
Source of DNA, number of repeat regions and G+C content
All of the above
11. Which one of the following vector is perpendicular to
12. The following algorithm/method has applications in genome assembly
Morkov Chain Monte Carlo
Smith-Waterman
Posterior probability
deBruijn graph
13. A dice is rolled 30 times. What is the mean value for appearance of the numbers other than
6
20
25
30
14. What is the molarity of 10.6% sodium carbonate solution?
100 mM
1000 mM
500 mM
106 mM
15. Identify from the following enzyme which is NOT used in the isolation of the genetic material
Lysozyme
Cellulase
Chitinase
Polymerase
16. Identify number of primary carbon atoms present in
CH3 CH3
H3C C C CH3
CH3 CH3
2
6
3
8
17. Reactivity order of halogen acids with an alkyl group
HCl HBr HI·
HI HBr HCl
HBr HI HCl
HCl HBr HI
18. How many sigma and pi bonds are present in n1,3-Butadiene
9 and 1
9 and 2
11 and 0
10 and 0
19. An elevator (lift) weighing 1000kg can carry a weight of 100 kg and it faces the frictional force of 1000 N during its upward movement. What is the power required to move the elevator upwards with a constant velocity of 2
4,200 W
19,560 W
21,560 W
23,560 W
20. Is there any difference between following declarations?
extern int
int
Both are identical
No difference, except extern int is probably in another file
int is overrided with extern int
None of these
21. The following virus can be stained by Gram's staining
Mimivirus
Picoma Virus
Lyssa Virus
Polyoma Virus
22. Which one of the following contains ester bond?
Triglyceride
Glycerol
Glucose
Maltose
23. In general, for the data distribution to the right
mean median mode
mean mode median
median mean mode
mode median mean
24. A ds DNA of E. coli in which both the strands were labelled with heavy isotope was transferred in to the medium with 14NH4Cl. This DNA undergoes replication per every 20 minutes. After 80 minutes what is the percentage of DNA with 14N and 15N respectively
50% and 50%
93. 73% and 6.25%
87.5% and 12.5%
75% and 25%
25. What kind of hybrid orbitals are utilized by the carbon atom in CF4 molecules?
sp
Sp².
Sp³
sp³d
26. How would you round off a value from 1.66 to 2.0?
ceil(1.66)
floor(1.66)
roundup(1.66)
roundto(1.66)
27. Which of the following is a bacterium involved in denitrification?
Nitrococcus
Nitrosomonas
Pseudomonas
Nitrobacter
28. Find the matrix X in
3 2
x
3 1 3
5 4
13 9
11 5
8 3
11
2 -15
10
7
29. lim tan x x
0
1
infinity
30. An electromagnetic wave which travels with the frequency of 50 Hz has electric field of 7.2 Vim at a certain point in space arid time: The magnetic field at the point is,
2. 4x 10^8 T
2. 16 X 10^9T
1.08 X10^11 T
360 T
31. The point dividing a line created by the points and in the ratio of 2:3 is
1.2)
32. 3.65 g of HCl is dissolved in 16.2 g of water. Calculate the mole fraction of HCl.
1
3.65
0.1
4.43
33. A cell increases in size when placed in a n external solution, which is
Hypotonic
Hypertonic
Isotonic
Higher solute concentrated solution
34. Which of the following function is the solution of the equation: d²y/dx² 2 dy/dx -3y
e^2x
e^3x
35. A ball of mass 10g is freely released in vessel containing oil such that the resistive force the ball experience is proportional to its speed If the time constant is 0.1 the terminal speed of the ball will be, 9.8
0.98 cm/s
9.8 cm/s
98 cm/s
980 cm/s
36. A genome size of 3.5 Mb signifies which organism?
Yeast
Bacterium
Microfilaria
Virus
37. A 2 m string with the weight of 50g is under the tension of ION. The speed of transverse wave on the wire would be
10 m/s
16 m/s
20 m/s
40 m/s
38. What are the types of linkages?
Internal and External
External; Internal and None
External and None
Internal
39. One of the following questions regarding ecosystem functioning can't be addressed by Metagenomics .
Who are there?
