THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
[LO 814] MAY 2019 Sub. Code: 3814
PHARM. D DEGREE EXAMINATION
(2009-2010 Regulation)
THIRD YEAR
PAPER II PHARMACEUTICAL ANALYSIS
Q.P. Code: 383814
Time Three hours Maximum 70 Marks
I. Elaborate on: x 10 40)
1. With a neat schematic diagram, explain the types of Pumps, Solvent Degassing
system and detectors of HPLC.
2. What is electrophoresis? Explain the various methods of paper electrophoresis.
3. Explain the principle of liquid-liquid partition chromatography and write about the
detection techniques in TLC.
4. State Beer's and Lambert's law. Explain the effect of solvent on absorption
spectra. Define Auxochrome and hypsochromic shift.
II. Write notes on: x 5 30)
1. What are the differences between atomic absorption and flame emission
spectroscopy?
2. Write the theory of NMR Spectroscopy.
3. What is group frequency and finger print region in IR Spectroscopy?
4. What is quenching? Write about the different types of quenching?
5. Distinguish between polarography and amperometry.
6. Explain the principle and instrumentation of polarimeter.