Seat No.: Enrolment No.
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER-V EXAMINATION WINTER-2016
Subject Code: 2250005 Date: 02/12/2016
Subject Name: Pharmacology and Pharmacotherapeutics I
Time: 10.30 am 01.30 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Classify antihistaminics. Discuss its pharmacological actions adverse effects.
06

Discuss pharmacological and pathophysiological actions of 5-HT.
05

Outline biosynthesis of prostaglandins. Explain its pharmacological actions and therapeutic uses.
05
Q.2

Discuss complete pharmacology of β-adrenergic blocking agents.
06

Classify sympathomimetic drugs according to their therapeutic uses. Add a note on amphetamine.
05

Differentiate between following
1. Autonomic and somatic nervous system.
2. Sympathetic and Parasympathetic nervous system.
05
Q.3

Classify peripherally acting skeletal muscle relaxants. Explain their mechanism of action.
06

Classify local anesthetics. Write about adverse effects, uses techniques of local anesthesia.
05

Give an account on pharmacology of ondansetron.
05
Q.4

Write about synthesis, storage, uptake metabolism of catecholamines.
06

Discuss complete pharmacology of antidiarrhoeal drugs with special emphasis on ORT.
05

Write a note cholinergic receptors.
05
Q.5

Discuss pharmacological actions of acetylcholine on heart, blood vessels, eye skeletal muscle.
06

Write about anticholinesterases.
05

Explain therapeutic uses of atropine.
05
Q. 6

Explain pathogenesis of bronchial asthma.
06

Write symptoms, diagnosis treatment of peptic ulcer disease.
05

Write a note on ganglionic stimulants.
05
Q.7

Discuss epidemiology, pathophysiology and diagnosis of hepatitis.
06

Write about management and treatment of open-angle glaucoma.
05

Define antitussives. Enlist drugs used for this purpose describe any one drug.
05