What are they doing?
Do they interact?
How long they have been there?
40. Which of the following special symbol allowed in a variable name?
*(asterisk)
|(pipeline)
-(hyphen)
(underscore)
41. Is the following statement a declaration or definition? extern int
Declaration
Definition
Function
Error
42. Which of the following is a natural auxin?
Indole butyric acid
2,4-Dichlorophenoxy acetic acid
Indole -3-acetic acid
Naphthalene acetic acid'
43. The keyword used to transfer control from a function back to the calling function is
switch
goto
go back'
return
44. The initiation codon generally present atS'end ofmRNA is
AUC
AUG
GUC
UUU
45. In if you pass an array as an argument to a function, what actUally gets passed?
Value of elements in array .
First element of the array
Base address of the array
Address of the last element of array
46. The bacteria which capture light energy and transform it into chemical energy and obtain carbon from atmospheric carbon dioxide are called
Photoheterotrophs
Photoautotrophs
Chemoheterotrophs
Chemoautotrophs
47. What is the percentage of adenine in a DNA molecule of 85 A° length having 10 thymine molecules
10%
30%
15%
20%
48. What will the function rewind() do?
Reposition the file pointer to a character reverse.
Reposition the file pointer stream to end of file.
Reposition the file pointer to begining of that line.
Reposition the file pointer to begining of file.
49. Input/output function prototypes and macros are defined in which header file?
conio.h
stdlib.h
studio.h
dos.h
50. The point of intersection between the curves y x-l and y x²-2x-l is
51. Which of the following is a tricarboxylic acid?
Malic acid
Oxalo acetic acid
Citric acid
a-ketoglutaric acid
52. A mutation in the trp binding. site of the repressor would result in
constitutive trp operon expression
inducible trp operon expression
no operon expression
none of the above
53. Which standard library function will you use to find the last occurance of a character in a string in
strncharO
strcharO
strrcharO
strrchrO
54. What will the function randomizeO do in Turbo C under DOS?
returns a random number.
returns a random number generator in the specified range.
returns a random number generator with a random value based on time.
return a random number with a given seed value.
55. The number of bacteria produced after two hours if a parental bacterium divides by binary fission for every twenty minutes
8
16
32
64
56. In which stage the following code #include<stdio.h> gets replaced by the contents of the file stdio.h
During editing
During linking
During execution
During preprocessing
57. Which of the following is not a type of signaling molecule?
Testosterone
Insulin
Thyroxin
Adenylate cyclase
58. Which header file should be inCluded to use functions like"malloc() and callocO?
memory.h
stdlib.h
string.h
dos.h
59. Acyl carrier protein plays an important role in the biosynthesis of
fatty acids
amino acids
sugars
carbohydrates
60. What function should be used to free the memory allocated by callocO
dealloc();
malloc(variable_name,())
memalloc(variable_name,())
61. What will happen if in a C program you assign a value to an array element whose subscript exceeds the size of array?
The element will be set to 0.
The compiler would report an error.
The program may crash if some important data gets overwritten.
The array size would appropriately grow.
62. Which of the following is symbolic representation of a monohybrid back cross
Tt x TT
TT x tt
Tt x tt
Tt x Tt
63. How will you free the allocated memory?
remove(var-name);
free(var-name);
delete(var-name);
dalloc(var-name);
64. The additional OH group of every nucleotide. of RNA is bonded to
3rd carbon position of deoxy ribose sugar .
5th carbon position of deoxy ribose sugar
2nd carbon position of ribose sugar
5th carbon position of ribose sugar
65. Which of the following is a keyword in C language?
signed
integer
floater
main()
66. The hydrolysis of "Lactose" is catalyzed by
permease
transacetylase
beta-galactosidase
primase
67. Which of the following is not a valid relational operator
68. Substitution of which one of the following amino acid with serine during the course of molecular evolution is readily acceptable and is a conservative substitution?
