Seat No.: Enrolment
GUJARAT TECHNOLOGICAL UNIVERSITY
B. Pharm. SEMESTER III • EXAMINATION WINTER • 2016
Subject Code: 230004 Date: 25-11-2016
Subject Name: Pharmaceutical Analysis I
Time: 02:30 pm 05:00 pm Total Marks: 80
Instructions:
1. Attempt any five questions.
2. Make suitable assumptions wherever necessary.
3. Figures to the right indicate full marks.
Q.1

Explain terms
1. Molarity 2. Primary standard substance 3.Back titration 4.Self indicator
5. Post precipitation 6.LOQ
06

Write a note on Diazotization titration.
05

Write a note on common ion effect.
05
Q.2

What is error? Classify the error and how will you minimize the error?
06

Differentiate between QA and QC.
05

What is analytical method validation? Enlist validation parameter. Discuss any two parameters in detail.
05
Q.3

What is hydrolysis?
Derive equation for finding pH of aqueous solution of salt of weak acid and strong base.
06

Discuss Resonance theory of indicator.
05

What is importance of non-aqueous titration?
Discuss Differentiating and Leveling effect of solvent.
05
Q.4

Give the types of Redox titration. Discuss Permanganometry in detail.
06

Discuss various types of indicators used in redox titration.
05

Differentiate Iodometric and Iodimetric titrations.
05
Q.5

Enlist the different types of complexometric titration.
Explain Fajan's method in detail.
06

What is Argentometric titration? Write a note on Volhard's method.
05

Explain masking and demasking in complexometric titration.
05
Q. 6

What is Co-precipitation?
Give types of Co-precipitation and note on common source of co-precipitation.
06

What is gravimetric analysis? Enlist the steps involved in gravimetric analysis.
05

Ksp of PbI2 is 7.2 X 10-9. Calculate molar solubility and solubility in g/ml. Molecular weight of PbI2 is 461 g/mol.
05
Q.7

Write a note on Karl-Fischer titration
06

Explain: Why multiple extraction is better than single extraction?
05

Give detail note on continuous extractions.
05