Exam Details
| Subject | advanced organic chemistry (262905) | |
| Paper | ||
| Exam / Course | m.pharm. | |
| Department | ||
| Organization | Dr.M.G.R. Medical University | |
| Position | ||
| Exam Date | May, 2019 | |
| City, State | tamil nadu, chennai |
Question Paper
THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LO 344] MAY 2019 Sub. Code: 2905
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH II PHARMACEUTICAL CHEMISTRY
PAPER II ADVANCED ORGANIC CHEMISTRY
Q.P. Code: 262905
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Explain the mechanism and stereo-chemistry of aliphatic nucleophilic substitution
and aromatic electrophilic substitution reaction.
2. Classify heterocyclic compounds with examples. Write the preparation and
properties of a fused ring structure containing hetero atom.
Write in brief about nitrenes.
II. Write notes on: (10 x 6 60)
1. How are chiral drugs prepared? Mention the importance of chiral drugs.
2. Synthones for carbon-carbon bond formation.
3. Types of Pericyclic reactions with examples.
4. Concepts of Nanochemistry.
5. Write the mechanism of Michael reaction. Mention its applications.
6. What is parallel synthesis? Give an example.
7. Write a note on addition reactions with examples.
8. How is an aldehyde group protected during organic synthesis?
9. Explain the generation, fate and biological significance of free radicals.
10. Discuss in detail the mechanisms involved in elimination reactions.
[LO 344] MAY 2019 Sub. Code: 2905
M.PHARM. DEGREE EXAMINATION
FIRST YEAR
BRANCH II PHARMACEUTICAL CHEMISTRY
PAPER II ADVANCED ORGANIC CHEMISTRY
Q.P. Code: 262905
Time Three hours Maximum 100 Marks
I. Elaborate on: x 20 40)
1. Explain the mechanism and stereo-chemistry of aliphatic nucleophilic substitution
and aromatic electrophilic substitution reaction.
2. Classify heterocyclic compounds with examples. Write the preparation and
properties of a fused ring structure containing hetero atom.
Write in brief about nitrenes.
II. Write notes on: (10 x 6 60)
1. How are chiral drugs prepared? Mention the importance of chiral drugs.
2. Synthones for carbon-carbon bond formation.
3. Types of Pericyclic reactions with examples.
4. Concepts of Nanochemistry.
5. Write the mechanism of Michael reaction. Mention its applications.
6. What is parallel synthesis? Give an example.
7. Write a note on addition reactions with examples.
8. How is an aldehyde group protected during organic synthesis?
9. Explain the generation, fate and biological significance of free radicals.
10. Discuss in detail the mechanisms involved in elimination reactions.
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- biological standardisation and pharmacological screening methods (262912)
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- clinical pharmacy (262922)
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- industrial pharmacy (262902)
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- pharmacology and toxicology (262911)
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- phytochemistry and biotechnology(262910)(no candidate)