Cysteine
Tryptophan
Proline
Threonine
69. Diamond symbol in Flow chart represents
Process
Decision
Input/output
Termination
70. What is the purpose of fflush() function.
flushes all streams and specified streams.
flushes only specified stream.
flushes input/output buffer.
flushes file buffer.
71. For the better resolution -of minute protein bands in. SDS-PAGE, which of the following staining method is advised?
CBB Staining
Silver staining
Avidin staining
All of these
72. Which of the following techniques is used to-study the three-dimensional structure of a molecule?
Mass spectrometry
UV-visible spectroscopy
Infra-red spectroscopy
X-ray crystallography
73. How many milliliters of a 200 mM HCl solution are required to bring the pH of 10 milliliters of a 200 mM NaOH solution to 7.0
4
40
10
20
74. Small cDNA sequence that represents a unique segment of an active gene is called
SNP
SnRNA
EST
Contig
75. Which of the following language is associated with slogan 'write once run anywhere'.
JAVA
C
FORTRAN
COBOL
Non proteinaceous part of an enzyme
Nucleic acids behave as enzymes
Metal-cofactor associated with an enzyme
Secondary structure of protein
2. If y ln(5-x),then dy/dx=
3. What is stderr
standard error
standard error types
standard error streams
standard error definitions
4. One of the following NGS methods can cover a full bacterial genome in a single read
Heliscope
PacBio
Solexa
Ion Proton
5. Specify the 2 library functions to dynamically allocate memory?
malloc() and memalloc().
alloc() and memalloc().
malloc() and calloc()
memalloc() and faralloc()
6. Copper is present in
Plasmalemma
Plastoquinone
Cytochrome oxidase
Ferredoxin
7. Find the value of 12.362 X 0.587 (with appropriate significant figures)
7.2565
7.257
7.26
7.3
8. Which of the following statements should be used to obtain a remainder after dividing 3.14 by 2.1?
rem 3.14 2.1;
rem modf(3.l4,
rem fmod(3.14,
Remainder cannot be obtain in floating point division.
9. Which of the following arrangement of materials in terms of their electrical resistivity is correct?
Quartz> Graphite> Mercury> Copper
Copper> Mercury> Graphite> Quartz
Copper> Mercury> Quartz> Graphite
Mercury >Copper Graphite> Quartz
10. To determine sequence coverage, one needs to know
Genome size, read length and number of reads
Genomic DNA concentration and number of sequenced clones
Source of DNA, number of repeat regions and G+C content
All of the above
11. Which one of the following vector is perpendicular to
12. The following algorithm/method has applications in genome assembly
Morkov Chain Monte Carlo
Smith-Waterman
Posterior probability
deBruijn graph
13. A dice is rolled 30 times. What is the mean value for appearance of the numbers other than
6
20
25
30
14. What is the molarity of 10.6% sodium carbonate solution?
100 mM
1000 mM
500 mM
106 mM
15. Identify from the following enzyme which is NOT used in the isolation of the genetic material
Lysozyme
Cellulase
Chitinase
Polymerase
16. Identify number of primary carbon atoms present in
CH3 CH3
H3C C C CH3
CH3 CH3
2
6
3
8
17. Reactivity order of halogen acids with an alkyl group
HCl HBr HI·
HI HBr HCl
HBr HI HCl
HCl HBr HI
18. How many sigma and pi bonds are present in n1,3-Butadiene
9 and 1
9 and 2
11 and 0
10 and 0
19. An elevator (lift) weighing 1000kg can carry a weight of 100 kg and it faces the frictional force of 1000 N during its upward movement. What is the power required to move the elevator upwards with a constant velocity of 2
4,200 W
19,560 W
21,560 W
23,560 W
20. Is there any difference between following declarations?
extern int
int
Both are identical
No difference, except extern int is probably in another file
int is overrided with extern int
None of these
21. The following virus can be stained by Gram's staining
Mimivirus
Picoma Virus
Lyssa Virus
Polyoma Virus
22. Which one of the following contains ester bond?
Triglyceride
Glycerol
Glucose
Maltose
23. In general, for the data distribution to the right
mean median mode
mean mode median
median mean mode
mode median mean
24. A ds DNA of E. coli in which both the strands were labelled with heavy isotope was transferred in to the medium with 14NH4Cl. This DNA undergoes replication per every 20 minutes. After 80 minutes what is the percentage of DNA with 14N and 15N respectively
50% and 50%
93. 73% and 6.25%
87.5% and 12.5%
75% and 25%
25. What kind of hybrid orbitals are utilized by the carbon atom in CF4 molecules?
sp
Sp².
Sp³
sp³d
26. How would you round off a value from 1.66 to 2.0?
ceil(1.66)
floor(1.66)
roundup(1.66)
roundto(1.66)
27. Which of the following is a bacterium involved in denitrification?
Nitrococcus
Nitrosomonas
Pseudomonas
Nitrobacter
28. Find the matrix X in
3 2
x
3 1 3
5 4
13 9
11 5
8 3
11
2 -15
10
7
29. lim tan x x
0
1
infinity
30. An electromagnetic wave which travels with the frequency of 50 Hz has electric field of 7.2 Vim at a certain point in space arid time: The magnetic field at the point is,
2. 4x 10^8 T
2. 16 X 10^9T
1.08 X10^11 T
360 T
31. The point dividing a line created by the points and in the ratio of 2:3 is
1.2)
32. 3.65 g of HCl is dissolved in 16.2 g of water. Calculate the mole fraction of HCl.
1
3.65
0.1
4.43
33. A cell increases in size when placed in a n external solution, which is
Hypotonic
Hypertonic
Isotonic
Higher solute concentrated solution
34. Which of the following function is the solution of the equation: d²y/dx² 2 dy/dx -3y
e^2x
e^3x
35. A ball of mass 10g is freely released in vessel containing oil such that the resistive force the ball experience is proportional to its speed If the time constant is 0.1 the terminal speed of the ball will be, 9.8
0.98 cm/s
9.8 cm/s
98 cm/s
980 cm/s
36. A genome size of 3.5 Mb signifies which organism?
Yeast
Bacterium
Microfilaria
Virus
37. A 2 m string with the weight of 50g is under the tension of ION. The speed of transverse wave on the wire would be
10 m/s
16 m/s
20 m/s
40 m/s
38. What are the types of linkages?
Internal and External
External; Internal and None
External and None
Internal
39. One of the following questions regarding ecosystem functioning can't be addressed by Metagenomics .
Who are there?
What are they doing?
Do they interact?
How long they have been there?
40. Which of the following special symbol allowed in a variable name?
*(asterisk)
|(pipeline)
-(hyphen)
(underscore)
41. Is the following statement a declaration or definition? extern int
Declaration
Definition
Function
Error
42. Which of the following is a natural auxin?
Indole butyric acid
2,4-Dichlorophenoxy acetic acid
Indole -3-acetic acid
Naphthalene acetic acid'
43. The keyword used to transfer control from a function back to the calling function is
switch
goto
go back'
return
44. The initiation codon generally present atS'end ofmRNA is
AUC
AUG
GUC
UUU
45. In if you pass an array as an argument to a function, what actUally gets passed?
Value of elements in array .
First element of the array
Base address of the array
Address of the last element of array
46. The bacteria which capture light energy and transform it into chemical energy and obtain carbon from atmospheric carbon dioxide are called
Photoheterotrophs
Photoautotrophs
Chemoheterotrophs
Chemoautotrophs
47. What is the percentage of adenine in a DNA molecule of 85 A° length having 10 thymine molecules
10%
30%
15%
20%
48. What will the function rewind() do?
Reposition the file pointer to a character reverse.
Reposition the file pointer stream to end of file.
Reposition the file pointer to begining of that line.
Reposition the file pointer to begining of file.
49. Input/output function prototypes and macros are defined in which header file?
conio.h
stdlib.h
studio.h
dos.h
50. The point of intersection between the curves y x-l and y x²-2x-l is
51. Which of the following is a tricarboxylic acid?
Malic acid
Oxalo acetic acid
Citric acid
a-ketoglutaric acid
52. A mutation in the trp binding. site of the repressor would result in
constitutive trp operon expression
inducible trp operon expression
no operon expression
none of the above
53. Which standard library function will you use to find the last occurance of a character in a string in
strncharO
strcharO
strrcharO
strrchrO
54. What will the function randomizeO do in Turbo C under DOS?
returns a random number.
returns a random number generator in the specified range.
returns a random number generator with a random value based on time.
return a random number with a given seed value.
55. The number of bacteria produced after two hours if a parental bacterium divides by binary fission for every twenty minutes
8
16
32
64
56. In which stage the following code #include<stdio.h> gets replaced by the contents of the file stdio.h
During editing
During linking
During execution
During preprocessing
57. Which of the following is not a type of signaling molecule?
Testosterone
Insulin
Thyroxin
Adenylate cyclase
58. Which header file should be inCluded to use functions like"malloc() and callocO?
memory.h
stdlib.h
string.h
dos.h
59. Acyl carrier protein plays an important role in the biosynthesis of
fatty acids
amino acids
sugars
carbohydrates
60. What function should be used to free the memory allocated by callocO
dealloc();
malloc(variable_name,())
memalloc(variable_name,())
61. What will happen if in a C program you assign a value to an array element whose subscript exceeds the size of array?
The element will be set to 0.
The compiler would report an error.
The program may crash if some important data gets overwritten.
The array size would appropriately grow.
62. Which of the following is symbolic representation of a monohybrid back cross
Tt x TT
TT x tt
Tt x tt
Tt x Tt
63. How will you free the allocated memory?
remove(var-name);
free(var-name);
delete(var-name);
dalloc(var-name);
64. The additional OH group of every nucleotide. of RNA is bonded to
3rd carbon position of deoxy ribose sugar .
5th carbon position of deoxy ribose sugar
2nd carbon position of ribose sugar
5th carbon position of ribose sugar
65. Which of the following is a keyword in C language?
signed
integer
floater
main()
66. The hydrolysis of "Lactose" is catalyzed by
permease
transacetylase
beta-galactosidase
primase
67. Which of the following is not a valid relational operator
68. Substitution of which one of the following amino acid with serine during the course of molecular evolution is readily acceptable and is a conservative substitution?
Cysteine
Tryptophan
Proline
Threonine
69. Diamond symbol in Flow chart represents
Process
Decision
Input/output
Termination
70. What is the purpose of fflush() function.
flushes all streams and specified streams.
flushes only specified stream.
flushes input/output buffer.
flushes file buffer.
71. For the better resolution -of minute protein bands in. SDS-PAGE, which of the following staining method is advised?
CBB Staining
Silver staining
Avidin staining
All of these
72. Which of the following techniques is used to-study the three-dimensional structure of a molecule?
Mass spectrometry
UV-visible spectroscopy
Infra-red spectroscopy
X-ray crystallography
73. How many milliliters of a 200 mM HCl solution are required to bring the pH of 10 milliliters of a 200 mM NaOH solution to 7.0
4
40
10
20
74. Small cDNA sequence that represents a unique segment of an active gene is called
SNP
SnRNA
EST
Contig
75. Which of the following language is associated with slogan 'write once run anywhere'.
JAVA
C
FORTRAN
COBOL